2021
Sex differences in neural responses to reward and the influences of individual reward and punishment sensitivity
Dhingra I, Zhang S, Zhornitsky S, Wang W, Le TM, Li CR. Sex differences in neural responses to reward and the influences of individual reward and punishment sensitivity. BMC Neuroscience 2021, 22: 12. PMID: 33639845, PMCID: PMC7913329, DOI: 10.1186/s12868-021-00618-3.Peer-Reviewed Original ResearchConceptsMonetary incentive delay taskFunctional magnetic resonance imagingNeural responsesSex differencesReward-related brain activationBilateral orbitofrontal cortexMagnetic resonance imagingIncentive delay taskWhole-brain regressionVisual cortexResonance imagingOrbitofrontal cortexBrain activationWomenSuccess rateFMRI studyMenDelay taskImaging literatureNeural sensitivityCortexNeural basisAffective functionsHigher SR scoresLarge wins
2020
Perceived burdensomeness and neural responses to ostracism in the Cyberball task
Le TM, Zhornitsky S, Wang W, Li CR. Perceived burdensomeness and neural responses to ostracism in the Cyberball task. Journal Of Psychiatric Research 2020, 130: 1-8. PMID: 32763557, PMCID: PMC7554229, DOI: 10.1016/j.jpsychires.2020.06.015.Peer-Reviewed Original ResearchConceptsCyberball taskInterpersonal needsIndividual differencesProsocial behaviorNeural responsesSocial interactionStronger neural responsesGreater brain activationDorsomedial prefrontal cortexMiddle frontal gyrusSocial exclusionResponse timeBrain activationBrain correlatesBehavioral performanceFMRI studyAnterior insulaFrontal gyrusSocial painBehavioral avoidanceAffective responsesBehavioral measuresNeural activationPrefrontal cortexEmotional distress
2016
Novelty Seeking, Harm Avoidance, and Cerebral Responses to Conflict Anticipation: An Exploratory Study
Hu J, Hu S, Maisano JR, Chao HH, Zhang S, Li CR. Novelty Seeking, Harm Avoidance, and Cerebral Responses to Conflict Anticipation: An Exploratory Study. Frontiers In Human Neuroscience 2016, 10: 546. PMID: 27857686, PMCID: PMC5093128, DOI: 10.3389/fnhum.2016.00546.Peer-Reviewed Original ResearchInferior parietal lobuleConflict anticipationProactive controlLateral orbitofrontal cortexMiddle frontal gyrusHarm avoidancePre-supplementary motor areaBilateral inferior parietal lobuleRight inferior parietal lobuleCognitive control circuitsWhole-brain linear regressionTrial reaction timeStop-signal taskRegional brain activationRight lateral orbitofrontal cortexCerebral responsesIndividual differencesSignal taskBrain activationFMRI studyTridimensional Personality QuestionnaireFrontal gyrusGreater activationHA traitExploratory study
2015
Individual variation in the neural processes of motor decisions in the stop signal task: the influence of novelty seeking and harm avoidance personality traits
Hu J, Lee D, Hu S, Zhang S, Chao H, Li CS. Individual variation in the neural processes of motor decisions in the stop signal task: the influence of novelty seeking and harm avoidance personality traits. Brain Structure And Function 2015, 221: 2607-2618. PMID: 25989852, PMCID: PMC4654717, DOI: 10.1007/s00429-015-1061-4.Peer-Reviewed Original ResearchConceptsStop-signal taskHarm avoidanceNeural processesSignal taskPersonality traitsStudy of cognitionWhole-brain regressionRegional brain activationRisk-taking processesCognitive controlExecutive controlStop errorBrain activationFMRI studyBehavioral tasksMotor decisionsFrontopolar cortexMonetary rewardsNovelty seekingRisk-taking responsesBilateral orbitofrontalExplicit manipulationDorsomedial prefrontalRegional activationParahippocampal gyrusConflict anticipation in alcohol dependence — A model-based fMRI study of stop signal task
