2012
IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine
Huber S, Gagliani N, Zenewicz LA, Huber FJ, Bosurgi L, Hu B, Hedl M, Zhang W, O’Connor W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Booth CJ, Cho JH, Ouyang W, Abraham C, Flavell RA. IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine. Nature 2012, 491: 259-263. PMID: 23075849, PMCID: PMC3493690, DOI: 10.1038/nature11535.Peer-Reviewed Original Research
2000
A Vitamin D3 Analog Induces a G1-Phase Arrest in CaCo-2 Cells by Inhibiting Cdk2 and Cdk6: Roles of Cyclin E, p21Waf1, and p27Kip1**This work was supported by National Institutes of Health Grants DK-39573, CA-36745 (to T.A.B. and M.B.) and P30DK42086 (to T.A.B., Digestive Disease Research Core Center).
Scaglione-Sewell B, Bissonnette M, Skarosi S, Abraham C, Brasitus T. A Vitamin D3 Analog Induces a G1-Phase Arrest in CaCo-2 Cells by Inhibiting Cdk2 and Cdk6: Roles of Cyclin E, p21Waf1, and p27Kip1**This work was supported by National Institutes of Health Grants DK-39573, CA-36745 (to T.A.B. and M.B.) and P30DK42086 (to T.A.B., Digestive Disease Research Core Center). Endocrinology 2000, 141: 3931-3939. DOI: 10.1210/en.141.11.3931.Peer-Reviewed Original ResearchF6-D3Caco-2 cellsActivity of cyclin-dependent kinase 2Azoxymethane model of colon cancerCaco-2Colon cancerModel of colon cancerCyclin EChemopreventive actionTransforming growth factor-bCyclin-dependent kinase 2Human colon adenocarcinoma cell lineAntibody neutralization studiesColon adenocarcinoma cell lineDevelopment of colon adenocarcinomaVitamin D3 analogsHuman colonic epitheliumHuman colon cancerCyclin-dependent kinasesGrowth factor BRats treated with azoxymethaneExpression of cyclin EAdenocarcinoma cell lineAzoxymethane modelCell cycle arrest