Elizabeth Horn Prsic, MD
Cards
Appointments
Additional Titles
Firm Chief, Medical Oncology
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Additional Titles
Firm Chief, Medical Oncology
Are You a Patient?
View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
View Doctor ProfileAppointments
Additional Titles
Firm Chief, Medical Oncology
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Titles
Associate Professor of Internal Medicine (Medical Oncology & Hematology)
Firm Chief, Medical Oncology
Biography
Dr. Elizabeth Prsic is a physician specializing in medical oncology and palliative care. She received her medical degree from the George Washington School of Medicine. She completed internal medicine residency and medical oncology fellowship at Brown University. Dr. Prsic received a T32 NIH Ruth L. Kirschstein National Research Service award and completed a research fellowship through the Division of Hematology Oncology at Brown University where she focused on end-of-life and palliative care. During research fellowship, she studied cancer epidemiology, biostatistics and health policy at the Brown University School of Public Health.
Dr. Prsic is an associate professor at Yale Medical School and serves as an attending physician at the Smilow Cancer Hospital and Yale New Haven Hospital. Her research interests include supportive oncology, symptom management, end-of-life care and health care quality. She is passionate about supporting patients with advanced cancer and their caregivers. Dr. Prsic is dedicated to serving patients with serious or life-limiting illness with complex medical needs or difficult-to-control symptoms. She is committed to medical education and academic mentorship.
Appointments
Medical Oncology and Hematology
Associate Professor on TermPrimary
Other Departments & Organizations
Education & Training
- Fellowship in Palliative Medicine
- University of Washington
- Fellowship in Medical Oncology
- Brown University
- Residency
- Brown University
- Internship
- Brown University
- MD
- George Washington University School of Medicine
- BA
- Tulane University
Research
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Overview
Medical Research Interests
Public Health Interests
ORCID
0000-0003-1364-5599
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Jensa Morris, MD
Maureen Canavan, PhD, MPH
Jennifer Kapo, MD
Kerin Adelson, MD
Alex Choi, MD
Bonnie E Gould Rothberg, MD, PhD, MPH, MMM, FACP
Medical Oncology
Publications
2025
The use of tramadol for cancer-associated pain—a systematic review
Garlapati S, Alexander R, Kaminski C, Challa P, Nemeth Z, Bruera E, Chow R, Prsic E. The use of tramadol for cancer-associated pain—a systematic review. Supportive Care In Cancer 2025, 33: 1152. PMID: 41324745, PMCID: PMC12669292, DOI: 10.1007/s00520-025-10098-4.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsSafety of tramadolCancer-associated painRandomized controlled trial designSystematic reviewObservational study designQuality of lifeComprehensive systematic reviewRandomized Controlled TrialsSafety endpointsNarrative synthesisPatient-centered treatment strategiesCohort studyPropensity-score matching analysisStudy designCancer painCochrane CENTRALControlled TrialsTrials of efficacyMethodsOvid MEDLINEResultsEleven studiesTrial designEfficacy endpointSafety profilePainComparative trialsMedical education on inpatient medical oncology service before and after oncology hospitalist program
Chow R, Kaminski C, Zhou E, Mendoza H, Rusheen J, Parker N, Schor S, Gupta J, Jaiani A, Morris J, Prsic E. Medical education on inpatient medical oncology service before and after oncology hospitalist program. BMC Medical Education 2025, 25: 1450. PMID: 41121186, PMCID: PMC12539143, DOI: 10.1186/s12909-025-07142-6.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsSurveyed post-implementationInternal medicine residentsHospitalist programPost-implementationMedicine residentsExperiences of internal medicine residentsSmilow Cancer HospitalMedical oncology serviceFree-text fieldsHospitalist modelOncology rotationEducational experiencePre-implementationConsultant physiciansOncology servicesMedical educationHospital outcomesResident educationGeneral satisfactionLikert scaleTeaching serviceCancer HospitalHospitalistsOncologyOncology facultyEstablishing a Health System Policy for Proportionate Palliative Sedation
