1992
Changes in T-Lymphocyte Subsets in Intravenous Drug Users With HIV-1 Infection
Margolick J, Muñoz A, Vlahov D, Solomon L, Astemborski J, Cohn S, Nelson K. Changes in T-Lymphocyte Subsets in Intravenous Drug Users With HIV-1 Infection. JAMA 1992, 267: 1631-1636. PMID: 1347321, DOI: 10.1001/jama.1992.03480120069035.Peer-Reviewed Original ResearchConceptsSeropositive intravenous drug usersIntravenous drug usersHIV-1 infectionHIV-1-seropositive intravenous drug usersDrug usersCell countSeronegative intravenous drug usersHuman immunodeficiency virus type 1Complete blood cell countImmunodeficiency virus type 1Absolute numberCD4 cell countCD4 lymphocyte countPercentage of CD4T lymphocyte subsetsCD8 T cellsT cell subsetsCommunity-based clinicsBlood cell countTime of seroconversionVirus type 1Multivariate regression analysisUse of drugsCD4 lymphocytesCD8 lymphocytesPrevalence of Tuberculin Positivity and Skin Test Anergy in HIV-1—Seropositive and —Seronegative Intravenous Drug Users
Graham N, Nelson K, Solomon L, Bonds M, Rizzo R, Scavotto J, Astemborski J, Vlahov D. Prevalence of Tuberculin Positivity and Skin Test Anergy in HIV-1—Seropositive and —Seronegative Intravenous Drug Users. JAMA 1992, 267: 369-373. PMID: 1727959, DOI: 10.1001/jama.1992.03480030047035.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHIV-1 seropositivesSkin test anergyHIV-1 seropositive groupSeronegative intravenous drug usersTuberculin positivityLymphocyte countPPD positivityHIV-1-seropositive intravenous drug usersPPD tuberculinDrug usersHuman immunodeficiency virus serostatusSeropositive intravenous drug usersHIV-1 seropositive patientsTuberculin skin test resultsHIV-1 seronegativeHIV-1 seronegativesPPD test resultsHIV-1 seropositivityDelayed-type hypersensitivityCommunity-based cohortSkin test resultsYears of agePositive test resultsInverse linear trendPrognostic indicators for development of AIDS among intravenous drug users.
Muñoz A, Vlahov D, Solomon L, Margolick J, Bareta J, Cohn S, Astemborski J, Nelson K. Prognostic indicators for development of AIDS among intravenous drug users. JAIDS Journal Of Acquired Immune Deficiency Syndromes 1992, 5: 694-700. PMID: 1613668.Peer-Reviewed Original ResearchConceptsCD4 cell countIntravenous drug usersClinical symptomsDrug usersCell countHigher CD4 cell countsHIV-1-related symptomsSeropositive intravenous drug usersPneumocystis carinii prophylaxisIntravenous drug useDevelopment of AIDSDose-response relationshipYear of enrollmentSerum neopterinLaboratory markersSerum betaPrognostic indicatorClinical evaluationAntiviral agentsRelative hazardDrug useSurvival analysisMultivariate analysisSignificant associationAIDS
1991
Utilization of health services in a cohort of intravenous drug users with known HIV-1 serostatus.
Solomon L, Frank R, Vlahov D, Astemborski J. Utilization of health services in a cohort of intravenous drug users with known HIV-1 serostatus. American Journal Of Public Health 1991, 81: 1285-90. PMID: 1928527, PMCID: PMC1405342, DOI: 10.2105/ajph.81.10.1285.Peer-Reviewed Original ResearchConceptsIntravenous drug usersCD4 cell countDrug usersHealth servicesHIV serostatusClinical symptomsHIV-seropositive intravenous drug usersHealth insuranceCell countAsymptomatic HIV-1 infectionSeropositive intravenous drug usersHuman immunodeficiency virus (HIV) infectionHIV-seropositive drug usersOngoing natural history studyLow CD4 countHIV-1 seropositiveImmunodeficiency virus infectionHIV-1 serostatusHealth care utilizationHIV-1 infectionHIV-positive serostatusNatural history studiesHealth care servicesCD4 countMore HIV