2020
Gray matter volumetric correlates of behavioral activation and inhibition system traits in children: An exploratory voxel-based morphometry study of the ABCD project data
Ide JS, Li HT, Chen Y, Le TM, Li CSP, Zhornitsky S, Li CR. Gray matter volumetric correlates of behavioral activation and inhibition system traits in children: An exploratory voxel-based morphometry study of the ABCD project data. NeuroImage 2020, 220: 117085. PMID: 32592852, PMCID: PMC7572877, DOI: 10.1016/j.neuroimage.2020.117085.Peer-Reviewed Original ResearchConceptsBehavioral activation systemBehavioral inhibition systemGray matter volumeHigher BAS scoresVentral striatumBAS scoresInhibition systemBIS scoresInferior frontal cortexFundamental behavioral traitsTwins/siblingsRight anterior insulaHigher BIS scoresNeural correlatesDevelopmental neuroscienceAnterior insulaVolumetric correlatesVoxel-based morphometry studyInternalizing psychopathologyCerebral basisVoxel-based morphometryBehavioral activationVentral caudateAvoidance traitsMatter volume
2018
Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects
Mackey S, Allgaier N, Chaarani B, Spechler P, Orr C, Bunn J, Allen NB, Alia-Klein N, Batalla A, Blaine S, Brooks S, Caparelli E, Chye YY, Cousijn J, Dagher A, Desrivieres S, Feldstein-Ewing S, Foxe JJ, Goldstein RZ, Goudriaan AE, Heitzeg MM, Hester R, Hutchison K, Korucuoglu O, Li CR, London E, Lorenzetti V, Luijten M, Martin-Santos R, May A, Momenan R, Morales A, Paulus MP, Pearlson G, Rousseau ME, Salmeron BJ, Schluter R, Schmaal L, Schumann G, Sjoerds Z, Stein DJ, Stein EA, Sinha R, Solowij N, Tapert S, Uhlmann A, Veltman D, van Holst R, Whittle S, Wiers R, Wright M, Yücel M, Zhang S, Yurgelun-Todd D, Hibar D, Jahanshad N, Evans A, Thompson P, Glahn D, Conrod P, Garavan H. Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects. American Journal Of Psychiatry 2018, 176: 119-128. PMID: 30336705, PMCID: PMC6427822, DOI: 10.1176/appi.ajp.2018.17040415.Peer-Reviewed Original ResearchConceptsRegional brain volumesControl subjectsSubstance dependenceBrain volumeBrain regionsLower brain volumeAlcohol use disorderGray matter volumeTotal intracranial volumeMedial orbitofrontal cortexCommon neural substrateCortical thicknessUse disordersUseful biomarkerMatter volumeSubcortical volumesImaging biomarkersAlcohol dependenceIntracranial volumeOrbitofrontal cortexRegional volumesBrain structuresRelevant imaging biomarkersLow volumeNeural substratesDecreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement
Yu T, Li Y, Fan F, Cao H, Luo X, Tan S, Yang F, Zhang X, Shugart YY, Hong LE, Li CR, Tan Y. Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement. Scientific Reports 2018, 8: 12884. PMID: 30150749, PMCID: PMC6110787, DOI: 10.1038/s41598-018-31186-y.Peer-Reviewed Original ResearchConceptsGray matter volumeAbnormal Involuntary Movement ScaleTardive dyskinesiaMatter volumeTD severityAntipsychotic medication treatmentCerebral morphological changesAbnormal involuntary movementsBrain structural magnetic resonance imagesPsychopathological symptomsNegative Syndrome ScaleNon-TD groupVoxel-based morphometryMedication treatmentHealthy controlsGMV changesMotor disordersAIMS scoresInvoluntary movementsMovement ScaleStructural magnetic resonance imagesTemporal cortexSchizophrenia patientsLingual gyrusSyndrome Scale
2013
Effects of Androgen Deprivation on Cerebral Morphometry in Prostate Cancer Patients – An Exploratory Study
Chao HH, Hu S, Ide JS, Uchio E, Zhang S, Rose M, Concato J, Li CS. Effects of Androgen Deprivation on Cerebral Morphometry in Prostate Cancer Patients – An Exploratory Study. PLOS ONE 2013, 8: e72032. PMID: 23977199, PMCID: PMC3747074, DOI: 10.1371/journal.pone.0072032.Peer-Reviewed Original ResearchConceptsAndrogen deprivation therapyProstate cancer patientsGray matter volumeMagnetic resonance imagingPrimary motor cortexCancer patientsVoxel-based morphometryMatter volumeMotor cortexProstate cancerEffects of ADTLow-risk prostate cancerCerebral gray matter volumeStatistical Parametric Mapping 8Utility of brainControl participantsHigh-resolution magnetic resonance imagingPotential side effectsQuality of lifeResolution magnetic resonance imagingSame time pointsFunctional magnetic resonance imagingHigh-resolution T1Prefrontal cortical activationDorsolateral prefrontal cortex
2010
Association of Frontal and Posterior Cortical Gray Matter Volume With Time to Alcohol Relapse: A Prospective Study
Rando K, Hong KI, Bhagwagar Z, Li CS, Bergquist K, Guarnaccia J, Sinha R. Association of Frontal and Posterior Cortical Gray Matter Volume With Time to Alcohol Relapse: A Prospective Study. American Journal Of Psychiatry 2010, 168: 183-192. PMID: 21078704, PMCID: PMC3668974, DOI: 10.1176/appi.ajp.2010.10020233.Peer-Reviewed Original ResearchConceptsGray matter volume deficitsGray matter volumeAlcohol-dependent patientsMatter volumeVolume deficitsAlcohol relapseRelapse riskComparison subjectsBrain regionsCortical gray matter volumeAlcohol useRegional brain volume differencesSmaller gray matter volumePoor clinical outcomeBrain volume deficitsFrontal gray matter volumeGray matter atrophyAbstinent alcohol-dependent patientsAlcoholism treatment outcomeHigh-resolution structural MRIProspective study designHealthy comparison subjectsVoxel-based morphometryAlcohol-dependent groupMonths of abstinence