2024
In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization
Kaushik R, McAvay G, Murphy T, Acampora D, Araujo K, Charpentier P, Chattopadhyay S, Geda M, Gill T, Kaminski T, Lee S, Li J, Cohen A, Hajduk A, Ferrante L. In-Hospital Delirium and Disability and Cognitive Impairment After COVID-19 Hospitalization. JAMA Network Open 2024, 7: e2419640. PMID: 38954414, PMCID: PMC11220565, DOI: 10.1001/jamanetworkopen.2024.19640.Peer-Reviewed Original ResearchConceptsIn-hospital deliriumChart-Based Delirium Identification InstrumentOlder adultsFunctional disabilityCOVID-19 hospitalizationCognitive impairmentCohort studyAssociated with increased functional disabilityHospitalized older adultsIncreased functional disabilityAssociation of deliriumPostdischarge follow-upRisk of deliriumTertiary care systemFollow-upPresence of cognitive impairmentProspective cohort studyLogistic regression modelsOlder survivorsCare systemIncreasing cognitive impairmentMain OutcomesCOVID-19Hospital dischargePrimary outcomeAssociations of Social Support With Physical and Mental Health Symptom Burden After COVID-19 Hospitalization Among Older Adults
Lee S, McAvay G, Geda M, Chattopadhyay S, Acampora D, Araujo K, Charpentier P, Gill T, Hajduk A, Cohen A, Ferrante L. Associations of Social Support With Physical and Mental Health Symptom Burden After COVID-19 Hospitalization Among Older Adults. The Journals Of Gerontology Series A 2024, 79: glae092. PMID: 38558166, PMCID: PMC11059296, DOI: 10.1093/gerona/glae092.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCOVID-19FemaleHospitalizationHumansMaleMental HealthMiddle AgedProspective StudiesSARS-CoV-2Social SupportConceptsLow social supportMental health symptomsSocial supportSymptom burdenHealth symptomsFollow-up assessmentCOVID-19 hospitalizationMedical Outcomes Study Social Support SurveyPhysical symptomsAssociation of social supportEdmonton Symptom Assessment SystemPatient Health Questionnaire-4Burden of physical symptomsMental health symptom burdenModified Edmonton Symptom Assessment SystemSocial Support SurveyParticipants' mean ageAssociated with higher burdenSupport SurveyOlder survivorsSymptom managementOlder AdultsMental healthHispanic ethnicityLongitudinal associations
2022
Rationale, Design, and Characteristics of the VALIANT (COVID‐19 in Older Adults: A Longitudinal Assessment) Cohort
Cohen A, McAvay G, Geda M, Chattopadhyay S, Lee S, Acampora D, Araujo K, Charpentier P, Gill T, Hajduk A, Ferrante L. Rationale, Design, and Characteristics of the VALIANT (COVID‐19 in Older Adults: A Longitudinal Assessment) Cohort. Journal Of The American Geriatrics Society 2022, 71: 832-844. PMID: 36544250, PMCID: PMC9877652, DOI: 10.1111/jgs.18146.Peer-Reviewed Original ResearchMeSH KeywordsAftercareAgedCOVID-19FemaleHospitalizationHumansMalePatient DischargeProspective StudiesConceptsPatient-centered outcomesCOVID-19 hospitalizationCognitive impairmentPhysical functionOlder COVID-19 survivorsCOVID-19-related symptomsCOVID-19Older adultsIntensive care unitCOVID-19 survivorsPersistent cognitive impairmentSix-month followMost older adultsThird of participantsElectronic health recordsStepdown unitAcute illnessBurdensome symptomsCare unitSupplemental oxygenMedian lengthProspective studyMean ageBlack raceBaseline interview
1999
A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
Inouye S, Bogardus S, Charpentier P, Leo-Summers L, Acampora D, Holford T, Cooney L. A Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients. New England Journal Of Medicine 1999, 340: 669-676. PMID: 10053175, DOI: 10.1056/nejm199903043400901.Peer-Reviewed Original ResearchConceptsSeverity of deliriumRisk factorsCognitive impairmentRecurrence rateIntervention groupRisk factor intervention strategyHearing impairmentVisual impairmentHospitalized Older PatientsPatients 70 yearsPrevention of deliriumUsual care unitsUsual care groupGeneral medicine serviceEffective treatment strategiesDuration of episodesPrevent DeliriumOlder patientsRate of usePrimary outcomeSleep medicationPoor outcomePrimary preventionPatient's deliriumTeaching hospital
