1988
Beagle puppy model of perinatal asphyxia: Alterations in cerebral blood flow and metabolism
Ment L, Stewart W, Gore J, Duncan C. Beagle puppy model of perinatal asphyxia: Alterations in cerebral blood flow and metabolism. Pediatric Neurology 1988, 4: 98-104. PMID: 3149477, DOI: 10.1016/0887-8994(88)90048-3.Peer-Reviewed Original ResearchConceptsCerebral blood flowBeagle puppy modelPerinatal asphyxiaPuppy modelBlood flowControl of CBFUncoupling of CBFATP/Pi ratioBaseline 1 hourRadioactive microsphere determinationsPCr/PiWhite matter regionsDays of ageAsphyxial episodesAsphyxial insultNeurodevelopmental handicapArterial pressureClinical sequelaeElectrocerebral silenceMicrosphere determinationBrainstem structuresCBF dataBaseline valuesPathologic conditionsAsphyxia
1985
Beagle puppy model of perinatal cerebral infarction. Acute changes in regional cerebral prostaglandins during hemorrhagic hypotension.
Ment L, Stewart W, Duncan C, Cole J, Pitt B. Beagle puppy model of perinatal cerebral infarction. Acute changes in regional cerebral prostaglandins during hemorrhagic hypotension. Journal Of Neurosurgery 1985, 63: 899-904. PMID: 4056903, DOI: 10.3171/jns.1985.63.6.0899.Peer-Reviewed Original ResearchConceptsPerinatal cerebral infarctionPeriventricular white matterNewborn beagle pupsHemorrhagic hypotensionWhite matterCerebral infarctionNeuropathological changesThromboxane B2Beagle pupsMean arterial blood pressureSlow venous hemorrhagePeriventricular white matter regionsArterial blood pressureProstaglandin E2 levelsEffects of hypotensionCerebral blood flowProstaglandin determinationsBeagle puppy modelStable breakdown productWhite matter regionsCerebral prostaglandinsBlood pressureIntensive carePuppy modelPGF1 alphaBeagle puppy model of perinatal cerebral infarction. Acute changes in cerebral blood flow and metabolism during hemorrhagic hypotension.
Ment L, Stewart W, Duncan C, Pitt B, Rescigno A, Cole J. Beagle puppy model of perinatal cerebral infarction. Acute changes in cerebral blood flow and metabolism during hemorrhagic hypotension. Journal Of Neurosurgery 1985, 63: 441-7. PMID: 3839525, DOI: 10.3171/jns.1985.63.3.0441.Peer-Reviewed Original ResearchConceptsLocal cerebral glucose utilizationCerebral blood flowRegional cerebral blood flowHypotensive insultCerebral infarctionHemorrhagic hypotensionBlood flowUncoupling of CBFMean arterial blood pressureNeonatal cerebral infarctionParieto-occipital white matterPerinatal cerebral infarctionSerum prostaglandin levelsSlow venous hemorrhagePeriventricular white matter regionsAutoradiographic determinationArterial blood pressureCerebral glucose utilizationProstaglandin E2 levelsEffects of hypotensionBeagle puppy modelNewborn beagle pupsGray matter structuresStable breakdown productWhite matter regions