2023
Breast Cancer Mode of Detection in a Population-Based Cohort
Basappa S, Finney Rutten L, Hruska C, Olson J, Jacobson D, Rhodes D. Breast Cancer Mode of Detection in a Population-Based Cohort. Mayo Clinic Proceedings 2023, 98: 278-289. PMID: 36737116, PMCID: PMC9907001, DOI: 10.1016/j.mayocp.2022.10.010.Peer-Reviewed Original ResearchConceptsPopulation-based cohortBreast cancerAdvanced cancerBreast densityRetrospective medical record reviewDense breastsPositive lymph nodesFirst-time diagnosisRochester Epidemiology ProjectMedical record reviewStage of diseaseLarger tumor sizeWomen age 40High-grade tumorsMultiple logistic regressionYears of ageLymph nodesRecord reviewTumor characteristicsTumor sizeCancer characteristicsCancer modeAge 40Clinical attentionCancer
2021
Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study.
Hruska CB, Geske JR, Conners AL, Whaley DH, Rhodes DJ, O'Connor MK, Carter RE, Scott CG, Vachon CM. Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study. American Journal Of Roentgenology 2021, 216: 1193-1204. PMID: 32755210, PMCID: PMC8640999, DOI: 10.2214/ajr.20.23854.Peer-Reviewed Original ResearchConceptsBackground parenchymal uptakeMolecular breast imagingPostmenopausal womenBreast cancer riskAbsolute riskBreast cancerCohort studyDiscriminatory accuracyDense breastsRisk factorsParenchymal uptakeCancer riskRisk scoreFuture breast cancer diagnosisGreater breast cancer riskBreast cancer risk factorsCox proportional hazards modelGail risk scoreBreast cancer eventsIndependent risk factorSubset of womenCancer risk factorsCase-control studyProportional hazards modelBreast cancer diagnosis
2020
Effect of a 12-Week Pilates Pelvic Floor-Strengthening Program on Short-Term Measures of Stress Urinary Incontinence in Women: A Pilot Study
Hein JT, Rieck TM, Dunfee HA, Johnson DP, Ferguson JA, Rhodes DJ. Effect of a 12-Week Pilates Pelvic Floor-Strengthening Program on Short-Term Measures of Stress Urinary Incontinence in Women: A Pilot Study. Journal Of Alternative And Complementary Medicine 2020, 26: 158-161. PMID: 31916840, PMCID: PMC7044776, DOI: 10.1089/acm.2019.0330.Peer-Reviewed Original Research
2019
Behavioral and psychological impact of returning breast density results to Latinas: study protocol for a randomized clinical trial
Patel BK, Ridgeway JL, Ghosh K, Rhodes DJ, Borah B, Jenkins S, Suman VJ, Norman A, Jewett M, Singh D, Vachon CM, Radecki Breitkopf C. Behavioral and psychological impact of returning breast density results to Latinas: study protocol for a randomized clinical trial. Trials 2019, 20: 744. PMID: 31852492, PMCID: PMC6921571, DOI: 10.1186/s13063-019-3939-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnxietyBreast DensityBreast NeoplasmsEarly Detection of CancerFemaleHealth CommunicationHealth Knowledge, Attitudes, PracticeHealth LiteracyHispanic or LatinoHumansMammographyMass ScreeningMiddle AgedPatient CompliancePatient Education as TopicQualitative ResearchRandomized Controlled Trials as TopicConceptsRandomized clinical trialsMammographic breast densityLimited resource settingsClinical trialsHealth literacyBreast densityWHO Trial Registration Data SetLatina womenTrial Registration Data SetLimited health literacyLow health literacyBreast cancer riskCancer risk communicationPsychological outcomesMeasurement time pointsDiagnostic delayCancer mortalityBackgroundBreast cancerCommon cancerMammogram resultsStudy protocolCommunity clinicsBreast cancerMammography screeningCancer riskDose Reduction in Molecular Breast Imaging With a New Image-Processing Algorithm.
