2023
Impact of Risk Factors on COVID‐19 Outcomes in Unvaccinated People With Rheumatic Diseases: A Comparative Analysis of Pandemic Epochs Using the COVID‐19 Global Rheumatology Alliance Registry
Yazdany J, Ware A, Wallace Z, Bhana S, Grainger R, Hachulla E, Richez C, Cacoub P, Hausmann J, Liew J, Sirotich E, Jacobsohn L, Strangfeld A, Mateus E, Hyrich K, Gossec L, Carmona L, Lawson‐Tovey S, Kearsley‐Fleet L, Schaefer M, Ribeiro S, Al‐Emadi S, Hasseli R, Müller‐Ladner U, Specker C, Schulze‐Koops H, Bernardes M, Fraga V, Rodrigues A, Sparks J, Ljung L, Di Giuseppe D, Tidblad L, Wise L, Duarte‐García A, Ugarte‐Gil M, Colunga‐Pedraza I, Martínez‐Martínez M, Alpizar‐Rodriguez D, Xavier R, Isnardi C, Pera M, Pons‐Estel G, Izadi Z, Gianfrancesco M, Carrara G, Scirè C, Zanetti A, Machado P. Impact of Risk Factors on COVID‐19 Outcomes in Unvaccinated People With Rheumatic Diseases: A Comparative Analysis of Pandemic Epochs Using the COVID‐19 Global Rheumatology Alliance Registry. Arthritis Care & Research 2023, 76: 274-287. PMID: 37643903, DOI: 10.1002/acr.25220.Peer-Reviewed Original ResearchB-cell depleting therapySevere COVID-19Rheumatic diseasesCOVID-19 outcomesUnvaccinated peopleRisk factorsWorse outcomesCOVID-19Severe COVID-19 outcomesTumor necrosis factor inhibitorsHigh disease activityNecrosis factor inhibitorsConnective tissue diseaseCOVID-19 severityCOVID-19 vaccineThird of individualsLogistic regression modelsCOVID-19 diagnosisOrdinal logistic regression modelsLow HDI regionsMore comorbiditiesUnvaccinated patientsDisease activityUnvaccinated individualsFactor inhibitors
2022
Obstetric outcomes in women with rheumatic disease and COVID-19 in the context of vaccination status
Maguire S, Al-Emadi S, Alba P, Aguiar M, Al Lawati T, Alle G, Bermas B, Bhana S, Branimir A, Bulina I, Clowse M, Cogo K, Colunga I, Cook C, Cortez K, Dao K, Gianfrancesco M, Gore-Massey M, Gossec L, Grainger R, Hausman J, Hsu T, Hyrich K, Isnardi C, Kawano Y, Kilding R, Kusevich D, Lawson-Tovey S, Liew J, McCarthy E, Montgumery A, Moyano S, Nasir N, Padjen I, Papagoras C, Patel N, Pera M, Pisoni C, Pons-Estel G, Quiambao A, Quintana R, Ruderman E, Sattui S, Savio V, Sciascia S, Sencarova M, Morales R, Siddique F, Sirotich E, Sparks J, Strangfeld A, Sufka P, Tanner H, Tissera Y, Wallace Z, Werner M, Wise L, Worthing A, Zell J, Zepa J, Machado P, Yazdany J, Robinson P, Conway R. Obstetric outcomes in women with rheumatic disease and COVID-19 in the context of vaccination status. Rheumatology 2022, 62: 1621-1626. PMID: 36124987, PMCID: PMC11181869, DOI: 10.1093/rheumatology/keac534.Peer-Reviewed Original ResearchConceptsObstetric outcomesPreterm birthVaccination statusPregnant womenUnvaccinated womenCOVID-19Exact testCOVID-19 vaccination statusCOVID-19 vaccine dosesCOVID-19 vaccinationCOVID-19 infectionFisher's exact testCOVID-19 diagnosisVaccine doseHospital admissionRheumatic diseasesMore dosesVaccine dosesPharmacological treatmentMusculoskeletal diseasesPregnancyDescriptive studyWomenOutcomesGreater numberFactors associated with severe COVID-19 in people with idiopathic inflammatory myopathy: results from the COVID-19 Global Rheumatology Alliance physician-reported registry
