2014
Coenzyme Q10 and immunity: A case report and new implications for treatment of recurrent infections in metabolic diseases
Farough S, Karaa A, Walker M, Slate N, Dasu T, Verbsky J, Fusunyan R, Canapari C, Kinane T, Van Cleave J, Sweetser D, Sims K, Walter J. Coenzyme Q10 and immunity: A case report and new implications for treatment of recurrent infections in metabolic diseases. Clinical Immunology 2014, 155: 209-212. PMID: 25264263, DOI: 10.1016/j.clim.2014.09.010.Peer-Reviewed Original ResearchConceptsRecurrent infectionsCoQ10 deficiencyImmunoglobulin replacement therapyFour-year-old girlCoenzyme Q10 deficiencyImmune dysfunctionImmune dysregulationReplacement therapyCase reportIsolated myopathyImmune functionMetabolic diseasesOld girlCoenzyme Q10Developmental delayInfectionDiseaseDeficiencyDysfunctionHypotoniaTherapyMyopathyImmunity
2011
A pilot study to identify pre- and peri-operative risk factors for airway complications following adenotonsillectomy for treatment of severe pediatric OSA
Hill CA, Litvak A, Canapari C, Cummings B, Collins C, Keamy DG, Ferris TG, Hartnick CJ. A pilot study to identify pre- and peri-operative risk factors for airway complications following adenotonsillectomy for treatment of severe pediatric OSA. International Journal Of Pediatric Otorhinolaryngology 2011, 75: 1385-1390. PMID: 21871668, DOI: 10.1016/j.ijporl.2011.07.034.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdenoidectomyAge FactorsChildChild, PreschoolCohort StudiesFemaleFollow-Up StudiesHumansMalePatient SelectionPilot ProjectsPostoperative CarePostoperative ComplicationsPredictive Value of TestsPreoperative CareRecurrenceRegression AnalysisRetrospective StudiesRisk AssessmentSeverity of Illness IndexSleep Apnea, ObstructiveTime FactorsTonsillectomyTreatment OutcomeConceptsPeri-operative risk factorsApnea-hypopnea indexPost-operative complicationsRisk factorsAirway complicationsSevere OSAComplication rateProspective studyPilot studyFuture prospective validation studiesTertiary care academic institutionPost-operative morbidityProspective validation studyBest-practice algorithmsPediatric OSAMinor complicationsRetrospective reviewPotential significant cost savingsICU settingPediatric floorOxygen saturationComplicationsPractice algorithmAdenotonsillectomyRoom airRelationship between sleep apnea, fat distribution, and insulin resistance in obese children.
Canapari CA, Hoppin AG, Kinane TB, Thomas BJ, Torriani M, Katz ES. Relationship between sleep apnea, fat distribution, and insulin resistance in obese children. Journal Of Clinical Sleep Medicine 2011, 7: 268-73. PMID: 21677896, PMCID: PMC3113965, DOI: 10.5664/jcsm.1068.Peer-Reviewed Original ResearchConceptsObstructive sleep apneaHomeostasis model assessmentBody mass indexLog homeostasis model assessmentBMI z-scoreObese childrenInsulin resistanceFat distributionSleep apneaMean body mass indexSubcutaneous adipose tissue areaZ-scoreVisceral fat areaVisceral fat distributionSubset of patientsAdipose tissue areaPediatric obesity clinicSubset of subjectsMagnetic resonance imagingOSA pathogenesisObesity clinicOSA severityObese subjectsMass indexFat area