2022
Emotion Processing Dysfunction in Alzheimer’s Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology
Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR. Emotion Processing Dysfunction in Alzheimer’s Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology. American Journal Of Alzheimer's Disease & Other Dementias® 2022, 37: 15333175221082834. PMID: 35357236, PMCID: PMC9212074, DOI: 10.1177/15333175221082834.Peer-Reviewed Original ResearchConceptsEmotional processing deficitsProcessing dysfunctionProcessing deficitsMultiple behavioral paradigmsEmotional memoryEmotional stimuliPositive emotionsAltered emotionsNegative emotionsNeural correlatesEmotional processing dysfunctionAmygdala reactivityBehavioral findingsEmotional disordersCognitive deficitsBehavioral paradigmsProminent deficitsEmotionsAlzheimer's diseaseBehavioral studiesLongitudinal studyNoradrenergic signalingDeficitsCircuit dysfunctionMemory
2017
Proactive Control: Neural Oscillatory Correlates of Conflict Anticipation and Response Slowing
Chang A, Ide JS, Li HH, Chen CC, Li CR. Proactive Control: Neural Oscillatory Correlates of Conflict Anticipation and Response Slowing. ENeuro 2017, 4: eneuro.0061-17.2017. PMID: 28560315, PMCID: PMC5446487, DOI: 10.1523/eneuro.0061-17.2017.Peer-Reviewed Original ResearchConceptsStop-signal taskProactive controlConflict anticipationReaction timeTrial behavioral adjustmentsPrevious functional MRI studiesNeural oscillatory correlatesFunctional MRI studyDelta-theta bandLower theta bandDifferent behavioral paradigmsOscillatory correlatesNeural processesLow beta bandResponse slowingBehavioral adjustmentBehavioral paradigmsFunctional MRITime-frequency activityBehavioral strategiesElectrophysiological studiesElectrophysiological substrateMRI studiesBrain regionsRT clusters
2015
Anticipating conflict: Neural correlates of a Bayesian belief and its motor consequence
Hu S, Ide JS, Zhang S, Li CS. Anticipating conflict: Neural correlates of a Bayesian belief and its motor consequence. NeuroImage 2015, 119: 286-295. PMID: 26095091, PMCID: PMC4564311, DOI: 10.1016/j.neuroimage.2015.06.032.Peer-Reviewed Original ResearchConceptsProactive controlMedial prefrontal cortexNeural correlatesPrefrontal cortexPre-supplementary motor areaTrial reaction timeStop-signal taskBilateral anterior insulaProlonged response timeReaction timeMotor consequencesCognitive controlConflict anticipationRT slowingSignal taskAnterior insulaTarget onsetLarge fMRI data setsPrediction errorBehavioral paradigmsBehavioral consequencesGranger causality analysisFMRI data setsBayesian beliefFMRI signalsResponse Inhibition
Li C. Response Inhibition. 2015, 303-317. DOI: 10.1016/b978-0-12-397025-1.00248-7.Peer-Reviewed Original ResearchResponse inhibitionRight inferior frontal cortexStimulus-driven processesMotor response inhibitionInferior frontal cortexPresupplementary motor areaFunctional brain imagingIndividual brain regionsPsychological constructsNeural substratesComponent processesBehavioral paradigmsReactive controlMotor areaBrain regionsFrontal cortexBrain imagingConceptual frameworkCortexConstructsParadigmDistinctionMonkeys
2008
Neural Correlates of Speeded as Compared with Delayed Responses in a Stop Signal Task: An Indirect Analog of Risk Taking and Association with an Anxiety Trait
Li CS, Chao H, Lee TW. Neural Correlates of Speeded as Compared with Delayed Responses in a Stop Signal Task: An Indirect Analog of Risk Taking and Association with an Anxiety Trait. Cerebral Cortex 2008, 19: 839-848. PMID: 18678764, PMCID: PMC2722793, DOI: 10.1093/cercor/bhn132.Peer-Reviewed Original ResearchConceptsStop-signal taskSignal taskReaction timeTrial reaction timeStop-signal performanceFunctional magnetic resonanceMiddle frontal gyrusAdvantage of variabilityBilateral visual cortexPosterior cingulate cortexCognitive controlNeural correlatesNeural processesAmygdala activityTrait anxietyFrontal gyrusAnxiety traitsBehavioral paradigmsIndirect analogueCingulate cortexNeural analogRisk takingVisual cortexStop signalCurrent study