Rutherford A, Bui T, Gupta J, Choi A, Tenenbaum L, Tolchin B, Morrison L, Jubanyik K, Gelb R, Pinney A, Sussman L, Sangal R, Prsic E. Establishing a Health System Policy for Proportionate Palliative Sedation. Journal Of Pain & Palliative Care Pharmacotherapy 2025, ahead-of-print: 1-9. PMID: 41042797, DOI: 10.1080/15360288.2025.2564538.Peer-Reviewed Original ResearchConceptsProportionate palliative sedationPalliative sedationPatient-centered careHealth system policiesEnd of lifeLocal practice patternsMoral distressIntractable sufferingClinical guidelinesYale-New Haven HospitalMoral supportPractice patternsPolicy development processProfessional organizationsNew Haven HospitalInstitutional guidelinesEthical challengesSystem policiesGuidelinesPatient comfortEthical analysisCliniciansCaregiversCareRobust discussionTemporal Trends in Opioid Use and Associated Outcomes for Patients Living with Advanced Cancer
Jairam V, Lindsay M, Soulos P, Gross C, Prsic E, Baum L, Park H. Temporal Trends in Opioid Use and Associated Outcomes for Patients Living with Advanced Cancer. Journal Of Pain And Symptom Management 2025, 70: 230-238.e7. PMID: 40403779, DOI: 10.1016/j.jpainsymman.2025.05.007.Peer-Reviewed Original ResearchAltmetricConceptsPain-related ED visitsOpioid useGabapentinoid useOpioid-related encountersAdvanced cancerOpioid prescribingED visitsAdvanced solid tumor cancersEnd Results (SEER)-Medicare databaseHigh-risk opioid useNonopioid pain medicationsMultivariate logistic regression modelNon-cancer patientsSolid tumor cancersPain controlPain medicationInvestigate time trendsIndex dateLogistic regression modelsCancer cohortOpioidNoncancer patientsOpioid epidemicPatientsNoncancer cohortStereotactic Anterior Cingulotomy in a Patient With a Sacral Giant Cell Tumor
Ostas A, Prsic E. Stereotactic Anterior Cingulotomy in a Patient With a Sacral Giant Cell Tumor. Journal Of Pain And Symptom Management 2025, 69: e656. DOI: 10.1016/j.jpainsymman.2025.02.346.Peer-Reviewed Original ResearchCitationsConceptsAmerican Society of Pain and NeuroscienceRefractory cancer painAnterior cingulotomyCancer painCancer-related painGiant cell tumorAnterior cingulate cortexIntractable painCell tumorsPain reliefInterventional therapyManagement of cancer-associated painNeurosurgical interventionMedically refractory cancer painSacral giant cell tumorTreatment of chronic intractable painTreatment of cancer-related painEmotional processing of painEpidural steroid injectionsIntractable cancer painTumor-related complicationsChronic intractable painAdequate pain reliefCancer-associated painProcessing of painEfficacy of cannabinoids for the prophylaxis of chemotherapy-induced nausea and vomiting—a systematic review and meta-analysis
Chow R, Basu A, Kaur J, Hui D, Im J, Prsic E, Boldt G, Lock M, Eng L, Ng T, Zimmermann C, Scotte F. Efficacy of cannabinoids for the prophylaxis of chemotherapy-induced nausea and vomiting—a systematic review and meta-analysis. Supportive Care In Cancer 2025, 33: 193. PMID: 39953210, PMCID: PMC11828838, DOI: 10.1007/s00520-025-09251-w.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChemotherapy-induced nausea and vomitingEfficacy of cannabinoidsTHC:CBDMeta-analysisPrevention of chemotherapy-induced nausea and vomitingProphylaxis of chemotherapy-induced nausea and vomitingChemotherapy-induced nausea and vomiting controlControlled TrialsCochrane Central Register of Controlled TrialsCentral Register of Controlled TrialsRegister of Controlled TrialsNausea and vomitingChemotherapy-induced nauseaMethodsA literature searchCochrane Central RegisterComplete responseRandomized Controlled TrialsNo vomitingAdjunctive therapyRescue medicationAntiemetic regimensComposite endpointSubgroup analysisCannabinoidSecondary preventionInpatient Immunotherapy Outcomes Study: A Multicenter Retrospective Analysis
Riaz F, Vaughn J, Zhu H, Dickerson J, Sayegh H, Brongiel S, Baldwin E, Kier M, Zaemes J, Hearn C, Abdelghany O, Cohen R, Parikh R, Reuss J, Prsic E, Doroshow D. Inpatient Immunotherapy Outcomes Study: A Multicenter Retrospective Analysis. JCO Oncology Practice 2025, 21: 1165-1173. PMID: 39937997, DOI: 10.1200/op-24-00788.Peer-Reviewed Original ResearchCitationsAltmetricConceptsImmune checkpoint inhibitorsOverall survivalICI administrationSolid malignanciesPatients treated with immune checkpoint inhibitorsAdministration of immune checkpoint inhibitorsMultivariate Cox proportional hazards model analysisResponse to ICI therapyCox proportional hazards model analysisProportional hazards model analysisAdvanced solid malignanciesKaplan-Meier methodOutcomes of patientsInstitutional electronic medical recordsHazards model analysisCox proportional hazards modelsProportional hazards modelCheckpoint inhibitorsICI therapyMedian OSICI initiationICI useRetrospective studyClinical outcomesClinicodemographic variablesEnteral and parenteral nutrition in patients with cancer: complication rates compared—updated systematic review and meta-analysis
