2020
Diagnostic Reliability and Validity of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA) Chinese Version
Yang BZ, Wang LJ, Huang MC, Wang SC, Tsai MC, Huang YC, Nuñez YZ, Ng MH, Kranzler HR, Gelernter J, Chen CK. Diagnostic Reliability and Validity of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA) Chinese Version. Complex Psychiatry 2020, 6: 62-67. PMID: 34882761, PMCID: PMC7923924, DOI: 10.1159/000511606.Peer-Reviewed Original ResearchSD diagnosisSemi-Structured AssessmentTest-retest reliabilityDependence diagnosisDrug dependenceΚ statisticDiagnostic reliabilityStructured Clinical InterviewCohen κ statisticChance-corrected agreementClinician versionSubstance dependence diagnosesNicotine dependencePsychiatric disordersClinical InterviewAlcohol dependenceDSM-IVDiagnosisSubstance useChinese versionOpioidsValid instrumentConcurrent validityKetamineMethamphetamine
2013
Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking
Stephens SH, Hartz SM, Hoft NR, Saccone NL, Corley RC, Hewitt JK, Hopfer CJ, Breslau N, Coon H, Chen X, Ducci F, Dueker N, Franceschini N, Frank J, Han Y, Hansel NN, Jiang C, Korhonen T, Lind PA, Liu J, Lyytikäinen L, Michel M, Shaffer JR, Short SE, Sun J, Teumer A, Thompson JR, Vogelzangs N, Vink JM, Wenzlaff A, Wheeler W, Yang B, Aggen SH, Balmforth AJ, Baumeister SE, Beaty TH, Benjamin DJ, Bergen AW, Broms U, Cesarini D, Chatterjee N, Chen J, Cheng Y, Cichon S, Couper D, Cucca F, Dick D, Foroud T, Furberg H, Giegling I, Gillespie NA, Gu F, Hall AS, Hällfors J, Han S, Hartmann AM, Heikkilä K, Hickie IB, Hottenga JJ, Jousilahti P, Kaakinen M, Kähönen M, Koellinger PD, Kittner S, Konte B, Landi M, Laatikainen T, Leppert M, Levy SM, Mathias RA, McNeil DW, Medland SE, Montgomery GW, Murray T, Nauck M, North KE, Paré PD, Pergadia M, Ruczinski I, Salomaa V, Viikari J, Willemsen G, Barnes KC, Boerwinkle E, Boomsma DI, Caporaso N, Edenberg HJ, Francks C, Gelernter J, Grabe HJ, Hops H, Jarvelin M, Johannesson M, Kendler KS, Lehtimäki T, Magnusson PK, Marazita ML, Marchini J, Mitchell BD, Nöthen MM, Penninx BW, Raitakari O, Rietschel M, Rujescu D, Samani NJ, Schwartz AG, Shete S, Spitz M, Swan GE, Völzke H, Veijola J, Wei Q, Amos C, Cannon DS, Grucza R, Hatsukami D, Heath A, Johnson EO, Kaprio J, Madden P, Martin NG, Stevens VL, Weiss RB, Kraft P, Bierut LJ, Ehringer MA. Distinct Loci in the CHRNA5/CHRNA3/CHRNB4 Gene Cluster Are Associated With Onset of Regular Smoking. Genetic Epidemiology 2013, 37: 846-859. PMID: 24186853, PMCID: PMC3947535, DOI: 10.1002/gepi.21760.Peer-Reviewed Original ResearchConceptsGene clusterAssociation signalsEarly smoking behaviourSmoking behaviorCHRNA5/A3/B4 gene clusterNicotinic acetylcholine receptor genesRobust association signalsNeuronal nicotinic acetylcholine receptor geneAcetylcholine receptor genesNicotine dependenceCHRNB4 gene clusterSignificant associationB4 gene clusterDistinct lociLung cancer riskRegular tobacco useAssociation resultsNicotine dependence phenotypesDependence phenotypesReceptor geneCotinine levelsRs1948PhenotypeRegular smokingProtective effect
2010
Meta-Analysis of 15 Genome-Wide Linkage Scans of Smoking Behavior
Han S, Gelernter J, Luo X, Yang BZ. Meta-Analysis of 15 Genome-Wide Linkage Scans of Smoking Behavior. Biological Psychiatry 2010, 67: 12-19. PMID: 19819424, PMCID: PMC2975396, DOI: 10.1016/j.biopsych.2009.08.028.Peer-Reviewed Original ResearchConceptsSmoking behaviorGenome-wide suggestive linkageGenome-wide linkage scanSubgroup analysisGenome scan resultsScan resultsLinkage scanSuggestive linkageGenome-wide significant linkageFagerstrom TestCandidate gene identificationNicotine dependenceRe-sequencing studiesMeta-AnalysisSecondary analysis