2018
Aldehyde Dehydrogenases☆
Vasiliou V, Thompson D, Petersen D. Aldehyde Dehydrogenases☆. 2018, 146-163. DOI: 10.1016/b978-0-12-801238-3.99183-9.Peer-Reviewed Original ResearchAldehyde dehydrogenasesAldehyde dehydrogenase geneType II hyperprolinemiaTransgenic knockout mouse modelKnockout mouse modelHuman genomeHigh aldehyde dehydrogenase (ALDH) activityDehydrogenase geneExogenous aldehydesCancer stem cellsMolecular basisPhysiological processesDependent enzymesAldehyde dehydrogenase activityMicrophthalmia/anophthalmiaAldehyde dehydrogenaseStem cellsOxidative damageDehydrogenasesSjögren-Larsson syndromeGenesDehydrogenase activityLate-onset Alzheimer's diseasePivotal roleOxidation of aldehydes
2012
Aldehyde dehydrogenases: From eye crystallins to metabolic disease and cancer stem cells
Vasiliou V, Thompson DC, Smith C, Fujita M, Chen Y. Aldehyde dehydrogenases: From eye crystallins to metabolic disease and cancer stem cells. Chemico-Biological Interactions 2012, 202: 2-10. PMID: 23159885, PMCID: PMC4128326, DOI: 10.1016/j.cbi.2012.10.026.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAldehyde dehydrogenaseHuman ALDH genesALDH gene familyNon-catalytic activitiesEukaryotic genomesGene familyALDH genesCancer stem cellsMolecular basisDependent enzymesStem cellsAldehyde metabolismOxidative stressNicotinamide adenine dinucleotideOxidation of aldehydesPathophysiological processesAdenine dinucleotideDehydrogenaseMetabolic diseasesGenomeImportant roleEmbryogenesisGenesStructural elementsCrystallins