Oxytocin enhances brain function in children with autism
Gordon I, Vander Wyk B, Bennett RH, Cordeaux C, Lucas MV, Eilbott JA, Zagoory-Sharon O, Leckman JF, Feldman R, Pelphrey KA. Oxytocin enhances brain function in children with autism. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 20953-20958. PMID: 24297883, PMCID: PMC3876263, DOI: 10.1073/pnas.1312857110.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSuperior temporal sulcusTemporal sulcusOrbitofrontal cortexLeft superior temporal sulcusMiddle frontal gyrusMedial prefrontal cortexRight orbitofrontal cortexSocial attunementSocial judgmentsMeaningful stimuliFrontal gyrusSpectrum disorderBrain activityPrefrontal cortexRight amygdalaSocial functioningFunctional MRIPremotor cortexHedonic evaluationBrain functionJudgmentsCortexChildrenOxytocinSocial, reward, and attention brain networks are involved when online bids for joint attention are met with congruent versus incongruent responses
Gordon I, Eilbott JA, Feldman R, Pelphrey KA, Vander Wyk B. Social, reward, and attention brain networks are involved when online bids for joint attention are met with congruent versus incongruent responses. Social Neuroscience 2013, 8: 544-554. PMID: 24044427, DOI: 10.1080/17470919.2013.832374.Peer-Reviewed Original ResearchConceptsJoint attentionTemporoparietal junctionIncongruent responsesFMRI paradigmFunctional magnetic resonance imaging (fMRI) researchDorsal anterior cingulate cortexNaturalistic fMRI paradigmsHuman social functioningImpact of congruencySocial responsesRight temporoparietal junctionEye gaze patternsRight fusiform gyrusPosterior parietal cortexMagnetic resonance imaging researchAnterior cingulate cortexSocial neuroscienceIncongruent trialsAttention circuitsFusiform gyrusCongruent responsesNeural activationBrain networksRight amygdalaSocial functioning