Tao AT, Hruska CB, Conners AL, Hunt KN, Swanson TN, Tran TD, Manduca A, Borges L, Maidment ADA, Lake D, Johnson MP, Carter RE, Rhodes DJ, O'Connor MK. Dose Reduction in Molecular Breast Imaging With a New Image-Processing Algorithm. American Journal Of Roentgenology 2019, 214: 185-193. PMID: 31593516, DOI: 10.2214/ajr.19.21582.Peer-Reviewed Original Research
2018
Quantitative background parenchymal uptake on molecular breast imaging and breast cancer risk: a case-control study
Hruska CB, Geske JR, Swanson TN, Mammel AN, Lake DS, Manduca A, Conners AL, Whaley DH, Scott CG, Carter RE, Rhodes DJ, O’Connor M, Vachon CM. Quantitative background parenchymal uptake on molecular breast imaging and breast cancer risk: a case-control study. Breast Cancer Research 2018, 20: 46. PMID: 29871661, PMCID: PMC5989426, DOI: 10.1186/s13058-018-0973-3.Peer-Reviewed Original Research
2017
Patient Acceptance of Half-dose Vs. Half-time Molecular Breast Imaging
Swanson TN, Tran TD, Hruska CB, Solberg CM, Rhodes DJ, Hunt KN, Conners AL, O'Connor MK. Patient Acceptance of Half-dose Vs. Half-time Molecular Breast Imaging. Journal Of Medical Imaging And Radiation Sciences 2017, 49: 39-43. PMID: 30479286, DOI: 10.1016/j.jmir.2017.08.003.Peer-Reviewed Original ResearchConceptsMolecular breast imagingExact testFisher's exact testDuration of examinationBreast imagingPatients' opinionsPatient acceptanceDose reductionExamination comfortMost womenPatient comfortFemale volunteersRadiation doseExamination typesDoseExamination preferencesImagingPatientsGroupNumber of strategiesSurvey responsesVolunteersWomen
2016
Background parenchymal uptake on molecular breast imaging as a breast cancer risk factor: a case-control study
Hruska CB, Scott CG, Conners AL, Whaley DH, Rhodes DJ, Carter RE, O’Connor M, Hunt KN, Brandt KR, Vachon CM. Background parenchymal uptake on molecular breast imaging as a breast cancer risk factor: a case-control study. Breast Cancer Research 2016, 18: 42. PMID: 27113363, PMCID: PMC4845425, DOI: 10.1186/s13058-016-0704-6.Peer-Reviewed Original ResearchConceptsBackground parenchymal uptakeCase-control studyBreast cancer casesRisk factorsBreast cancerCancer casesParenchymal uptakeIncident breast cancer casesBreast cancer risk factorsRetrospective case-control studyDense breastsConditional logistic regression analysisInvasive breast cancer casesPostmenopausal hormone useCancer risk factorsFunctional imaging biomarkersBreast cancer riskLogistic regression analysisBI-RADS densityPostmenopausal womenEligible womenMenopausal statusHormone useMedian ageSupplemental screening
2015
Direct-Conversion Molecular Breast Imaging of Invasive Breast Cancer: Imaging Features, Extent of Invasive Disease, and Comparison Between Invasive Ductal and Lobular Histology.
Conners AL, Jones KN, Hruska CB, Geske JR, Boughey JC, Rhodes DJ. Direct-Conversion Molecular Breast Imaging of Invasive Breast Cancer: Imaging Features, Extent of Invasive Disease, and Comparison Between Invasive Ductal and Lobular Histology. American Journal Of Roentgenology 2015, 205: w374-81. PMID: 26295674, PMCID: PMC8900216, DOI: 10.2214/ajr.14.13502.Peer-Reviewed Original ResearchConceptsInvasive breast cancerMolecular breast imagingInvasive tumor fociBreast imaging examinationsTumor fociMolecular breastBreast cancerImaging featuresInvasive diseasePathology reportsImaging examinationsHistologic profileBreast imagingBreast imaging findingsChi-square testLobular histologyHistologic subtypeInvasive DuctalImaging findingsInvasive cancerBenign reasonsInvasive fociTumor appearanceBlinded reviewLesion typeDiagnostic workup and costs of a single supplemental molecular breast imaging screen of mammographically dense breasts.
Hruska CB, Conners AL, Jones KN, O'Connor MK, Moriarty JP, Boughey JC, Rhodes DJ. Diagnostic workup and costs of a single supplemental molecular breast imaging screen of mammographically dense breasts. American Journal Of Roentgenology 2015, 204: 1345-53. PMID: 26001247, PMCID: PMC5036572, DOI: 10.2214/ajr.14.13306.Peer-Reviewed Original ResearchConceptsBenign biopsy rateDiagnostic workupBiopsy rateDense breastsAdditional diagnostic workupCancer detection rateMammography of womenBreast imaging examinationsPositive predictive valueDual-head gamma cameraImaging examinationsPredictive valueMolecular breastBiopsyPatientsWorkupBreastScreening mammographyCancerWomenMammographyMalignancyReference standardGamma cameraDetection rateJournal club: molecular breast imaging at reduced radiation dose for supplemental screening in mammographically dense breasts.