Hu S, Ide JS, Zhang S, Sinha R, Li CS. Conflict anticipation in alcohol dependence — A model-based fMRI study of stop signal task. NeuroImage Clinical 2015, 8: 39-50. PMID: 26106526, PMCID: PMC4473266, DOI: 10.1016/j.nicl.2015.03.008.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeHealthy control individualsConflict anticipationAlcohol dependenceCognitive controlProactive controlSignal taskSequential effectsModel-based fMRI studyAlcohol consumptionStop signalPre-supplementary motor areaBilateral inferior parietal cortexPerigenual anterior cingulate cortexSignificant sequential effectInferior parietal cortexSignal reaction timeWhole-brain responsesAnterior cingulate cortexRecent alcohol consumptionNeural correlatesFMRI studyNeural markersMotor areaTrial onset
2014
Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals
Zhang S, Li CS. Functional Clustering of the Human Inferior Parietal Lobule by Whole-Brain Connectivity Mapping of Resting-State Functional Magnetic Resonance Imaging Signals. Brain Connectivity 2014, 4: 53-69. PMID: 24308753, PMCID: PMC3929139, DOI: 10.1089/brain.2013.0191.Peer-Reviewed Original ResearchConceptsInferior parietal lobuleHuman inferior parietal lobuleParietal lobulePosterior inferior parietal lobuleFunctional magnetic resonance imaging (fMRI) dataResting-state functional magnetic resonance imaging (fMRI) dataInferior frontal gyrusFunctional magnetic resonance imaging (fMRI) signalsEarlier fMRI studiesDefault mode networkSpatial attentionCognitive challengesIntraparietal sulcusFMRI studyMathematical cognitionFrontal gyrusAngular gyrusSupramarginal gyrusHemispheric differencesMode networkMagnetic resonance imaging dataFunctional segregationRegional activationLanguage processingPosterior subregions
2012
Neural Processes of an Indirect Analog of Risk Taking in Young Nondependent Adult Alcohol Drinkers—An fMRI Study of the Stop Signal Task
Bednarski SR, Erdman E, Luo X, Zhang S, Hu S, Li C. Neural Processes of an Indirect Analog of Risk Taking in Young Nondependent Adult Alcohol Drinkers—An fMRI Study of the Stop Signal Task. Alcohol Clinical And Experimental Research 2012, 36: 768-779. PMID: 22339607, PMCID: PMC3647608, DOI: 10.1111/j.1530-0277.2011.01672.x.Peer-Reviewed Original ResearchConceptsStop-signal taskAlcohol useNeural processesSignal taskSocial drinkingRisk takingYoung adult social drinkersFrequency of drinkingAdult social drinkersRight superior frontal gyrusFunctional magnetic resonanceSelf-reported alcohol useSuperior frontal gyrusBrain imaging dataSuperior frontal cortexDangerous alcohol consumptionCognitive factorsNeural correlatesFMRI studyFrontal gyrusSocial drinkersHigh-level drinkingCorresponding effect sizesNumber of drinksNondependent drinkers
2007
Greater activation of the “default” brain regions predicts stop signal errors
Li CS, Yan P, Bergquist KL, Sinha R. Greater activation of the “default” brain regions predicts stop signal errors. NeuroImage 2007, 38: 640-648. PMID: 17884586, PMCID: PMC2097963, DOI: 10.1016/j.neuroimage.2007.07.021.Peer-Reviewed Original ResearchConceptsSignal taskBehavioral adjustmentBrain regionsPost-error behavioral adjustmentCingulate cortexMidline brain regionsStop-signal taskPerigenual anterior cingulate cortexSignal detection theoryPosterior cingulate cortexAnterior cingulate cortexCortical brain regionsCognitive tasksStop successElicit errorsError processingNeural processesStop errorFMRI studyMental effortGreater activationPerformance errorsDetection theoryBilateral precuneusTask