2021
Immune Checkpoint Inhibitor–associated Diarrhea and Colitis: A Systematic Review and Meta-analysis of Observational Studies
Tran AN, Wang M, Hundt M, Chugh R, Ohm J, Grimshaw A, Ciarleglio M, Hung KW, Proctor DD, Price CC, Laine L, Al-Bawardy B. Immune Checkpoint Inhibitor–associated Diarrhea and Colitis: A Systematic Review and Meta-analysis of Observational Studies. Journal Of Immunotherapy 2021, 44: 325-334. PMID: 34380976, DOI: 10.1097/cji.0000000000000383.Peer-Reviewed Original ResearchConceptsImmune checkpoint inhibitorsDiarrhea/colitisICI therapyCheckpoint inhibitorsObservational studyAnti-programmed cell death-1/Outcomes of ICISystematic reviewCell death-1/Permanent ICI discontinuationReal-world incidenceRemission of diarrheaRecurrence of symptomsDeath-1/Treatment of diarrheaRandom-effects modelICI discontinuationAdvanced malignanciesAppropriate patientsPrimary outcomeOverall incidenceAntigen-4Early treatmentColitisHigh risk
2015
Retained Capsule Endoscopy in a Large Tertiary Care Academic Practice and Radiologic Predictors of Retention
Al-Bawardy B, Locke G, Huprich JE, Fletcher JG, Fidler JL, Barlow JM, Becker B, Rajan E, Loftus EV, Bruining DH, Hansel SL. Retained Capsule Endoscopy in a Large Tertiary Care Academic Practice and Radiologic Predictors of Retention. Inflammatory Bowel Diseases 2015, 21: 2158-2164. PMID: 26284295, DOI: 10.1097/mib.0000000000000482.Peer-Reviewed Original ResearchConceptsCapsule retentionCE retentionPartial obstructionCross-sectional imaging findingsHigh-risk featuresObscure gastrointestinal bleedingPresence of stricturesTertiary care populationComputed tomography scanComputed tomography reportsTreatment of inflammationCapsule endoscopy examinationSmall bowel anastomosisDetails of managementCE indicationsGastrointestinal bleedingObstructive symptomsRadiologic predictorsPatient demographicsCommon indicationGastrointestinal radiologistsRetrospective reviewClinical outcomesHeterogenous cohortImaging findings