Rhodes DJ, Hruska CB, Conners AL, Tortorelli CL, Maxwell RW, Jones KN, Toledano AY, O'Connor MK. Journal club: molecular breast imaging at reduced radiation dose for supplemental screening in mammographically dense breasts. American Journal Of Roentgenology 2015, 204: 241-51. PMID: 25615744, PMCID: PMC4423604, DOI: 10.2214/ajr.14.13357.Peer-Reviewed Original ResearchConceptsCancer detection rateMolecular breast imagingDense breastsOverall cancer detection rateInvasive cancer detection rateDetection ratePositive predictive valueRadiation dose reductionAsymptomatic womenBilateral cancerDCIS detectionSupplemental screeningInvasive diseaseBiopsy rateDose reductionReduced radiation dosePredictive valueMolecular breastBreastScreening mammographyDiagnostic performanceRadiopharmaceutical activityCancerRadiation doseMammography
2012
Gamma camera breast imaging lexicon.
Conners AL, Maxwell RW, Tortorelli CL, Hruska CB, Rhodes DJ, Boughey JC, Berg WA. Gamma camera breast imaging lexicon. American Journal Of Roentgenology 2012, 199: w767-74. PMID: 23169751, DOI: 10.2214/ajr.11.8298.Peer-Reviewed Original ResearchThe Use of Molecular Breast Imaging to Assess Response in Women Undergoing Neoadjuvant Therapy for Breast Cancer
Wahner-Roedler DL, Boughey JC, Hruska CB, Chen B, Rhodes DJ, Tortorelli CL, Maxwell RW, S. S, O'Connor MK. The Use of Molecular Breast Imaging to Assess Response in Women Undergoing Neoadjuvant Therapy for Breast Cancer. Clinical Nuclear Medicine 2012, 37: 344-350. PMID: 22391702, PMCID: PMC3296091, DOI: 10.1097/rlu.0b013e31824437b3.Peer-Reviewed Original ResearchConceptsMolecular breast imagingNeoadjuvant therapyTumor sizeBreast cancerResidual tumor sizeProspective pilot studyInvasive breast cancerBreast cancer treatmentTumor-specific radiopharmaceuticalsPathologic extentResidual diseasePretreatment valuesTumor responseTumor extentPosttreatment valuesIntravenous injectionPathologic measurementsRadiotracer uptakePredictive valueMolecular breastPatientsCancerCancer treatmentPilot studyInterest analysis
2011
Adherence to Preventive Recommendations: Experience of a Cohort Presenting for Executive Health Care
Shippee ND, Mullan RJ, Nabhan M, Kermott CA, Hagen PT, Rhodes DJ, Montori VM, Murad MH. Adherence to Preventive Recommendations: Experience of a Cohort Presenting for Executive Health Care. Population Health Management 2011, 15: 65-70. PMID: 22092188, DOI: 10.1089/pop.2011.0029.Peer-Reviewed Original ResearchConceptsCancer screeningPreventive servicesOptimal adherence ratesColorectal cancer screeningCervical cancer screeningHealth careMultivariate logistic regressionPredictors of adherencePneumococcal vaccinationTetanus immunizationAdherence ratesPreventive recommendationsHealth behaviorsQuality improvement processDisease preventionLogistic regressionSocioeconomic statusAdherenceImmunizationUse concernsCareUsual barriersScreeningPatientsPresentingRadiologic and Pathologic Images of Mammary Fibromatosis
Brodt JK, Rhodes DJ, Glazebrook KN, Hruska C, O’Connor M, Boughey JC. Radiologic and Pathologic Images of Mammary Fibromatosis. The Breast Journal 2011, 17: 207-209. PMID: 21269344, DOI: 10.1111/j.1524-4741.2010.01061.x.Peer-Reviewed Original Research
2010
Comparison of radiation exposure and associated radiation‐induced cancer risks from mammography and molecular imaging of the breasta)
O'Connor MK, Li H, Rhodes DJ, Hruska CB, Clancy CB, Vetter RJ. Comparison of radiation exposure and associated radiation‐induced cancer risks from mammography and molecular imaging of the breasta). Medical Physics 2010, 37: 6187-6198. PMID: 21302775, PMCID: PMC2997811, DOI: 10.1118/1.3512759.Peer-Reviewed Original ResearchConceptsBenefit/risk ratioMolecular breast imagingCumulative cancer incidenceCancer incidenceRisk ratioAge groupsExcess absolute risk (EAR) modelsAnnual digital mammographyAttributable risk modelRadiation-induced cancer riskBreast cancer incidenceBreast-specific gammaPositron emission mammographyBEIR VII reportRadiation-induced cancerDense breast tissueAbsolute risk modelsMBq FScreening groupAnnual screeningConventional dosesMBq TcLifetime riskBreast cancerAge 40Dedicated Dual-Head Gamma Imaging for Breast Cancer Screening in Women with Mammographically Dense Breasts
Rhodes DJ, Hruska CB, Phillips SW, Whaley DH, O'Connor MK. Dedicated Dual-Head Gamma Imaging for Breast Cancer Screening in Women with Mammographically Dense Breasts. Radiology 2010, 258: 106-18. PMID: 21045179, DOI: 10.1148/radiol.10100625.Peer-Reviewed Original ResearchConceptsPositive predictive valueBreast cancerDense breastsDiagnostic yieldNode-negative breast cancerAdditional risk factorsNumber of patientsGamma imagingNumber of biopsiesBreast cancer screeningHIPAA-compliant protocolIpsilateral cancerAbnormal findingsAsymptomatic womenEligible participantsCancer screeningRisk factorsSestamibi injection
2008
Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors.
