2020
Autopsy Services and Emergency Preparedness of a Tertiary Academic Hospital Mortuary for the COVID-19 Public Health Emergency: The Yale Plan
McGuone D, Sinard J, Gill JR, Masters A, Liu C, Morotti R, Parkash V. Autopsy Services and Emergency Preparedness of a Tertiary Academic Hospital Mortuary for the COVID-19 Public Health Emergency: The Yale Plan. Advances In Anatomic Pathology 2020, 27: 355-362. PMID: 32649315, DOI: 10.1097/pap.0000000000000274.Peer-Reviewed Original ResearchConceptsAcute respiratory syndrome coronavirus 2 pandemicSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemicHealth care worker safetyCoronavirus 2 pandemicCOVID-19 public health emergencyHigh-quality patient carePublic health emergencyCorona Virus DiseaseEarly response phaseInfection controlPatient careTissue retrievalAutopsy serviceMortuary servicesHospital mortuaryAutopsiesHealth emergencyPatient flowNovel diseaseVirus diseasePlateau phaseDiseasePandemicRecent memoryEmergency preparedness
2017
Ophthalmic Diseases
Stemmer-Rachamimov A, Laver N, McGuone D, Shah B, Weinstein G, Bedi H. Ophthalmic Diseases. 2017, 462-474. DOI: 10.1017/9781139696401.020.Peer-Reviewed Original ResearchSoft tissue diseaseSpinal cord diseaseNervous system diseasesTissue diseaseCord diseaseSystem diseasesRadiologic techniquesBrain tumorsCongenital malformationsDisease processMultidisciplinary teamAccurate diagnosisOphthalmic diseasesDiseaseSkeletal muscleNeuropathologyNeurologistsTumorsMalformationsAbsence of Alzheimer Disease Neuropathologic Changes in Eyes of Subjects With Alzheimer Disease
Williams EA, McGuone D, Frosch MP, Hyman BT, Laver N, Stemmer-Rachamimov A. Absence of Alzheimer Disease Neuropathologic Changes in Eyes of Subjects With Alzheimer Disease. Journal Of Neuropathology & Experimental Neurology 2017, 76: 376-383. PMID: 28379416, PMCID: PMC7191616, DOI: 10.1093/jnen/nlx020.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseMacular degenerationΒ-amyloidAlzheimer's disease neuropathologic changeAD-related changesAge-matched controlsEyes of subjectsAD-related featuresSeverity of changesAlzheimer changesNeuropathologic changesPathologic findingsAutopsy casesVisual deficitsCommon causeTDP-43Pathology studiesTau proteinExtracellular depositionΑ-synucleinIntracellular accumulationBrainSimilar changesDegenerationDisease
2013
Studying synapses in human brain with array tomography and electron microscopy
Kay KR, Smith C, Wright AK, Serrano-Pozo A, Pooler AM, Koffie R, Bastin ME, Bak TH, Abrahams S, Kopeikina KJ, McGuone D, Frosch MP, Gillingwater TH, Hyman BT, Spires-Jones TL. Studying synapses in human brain with array tomography and electron microscopy. Nature Protocols 2013, 8: 1366-1380. PMID: 23787894, PMCID: PMC3712649, DOI: 10.1038/nprot.2013.078.Peer-Reviewed Original ResearchConceptsHuman brainClinicopathological correlationArray tomographySynapse densityPostmortem studiesPsychiatric illnessClinical cohortAutopsy tissueBrain bankingThousands of synapsesNeurodegenerative diseasesSynapsesUltrastructural studySerial sectionsSynapse levelHuman samplesDiseaseBrainDevelopmental diseasesTomographyLight microscopyUltrathin serial sectionsCohortIllnessPotent way