2021
Midcingulate Cortical Activations Interrelate Chronic Craving and Physiological Responses to Negative Emotions in Cocaine Addiction
Zhornitsky S, Le TM, Wang W, Dhingra I, Chen Y, Li CR, Zhang S. Midcingulate Cortical Activations Interrelate Chronic Craving and Physiological Responses to Negative Emotions in Cocaine Addiction. Biological Psychiatry Global Open Science 2021, 1: 37-47. PMID: 35664438, PMCID: PMC9164547, DOI: 10.1016/j.bpsgos.2021.03.003.Peer-Reviewed Original ResearchCD subjectsCocaine cravingMidcingulate cortexControl subjectsSkin conductance responsesBrain activationHealthy control subjectsCocaine Craving QuestionnaireCocaine-dependent subjectsInferior parietal gyrusRegional brain activationChronic cocaineParietal gyrusMotor circuitsPhysiological responsesCocaine addictionDrug cravingCravingNeutral images
2006
Alexithymia and stress-induced brain activation in cocaine-dependent men and women.
Li CS, Sinha R. Alexithymia and stress-induced brain activation in cocaine-dependent men and women. Journal Of Psychiatry And Neuroscience 2006, 31: 115-21. PMID: 16575427, PMCID: PMC1413961.Peer-Reviewed Original ResearchConceptsToronto Alexithymia ScaleFrontal cortexTAS scoresScript-guided imageryAbstinent cocaine-dependent subjectsBilateral temporal cortexFunctional magnetic resonanceStress-induced brain activationProcessing of stressMiddle frontal cortexCocaine-dependent individualsRight frontal cortexCocaine-dependent menCocaine-dependent patientsNeutral imageryNeural processingBrain activationMale cocaine usersStressful situationsCocaine-dependent subjectsRight amygdalaAlexithymic featuresAlexithymia ScaleTemporal cortexSubcortical activation
2005
Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals
Li CS, Milivojevic V, Constable RT, Sinha R. Recent cannabis abuse decreased stress-induced BOLD signals in the frontal and cingulate cortices of cocaine dependent individuals. Psychiatry Research 2005, 140: 271-280. PMID: 16290108, DOI: 10.1016/j.pscychresns.2005.09.002.Peer-Reviewed Original ResearchConceptsPerigenual anterior cingulateAbstinent cocaine-dependent subjectsCocaine-dependent subjectsCannabis abuseCannabis abusersCocaine-dependent individualsAnterior cingulateEmotional stressBOLD signalUrine drug screeningSame statistical thresholdDrug use historyFrontal cortical areasHeavy cannabis useLevel-dependent contrastPrevious neuroimaging studiesFunctional magnetic resonanceFrontal cortexCortical areasAlcohol consumptionCortical activationEmotional stress taskUse of marijuanaBrain regionsDecreased activationSex differences in brain activation during stress imagery in abstinent cocaine users: A functional magnetic resonance imaging study
Li CS, Kosten TR, Sinha R. Sex differences in brain activation during stress imagery in abstinent cocaine users: A functional magnetic resonance imaging study. Biological Psychiatry 2005, 57: 487-494. PMID: 15737663, DOI: 10.1016/j.biopsych.2004.11.048.Peer-Reviewed Original ResearchConceptsAbstinent cocaine usersStress imageryBrain activationAnterior cingulateCingulate cortexFunctional magnetic resonance imaging sessionFunctional magnetic resonance imaging studyMagnetic resonance imaging sessionScript-guided imageryInferior frontal cortexStress-induced cocaineCocaine usersPosterior cingulate cortexRight posterior cingulate cortexSex differencesMagnetic resonance imaging studyImagery vividnessResonance imaging studyFrontolimbic activityImagery periodMore activationDrug seekingFunctional neuroimagingCoping strategiesCocaine-dependent subjects