2013
Error processing and gender-shared and -specific neural predictors of relapse in cocaine dependence
Luo X, Zhang S, Hu S, Bednarski SR, Erdman E, Farr OM, Hong KI, Sinha R, Mazure CM, Li CS. Error processing and gender-shared and -specific neural predictors of relapse in cocaine dependence. Brain 2013, 136: 1231-1244. PMID: 23485852, PMCID: PMC3613717, DOI: 10.1093/brain/awt040.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexFunctional magnetic resonance imagingCognitive controlError-related activationError processingCocaine-dependent individualsAnterior cingulate cortexSignal taskCingulate cortexCocaine dependenceFunctional magnetic resonance imaging (fMRI) dataStop-signal taskTreatment-seeking individualsCross-sectional findingsModerate-sized cohortsBrain activationBehavioral treatmentNeural predictorsDrug useMagnetic resonance imaging dataStatistical Parametric Mapping 8Regional activationPsychosocial factorsSuccess trialsMagnetic resonance imaging
2007
Imaging stress‐ and cue‐induced drug and alcohol craving: association with relapse and clinical implications
SINHA R, LI C. Imaging stress‐ and cue‐induced drug and alcohol craving: association with relapse and clinical implications. Drug And Alcohol Review 2007, 26: 25-31. PMID: 17364833, DOI: 10.1080/09595230601036960.Peer-Reviewed Original ResearchConceptsRelapse outcomesDrug-related cuesPosterior insula regionsCue-induced cravingDrug cue exposureCue-induced drugBrain imaging studiesDrug cuesNeural correlatesCorticostriatal-limbic circuitryCue exposureInsula regionsBrain correlatesRelapse propensityMedial prefrontalBehavioral treatmentAddictive disordersAlcohol cravingPosterior cingulateNeural activityBrain regionsArousal responseLimbic circuitryNeural circuitsCraving