1993
Predictors of Formal Home Health Care Use in Elderly Patients after Hospitalization
Solomon D, Wagner D, Marenberg M, Acampora D, Cooney L, Inouye S. Predictors of Formal Home Health Care Use in Elderly Patients after Hospitalization. Journal Of The American Geriatrics Society 1993, 41: 961-966. PMID: 8409182, DOI: 10.1111/j.1532-5415.1993.tb06762.x.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAge FactorsAgedAged, 80 and overComorbidityConfidence IntervalsEducational StatusFemaleForecastingGeriatric AssessmentHealth PlanningHealth Services ResearchHome Care ServicesHospitalizationHumansMalePatient DischargePatient ReadmissionProportional Hazards ModelsProspective StudiesRisk FactorsSeverity of Illness IndexSocial SupportConceptsHome health care useHealth care useRisk factorsAcute careElderly patientsSurgical patientsCare useHHC useProspective cohort studyRisk factor presentUniversity Teaching HospitalCohort studyHospital dischargeMedian durationIndependent predictorsSurgical wardsRisk strataDischarge planningTeaching hospitalInstrumental activitiesDaily livingElderly populationHHC agenciesStudy catchment areaPatients
1989
New Epidemiologic Evidence Confirming That Bias Does Not Explain the Aspirin/Reye's Syndrome Association
Forsyth B, Horwitz R, Acampora D, Shapiro E, Viscoli C, Feinstein A, Henner R, Holabird N, Jones B, Karabelas A, Kramer M, Miclette M, Wells J. New Epidemiologic Evidence Confirming That Bias Does Not Explain the Aspirin/Reye's Syndrome Association. JAMA 1989, 261: 2517-2524. PMID: 2704111, DOI: 10.1001/jama.1989.03420170061031.Peer-Reviewed Original ResearchConceptsSyndrome AssociationCase subjectsMedical record review studyRecord review studyCase-control studyNew epidemiologic evidencePotential recall biasSeverity of symptomsEpidemiologic evidenceReye's syndromeEpidemiologic investigationsControl groupDiagnostic biasSusceptibility biasRecall biasBiphasic patternSyndromeAssociationReview studyPotential sourceSubjectsAspirinHospitalIllnessSymptoms
1988
Relation of peak creatine kinase levels during acute myocardial infarction to presence or absence of previous manifestations of myocardial ischemia (angina pectoris or healed myocardial infarction)
Brush J, Brand D, Acampora D, Goldman J, Cabin H. Relation of peak creatine kinase levels during acute myocardial infarction to presence or absence of previous manifestations of myocardial ischemia (angina pectoris or healed myocardial infarction). The American Journal Of Cardiology 1988, 62: 534-537. PMID: 3414544, DOI: 10.1016/0002-9149(88)90650-9.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngina PectorisCreatine KinaseFemaleHospitalizationHumansMaleMiddle AgedMyocardial InfarctionRecurrenceConceptsAcute myocardial infarctionPositive history groupCK-MB levelsPeak CK-MB levelPeak creatine kinase levelPrevious anginaCreatine kinase levelsMyocardial infarctionKinase levelsMean peak creatine kinase levelPrevious coronary artery bypassRecent acute myocardial infarctionCoronary artery bypassBeta-blocking agentsLarge myocardial infarctionHistory groupHigher peak CKArtery bypassHospital complicationsStreptokinase administrationMyocardial ischemiaPeak CKAnginaPrevious historyPatients
1987
Sensitivity of routine clinical criteria for diagnosing myocardial infarction within 24 hours of hospitalization.
Lee T, Rouan G, Weisberg M, Brand D, Cook E, Acampora D, Goldman L. Sensitivity of routine clinical criteria for diagnosing myocardial infarction within 24 hours of hospitalization. Annals Of Internal Medicine 1987, 106: 181-6. PMID: 3800180, DOI: 10.7326/0003-4819-106-2-181.Peer-Reviewed Original ResearchConceptsRecurrent ischemic painHours of admissionMyocardial infarctionIschemic painChest painEnzyme abnormalitiesDiagnostic criteriaRecurrent chest painAcute chest painHours of hospitalizationIntermediate care unitRoutine clinical criteriaCare unitClinical criteriaCommunity hospitalInfarctionPainPatientsEnzyme testingAdmissionAbnormalitiesIndependent testing setHoursSufficient periodHospitalization