Alexithymia and stress-induced brain activation in cocaine-dependent men and women.
Li CS, Sinha R. Alexithymia and stress-induced brain activation in cocaine-dependent men and women. Journal Of Psychiatry And Neuroscience 2006, 31: 115-21. PMID: 16575427, PMCID: PMC1413961.Peer-Reviewed Original ResearchConceptsToronto Alexithymia ScaleFrontal cortexTAS scoresScript-guided imageryAbstinent cocaine-dependent subjectsBilateral temporal cortexFunctional magnetic resonanceStress-induced brain activationProcessing of stressMiddle frontal cortexCocaine-dependent individualsRight frontal cortexCocaine-dependent menCocaine-dependent patientsNeutral imageryNeural processingBrain activationMale cocaine usersStressful situationsCocaine-dependent subjectsRight amygdalaAlexithymic featuresAlexithymia ScaleTemporal cortexSubcortical activationAntisocial personality and stress-induced brain activation in cocaine-dependent patients
Li CS, Kosten TR, Sinha R. Antisocial personality and stress-induced brain activation in cocaine-dependent patients. Neuroreport 2006, 17: 243-247. PMID: 16462591, DOI: 10.1097/01.wnr.0000199471.06487.a2.Peer-Reviewed Original ResearchConceptsCocaine-dependent individualsDistress processingBrain activationStress imageryAntisocial personalitySocialization scoresFunctional magnetic resonance imaging studyAbstinent cocaine-dependent individualsRegional brain activationStress-induced brain activationFemale participantsMedial prefrontal cortexMagnetic resonance imaging studyResonance imaging studyNeural correlatesLower socialization scoresCocaine-dependent patientsCorticolimbic brain regionsPrefrontal cortexImportant sex differencesBrain regionsPersonalityInterest analysisSignificant activationEffect size