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INFORMATION FOR

    Ted Melnick, MD, MHS

    Associate Professor of Emergency Medicine and of Biostatistics (Health Informatics)
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    Additional Titles

    Section Chief for Research, Emergency Medicine

    Director, Clinical Informatics Fellowship

    Associate Professor of Biomedical Informatics & Data Science, Biomedical Informatics & Data Science

    ACCELERATE Lab

    Yale lab designing, implementing, and evaluating human-centered digital health, AI, CDS, and learning health systems to improve care at scale.

    About

    Titles

    Associate Professor of Emergency Medicine and of Biostatistics (Health Informatics)

    Section Chief for Research, Emergency Medicine; Director, Clinical Informatics Fellowship; Associate Professor of Biomedical Informatics & Data Science, Biomedical Informatics & Data Science

    Biography

    Dr. Melnick is a nationally recognized clinician-scientist in emergency medicine, clinical informatics, and health services research whose work focuses on using digital health systems to improve care and generate evidence within routine clinical practice. His research integrates human-centered design, electronic health record (EHR) data, clinical decision support, implementation science, measurement science, and pragmatic clinical trials. Across this work, he has helped advance the EHR from a record of care and platform for deploying tools into infrastructure for clinical investigation: making clinical work measurable, evidence-based interventions actionable, and their effects rigorously evaluable at scale.

    He has served as Principal Investigator of multiple federally funded studies, including the NIH-funded EMBED pragmatic trial across five health systems and the ongoing NIDA-supported ADAPT R33. EMBED evaluated human-centered, workflow-integrated decision support for emergency department initiation of buprenorphine and demonstrated that well-designed digital interventions can change clinician behavior while also revealing barriers between adoption and treatment delivery. ADAPT builds directly on those findings through real-time patient identification, direct measurement of intervention exposure and engagement, implementation strategies, and a multiphase optimization approach. In parallel, Dr. Melnick has helped establish EHR audit logs and related metadata as scalable measures of clinical work, linking digital activity with usability, workload, burnout, productivity, patient interaction, workforce attrition, and organizational performance. His recent work extends these methods to emerging AI-enabled technologies and reusable infrastructure for embedded evidence generation and learning health systems.

    Dr. Melnick is Chief of the Research Section in the Department of Emergency Medicine at Yale School of Medicine and Program Director of the Yale/VA Clinical Informatics Fellowship. He is double board-certified in Emergency Medicine and Clinical Informatics and practices clinically at Yale New Haven Hospital. He is deeply committed to mentorship and has trained faculty, fellows, residents, and students across disciplines and career stages, many of whom have pursued careers in clinical informatics, health services research, and academic medicine.

    Last Updated on September 02, 2026.

    Appointments

    Other Departments & Organizations

    Education & Training

    MHS
    Yale University School of Medicine, Clinical Informatics (2014)
    Health Research and Health Policy Training Associate
    Yale School of Medicine (2014)
    Chief Resident
    Mount Sinai School of Medicine (2008)
    Resident
    Mount Sinai School of Medicine (2008)
    Intern
    Mount Sinai School of Medicine (2005)
    MD
    Georgetown University School of Medicine (2004)
    BA
    Williams College (1999)

    Research

    Overview

    Medical Research Interests

    Electronic Health Records; User-Computer Interface

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Ted Melnick's published research.

    Publications

    2026

    Academic Achievements & Community Involvement

    Honors

    • honor

      Young Investigator Award

    • honor

      Plenary Session

    • honor

      AHRQ Mentored Clinical Scientist Research Career Development Award (K08)

    • honor

      Service to Section Award

    • honor

      Informatics Section Grant

    Clinical Care

    Overview

    Ted Melnick, MD, specializes in emergency medicine and clinical informatics, using technology and data to improve healthcare delivery.

    As an associate professor of emergency medicine and biostatistics (health informatics) at Yale School of Medicine, Dr. Melnick is working to improving the use of electronic health records (EHR) and has contributed to research on the relationship between EHR use and physician burnout. He also works on projects to help start treatment for opioid use disorder in emergency settings.

    Dr. Melnick received his medical degree from Georgetown University School of Medicine and completed his residency in emergency medicine at Mount Sinai School of Medicine.

    Clinical Specialties

    Emergency Medicine

    Fact Sheets

    Board Certifications

    • Clinical Informatics

      Certification Organization
      AB of Preventive Medicine
      Original Certification Date
      2016
    • Emergency Medicine

      Certification Organization
      AB of Emergency Medicine
      Original Certification Date
      2009

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