Hruska CB, Phillips SW, Whaley DH, Rhodes DJ, O'Connor MK. Molecular breast imaging: use of a dual-head dedicated gamma camera to detect small breast tumors. American Journal Of Roentgenology 2008, 191: 1805-15. PMID: 19020253, PMCID: PMC3885170, DOI: 10.2214/ajr.07.3693.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsEquipment DesignEquipment Failure AnalysisFemaleGamma CamerasHumansImage EnhancementMiddle AgedMolecular Probe TechniquesRadionuclide ImagingRadiopharmaceuticalsReproducibility of ResultsSensitivity and SpecificitySingle-Blind MethodTechnetium Tc 99m SestamibiConceptsMolecular breast imagingMolecular breastBI-RADS category 4Breast imagingMBq of technetiumSmall breast tumorsTelluride gamma cameraGamma cameraSubcentimeter lesionsUptake scoreAdditional cancersBlinded reviewDetection of cancerBreast tumorsLesionsSmall lesionsBreastPatientsBreast lesionsBlinded readersCancerOblique viewCategory 4Mediolateral oblique viewTumors
2007
Molecular Breast Imaging: Advantages and Limitations of a Scintimammographic Technique in Patients with Small Breast Tumors
O'Connor MK, Phillips SW, Hruska CB, Rhodes DJ, Collins DA. Molecular Breast Imaging: Advantages and Limitations of a Scintimammographic Technique in Patients with Small Breast Tumors. The Breast Journal 2007, 13: 3-11. PMID: 17214787, DOI: 10.1111/j.1524-4741.2006.00356.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, Intraductal, NoninfiltratingCarcinoma, LobularCarcinoma, PapillaryFemaleHumansMammographyMiddle AgedPredictive Value of TestsRadionuclide ImagingSensitivity and SpecificityTechnetium Tc 99m SestamibiUltrasonographyConceptsMolecular breast imagingSmall breast tumorsBreast tumorsEvidence of cancerFalse-positive scansLarger patient populationMalignant breast tumorsStandard mammographic viewsMBq TcOccult tumorsPatient populationMalignant tumorsPositive scansPatientsTumorsBreast tissueSubjective discomfortBiopsySurgeryMammographic viewsGamma cameraBreast imagingBreast thicknessPreliminary studyRegular detection
2005
Molecular Breast Imaging: A New Technique Using Technetium Tc 99m Scintimammography to Detect Small Tumors of the Breast
Rhodes DJ, O'Connor MK, Phillips SW, Smith RL, Collins DA. Molecular Breast Imaging: A New Technique Using Technetium Tc 99m Scintimammography to Detect Small Tumors of the Breast. Mayo Clinic Proceedings 2005, 80: 24-30. DOI: 10.4065/80.1.24.Peer-Reviewed Original ResearchConceptsMolecular breast imagingMalignant lesionsTechnetium TcBreast parenchymaEvidence of cancerTrue-negative scansFalse-positive scansSensitivity of mammographyTelluride gamma cameraMagnetic resonance imagingTrue positive casesMalignant breast lesionsGamma cameraFat necrosisFalse-positive resultsSmall cancersAdditional lesionsDetection of lesionsSmall tumorsPatientsBenign fibroadenomasLesionsResonance imagingBreast contralateralSurgery