2018
Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement
Yu T, Li Y, Fan F, Cao H, Luo X, Tan S, Yang F, Zhang X, Shugart YY, Hong LE, Li CR, Tan Y. Decreased Gray Matter Volume of Cuneus and Lingual Gyrus in Schizophrenia Patients with Tardive Dyskinesia is Associated with Abnormal Involuntary Movement. Scientific Reports 2018, 8: 12884. PMID: 30150749, PMCID: PMC6110787, DOI: 10.1038/s41598-018-31186-y.Peer-Reviewed Original ResearchConceptsGray matter volumeAbnormal Involuntary Movement ScaleTardive dyskinesiaMatter volumeTD severityAntipsychotic medication treatmentCerebral morphological changesAbnormal involuntary movementsBrain structural magnetic resonance imagesPsychopathological symptomsNegative Syndrome ScaleNon-TD groupVoxel-based morphometryMedication treatmentHealthy controlsGMV changesMotor disordersAIMS scoresInvoluntary movementsMovement ScaleStructural magnetic resonance imagesTemporal cortexSchizophrenia patientsLingual gyrusSyndrome ScaleResting-state Brain Activity Changes Associated with Tardive Dyskinesia in Patients with Schizophrenia: Fractional Amplitude of Low-frequency Fluctuation Decreased in the Occipital Lobe
Zhang P, Li Y, Fan F, Li CR, Luo X, Yang F, Yao Y, Tan Y. Resting-state Brain Activity Changes Associated with Tardive Dyskinesia in Patients with Schizophrenia: Fractional Amplitude of Low-frequency Fluctuation Decreased in the Occipital Lobe. Neuroscience 2018, 385: 237-245. PMID: 29909076, DOI: 10.1016/j.neuroscience.2018.06.014.Peer-Reviewed Original ResearchConceptsAbnormal Involuntary Movement ScaleMiddle occipital gyrusRight calcarine sulcusTardive dyskinesiaBrain activity changesClinical parametersLeft middle occipital gyrusSchizophrenic patientsCalcarine sulcusOccipital lobeSeverity of TDAIMS total scoreDecreased brain activityFractional amplitudeResting-state functional magnetic resonance imaging (fMRI) dataResting-state brain activityLow-frequency fluctuationsNegative Syndrome ScaleBrain activityActivity changesConstructional scoresTD groupTD patientsHealthy controlsMagnetic resonance imaging data
2010
Association of Frontal and Posterior Cortical Gray Matter Volume With Time to Alcohol Relapse: A Prospective Study
Rando K, Hong KI, Bhagwagar Z, Li CS, Bergquist K, Guarnaccia J, Sinha R. Association of Frontal and Posterior Cortical Gray Matter Volume With Time to Alcohol Relapse: A Prospective Study. American Journal Of Psychiatry 2010, 168: 183-192. PMID: 21078704, PMCID: PMC3668974, DOI: 10.1176/appi.ajp.2010.10020233.Peer-Reviewed Original ResearchConceptsGray matter volume deficitsGray matter volumeAlcohol-dependent patientsMatter volumeVolume deficitsAlcohol relapseRelapse riskComparison subjectsBrain regionsCortical gray matter volumeAlcohol useRegional brain volume differencesSmaller gray matter volumePoor clinical outcomeBrain volume deficitsFrontal gray matter volumeGray matter atrophyAbstinent alcohol-dependent patientsAlcoholism treatment outcomeHigh-resolution structural MRIProspective study designHealthy comparison subjectsVoxel-based morphometryAlcohol-dependent groupMonths of abstinence