Yeoh S, Gianfrancesco M, Lawson-Tovey S, Hyrich K, Strangfeld A, Gossec L, Carmona L, Mateus E, Schäfer M, Richez C, Hachulla E, Holmqvist M, Scirè C, Lorenz H, Voll R, Hasseli R, Jayatilleke A, Hsu T, D’Silva K, Pimentel-Quiroz V, del Mercado M, Shinjo S, dos Reis Neto E, da Rocha L, de Oliveira e Silva Montandon A, Pons-Estel G, Ornella S, Exeni M, Velozo E, Jordan P, Sirotich E, Hausmann J, Liew J, Jacobsohn L, Gore-Massy M, Sufka P, Grainger R, Bhana S, Wallace Z, Robinson P, Yazdany J, Machado P. Factors associated with severe COVID-19 in people with idiopathic inflammatory myopathy: results from the COVID-19 Global Rheumatology Alliance physician-reported registry. RMD Open 2022, 8: e002508. PMID: 36100295, PMCID: PMC9471207, DOI: 10.1136/rmdopen-2022-002508.Peer-Reviewed Original ResearchConceptsIdiopathic inflammatory myopathiesSevere COVID-19Prednisolone-equivalent doseHigh disease activityDisease activityInflammatory myopathiesMale sexSevere outcomesCOVID-19Multivariable ordinal logistic regressionOlder ageHigher comorbidity burdenLarge registry dataCOVID-19 diagnosisComorbidity burdenRituximab exposureClinical characteristicsRisk stratificationOrdinal logistic regressionRegistry dataHospitalisationSeverity ScaleDemographic dataLogistic regressionPatientsDevelopment of a Prediction Model for COVID‐19 Acute Respiratory Distress Syndrome in Patients With Rheumatic Diseases: Results From the Global Rheumatology Alliance Registry
Izadi Z, Gianfrancesco M, Aguirre A, Strangfeld A, Mateus E, Hyrich K, Gossec L, Carmona L, Lawson‐Tovey S, Kearsley‐Fleet L, Schaefer M, Seet A, Schmajuk G, Jacobsohn L, Katz P, Rush S, Al‐Emadi S, Sparks J, Hsu T, Patel N, Wise L, Gilbert E, Duarte‐García A, Valenzuela‐Almada M, Ugarte‐Gil M, Ribeiro S, de Oliveira Marinho A, de Azevedo Valadares L, Di Giuseppe D, Hasseli R, Richter J, Pfeil A, Schmeiser T, Isnardi C, Torres A, Alle G, Saurit V, Zanetti A, Carrara G, Labreuche J, Barnetche T, Herasse M, Plassart S, Santos M, Rodrigues A, Robinson P, Machado P, Sirotich E, Liew J, Hausmann J, Sufka P, Grainger R, Bhana S, Costello W, Wallace Z, Yazdany J, Registry G. Development of a Prediction Model for COVID‐19 Acute Respiratory Distress Syndrome in Patients With Rheumatic Diseases: Results From the Global Rheumatology Alliance Registry. ACR Open Rheumatology 2022, 4: 872-882. PMID: 35869686, PMCID: PMC9350083, DOI: 10.1002/acr2.11481.Peer-Reviewed Original ResearchAcute respiratory distress syndromeRisk score calculatorCOVID-19 acute respiratory distress syndromeRespiratory distress syndromeScore calculatorCOVID-19 diagnosisDistress syndromeRheumatic diseasesCoronavirus disease 2019 acute respiratory distress syndromeIndependent registriesCOVID-19 disease progressionRegression modelsKey risk factorsRisk stratificationARDS outcomeRisk factorsDisease progressionHighest mean AUCHigh riskPatientsMean AUCClinical settingRegistryMonoclonal antibodiesSyndrome
2021
COVID-19 in women with rheumatic disease who are pregnant: Data from the COVID-19 Global Rheumatology Alliance
Bermas B, Gianfrancesco M, Tanner H, Seet A, Aguiar M, Al Adhoubi N, Al Emadi S, Cunha B, Flood R, Kusevich D, McCarthy E, Patel N, Ruderman E, Sattui S, Sciascia S, Siddique F, Valenzuela-Almada M, Wise L, Worthing A, Zell J, Bhana S, Costello W, Duarte-Garcia A, Grainger R, Gossec L, Hausmann J, Hyrich K, Lawson-Tovey S, Liew J, Sirotich E, Sparks J, Sufka P, Wallace Z, Machado P, Strangfeld A, Clowse M, Yazdany J, Robinson P. COVID-19 in women with rheumatic disease who are pregnant: Data from the COVID-19 Global Rheumatology Alliance. The Journal Of Rheumatology 2021, 49: 110-114. PMID: 34470798, DOI: 10.3899/jrheum.210480.Peer-Reviewed Original ResearchConceptsRheumatic diseasesPregnant womenPregnancy outcomesObstetric detailsCOVID-19Combination of antimalarialsRheumatic disease diagnosisLopinavir/ritonavirSystemic lupus erythematosusCases of patientsCOVID-19 infectionCoronavirus disease 2019Time of infectionCOVID-19 diagnosisTime of reportAntiphospholipid syndromeInflammatory arthritidesPreterm birthLupus erythematosusMedian ageTerm birthsRheumatoid arthritisSupplemental oxygenArthritis/Medication treatmentImmediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases
Hausmann J, Kennedy K, Simard J, Liew J, Sparks J, Moni T, Harrison C, Larché M, Levine M, Sattui S, Semalulu T, Foster G, Surangiwala S, Thabane L, Beesley R, Durrant K, Mateus E, Mingolla S, Nudel M, Palmerlee C, Richards D, Liew D, Hill C, Bhana S, Costello W, Grainger R, Machado P, Robinson P, Sufka P, Wallace Z, Yazdany J, Sirotich E, Alliance C, Robinson P, Bhana S, Liew J, Sufka P, Singh N, Howard R, Kim A, Westrich-Robertson T, Sirotich E, Tsui E, Duarte-Garcia A, Sparks J, Tam H, Jayatilleke A, Konig M, Graef E, Putman M, Syed R, Korsten P, Mateus E, Sattui S, Wallace Z, Laura U, Adam K, Chock Y, White D, Zamora G, Traboco L, Patel A, Grainger R, Ugarte-Gil M, Gianfrancesco M, Amigues I, Sanchez-Alvarez C, Trupin L, Jacobsohn L, Beesley R, Hoyer B, Machado P, Makan K, Gossec L, Priyank C, Leipe J, Wallace B, Angeles-Han S, Almaghlouth I, Katherine W, Padula A, Berenbaum F, Treemarcki E, Sinha R, Lewandowski L, Webb K, Young K, Bulina I, Uribe S, Rubinstein T, Nolan M, Ang E, Venuturupalli S, Hausmann J, Dubreuil M, Pisoni C, Cosatti M, Campos J, Simard J, Conway R, Peterson T, Harrison C, Felix C, Richards D, Proulx L, Akpabio A, Worthing A, Laidlaw L, Reid P, Palmerlee C, Danila M, Sahar L, Linh N, Agarwal A, Studenic P, Liew D, Larche M, Mingolla S, Zamora E, Angevare S, Sinha R, Durrant K, Peirce A, Somers E, Cappelli L, Frankel B, Kumar B, Krupnikova S, Vega J, Frankovich J, Fernandez-Ruiz R, Velásquez M, Yeoh S, Marino M, Nudel M, Scott C, Rodríguez C, Mancheño A, Seo P, Gamboa-Cárdenas R, Pimentel-Quiroz V, Reátegui-Sokolova C, Kihara M, Lin C, Kattula D, Laila G, Carmona L, Wallace J, Yazdany J, Costello W, Gore-massy M, Tomasella L, Kodek M. Immediate effect of the COVID-19 pandemic on patient health, health-care use, and behaviours: results from an international survey of people with rheumatic diseases. The Lancet Rheumatology 2021, 3: e707-e714. PMID: 34316727, PMCID: PMC8298011, DOI: 10.1016/s2665-9913(21)00175-2.Peer-Reviewed Original ResearchRheumatic disease diagnosisRheumatic diseasesHealth care accessCOVID-19 diagnosisNon-inflammatory rheumatic diseasesSARS-CoV-2 exposureAdults age 18 yearsCOVID-19 pandemicRheumatic disease activityAutoimmune rheumatic diseasesSystemic lupus erythematosusHealth care useAge 18 yearsCOVID-19 exposurePatient experience surveysProtective behaviorsPublic health advicePatient support organisationsAntirheumatic medicationsMedication affordabilityDisease activityComplete responseLupus erythematosusRheumatoid arthritisSjögren's syndromeOP0288 MACHINE LEARNING ALGORITHMS TO PREDICT COVID-19 ACUTE RESPIRATORY DISTRESS SYNDROME IN PATIENTS WITH RHEUMATIC DISEASES: RESULTS FROM THE GLOBAL RHEUMATOLOGY ALLIANCE PROVIDER REGISTRY
Izadi Z, Gianfrancesco M, Hyrich K, Strangfeld A, Gossec L, Carmona L, Mateus E, Lawson-Tovey S, Trupin L, Rush S, Schmajuk G, Jacobsohn L, Katz P, Al Emadi S, Wise L, Gilbert E, Valenzuela-Almada M, Duarte-Garcia A, Sparks J, Hsu T, D’silva K, Serling-Boyd N, Bhana S, Costello W, Grainger R, Hausmann J, Liew J, Sirotich E, Sufka P, Wallace Z, Machado P, Robinson P, Yazdany J. OP0288 MACHINE LEARNING ALGORITHMS TO PREDICT COVID-19 ACUTE RESPIRATORY DISTRESS SYNDROME IN PATIENTS WITH RHEUMATIC DISEASES: RESULTS FROM THE GLOBAL RHEUMATOLOGY ALLIANCE PROVIDER REGISTRY. Annals Of The