Chow R, Im J, Arends J, Del Fabbro E, Mortensen-Truscott L, Qeska D, Balaji S, Walsh C, Watson G, Lock M, Prsic E, Eng L, Zimmermann C, Bruera E. Enteral and parenteral nutrition in patients with cancer: complication rates compared—updated systematic review and meta-analysis. BMJ Supportive & Palliative Care 2025, 15: 281-290. PMID: 39890439, DOI: 10.1136/spcare-2024-005244.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCumulative meta-analysisNutrition support complicationsSystematic reviewProtein-energy malnutritionEnteral nutritionParenteral nutritionMeta-analysisRandomised controlled trialsSubgroup analysisLeave-one-out analysisStandard careEffect estimatesControlled TrialsType I errorComplication rateComplicationsAdultsNutritionPatientsInfectionInfection rateCancerMortalityEndpointChildren
2024
Multidisciplinary Lessons from Palliative Extubations at Home
Breyre A, Grammatico M, Policastro A, Ingram C, Prsic E, Sussman L, Couturier K. Multidisciplinary Lessons from Palliative Extubations at Home. Prehospital Emergency Care 2024, 29: 698-701. PMID: 39475704, DOI: 10.1080/10903127.2024.2420198.Peer-Reviewed Original ResearchAltmetricMulti-day vs single-day dexamethasone for the prophylaxis of chemotherapy-induced nausea and vomiting: systematic review and meta-analysis
Chow R, Celio L, Im J, Caini S, Eng L, Prsic E, Scotté F, Aapro M. Multi-day vs single-day dexamethasone for the prophylaxis of chemotherapy-induced nausea and vomiting: systematic review and meta-analysis. Supportive Care In Cancer 2024, 32: 736. PMID: 39432169, DOI: 10.1007/s00520-024-08934-0.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsDexamethasone-sparing regimenChemotherapy-induced nausea and vomitingModerately emetogenic chemotherapyHighly emetogenic chemotherapyRandomized Controlled TrialsComplete responseMeta-analysisEmetogenic chemotherapyNo vomitingRescue medicationProphylaxis of chemotherapy-induced nausea and vomitingSystematic reviewSchedule of dexamethasoneNausea and vomitingChemotherapy-induced nauseaResultsTen trialsAntiemetic regimenCumulative meta-analysisEffect estimatesSafety profileComprehensive systematic reviewMethodsOvid MEDLINERegimensAdult cancer patientsCancer patients
Academic Achievements & Community Involvement
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Activities
activity New England Journal of Medicine - Journal Watch
2023 - PresentJournal ServiceGuest EditorDetailsGuest Editor for Palliative Care and Supportive Oncologyactivity National Comprehensive Cancer Network
2022 - PresentProfessional OrganizationsCommittee MemberDetailsSupportive Care Guidelines, Adult Cancer Painactivity Cancer Medicine
2022 - 2023Journal ServiceAssociate Editoractivity Smilow Cancer Hospital Oncology Patient and Safety Quality Committee
2018 - 2019CommitteesParticipantactivity Yale Palliative Care Program, Fellowship Committee
2018 - 2019CommitteesMember
Honors
honor Patient Experience Award for Caring and Excellence
12/01/2023Hospital System AwardYale New Haven Hospitalhonor Smilow Luminary Award
10/01/2020Hospital System AwardSmilow Cancer HospitalDetailsUnited States
Clinical Care
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Overview
Elizabeth Prsic, MD, is a medical oncologist and palliative medicine physician who specializes in the inpatient care of patients with advanced cancer. She works with an interdisciplinary team to help support patients who are facing serious illness and their caregivers.
Dr. Prsic’s research interests include inpatient supportive oncology care, symptom management, and end-of-life care among patients with advanced cancer. She earned her medical degree from the George Washington University School of Medicine. She completed her internal medicine internship, residency, and medical oncology fellowship at Brown University’s Warren Alpert Medical School, where she also completed a National Institutes of Health-funded research fellowship focusing on end-of-life care. She completed her hospice and palliative medicine fellowship at the University of Washington.
She is an associate professor at Yale School of Medicine, and serves as the firm chief for medical oncology.
Clinical Specialties
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View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
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News
- December 15, 2025
Yale Department of Internal Medicine Faculty Promotions and Appointments (December 2025)
- December 31, 2024
YCC Publications 2024
- April 26, 2024
Gastrointestinal Cancer CME Series
- April 24, 2024Source: MedScape
How These Young MDs Impressed the Hell Out of Their Bosses
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