Rheumatic Diseases 2021, 80: 175.2-176. DOI: 10.1136/annrheumdis-2021-eular.446.Peer-Reviewed Original ResearchAcute respiratory distress syndromeDevelopment of acute respiratory distress syndromeTime of COVID-19 diagnosisNegative predictive valuePositive predictive valueGlobal Rheumatology AllianceRheumatic diseasesBristol-Myers SquibbGrant/research supportPredictive valueArea under curveCOVID-19 Global Rheumatology AllianceRisk factors associated with acute respiratory distress syndromeGlobal cohort of patientsPre-existing rheumatic diseaseRisk of acute respiratory distress syndromeAnti-CD20 monoclonal antibodyAcute respiratory distress syndrome diagnosisTumor necrosis factor inhibitorsBristol-MyersCOVID-19 diagnosisRespiratory distress syndromeCohort of patientsInterstitial lung diseaseLife-threatening complicationsOP0286 CHARACTERISTICS ASSOCIATED WITH SEVERE COVID-19 OUTCOMES IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): RESULTS FROM THE COVID-19 GLOBAL RHEUMATOLOGY ALLIANCE (COVID-19 GRA)
Ugarte-Gil M, Alarcon G, Seet A, Izadi Z, Reategui Sokolova C, Clarke A, Wise L, Pons-Estel G, Santos M, Bernatsky S, Mathias L, Lim N, Sparks J, Wallace Z, Hyrich K, Strangfeld A, Gossec L, Carmona L, Mateus E, Lawson-Tovey S, Trupin L, Rush S, Schmajuk G, Katz P, Jacobsohn L, Al Emadi S, Gilbert E, Duarte-Garcia A, Valenzuela-Almada M, Hsu T, D’silva K, Serling-Boyd N, Dieudé P, Nikiphorou E, Kronzer V, Singh N, Wallace B, Akpabio A, Thomas R, Bhana S, Costello W, Grainger R, Hausmann J, Liew J, Sirotich E, Sufka P, Robinson P, Machado P, Gianfrancesco M, Yazdany J. OP0286 CHARACTERISTICS ASSOCIATED WITH SEVERE COVID-19 OUTCOMES IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): RESULTS FROM THE COVID-19 GLOBAL RHEUMATOLOGY ALLIANCE (COVID-19 GRA). Annals Of The Rheumatic Diseases 2021, 80: 173.2-175. DOI: 10.1136/annrheumdis-2021-eular.2984.Peer-Reviewed Original ResearchSystemic lupus erythematosusChronic renal diseaseModerate/high disease activityNon-invasive ventilationSevere COVID-19 outcomesBristol-Myers SquibbDisease activityGrant/research supportRenal diseaseCOVID-19 outcomesCOVID-19 diagnosisDrug monotherapyImmunomodulatory therapyGlobal Rheumatology AllianceMembrane oxygenationCOVID-19 Global Rheumatology AllianceNational Institute for Health ResearchMale sexModerate to high daily dosesSLE adult patientsBristol-MyersSystemic lupus erythematosus patientsSystemic lupus erythematosus therapyCardiovascular diseaseOdds of poor outcome
2020
Characteristics associated with Covid-19 in patients with Rheumatic Disease in Latin America: data from the Covid-19 Global Rheumatology Alliance physician-reported registry
Ugarte-Gil M, Marques C, Alpizar-Rodriguez D, Pons-Estel G, Xibille-Friedmann D, Paiva E, Zamora-Tehozol E, Gamboa-Cárdenas R, Quintana R, Rodriguez-Reyna T, Sepúlveda A, Gianfrancesco M, Evans M, Wallace Z, Sirotich E, Omedo E, Hausmann J, Alarcón G, Robinson P, Yazdany J. Characteristics associated with Covid-19 in patients with Rheumatic Disease in Latin America: data from the Covid-19 Global Rheumatology Alliance physician-reported registry. Global Rheumatology 2020 DOI: 10.46856/grp.10.e003.Peer-Reviewed Original ResearchOdds ratioRheumatic diseasesConfidence intervalsCharacteristics of patientsSystemic lupus erythematosusMultivariable logistic regressionFrequent rheumatic diseasesCOVID-19 diagnosisVentilatory supportLupus erythematosusRheumatoid arthritisDisease featuresPatientsLogistic regressionCOVID-19T-testMortalityDiseaseGroupErythematosusComorbiditiesHospitalizationArthritisRegistryPhysicians