2022
The relationship between cannabis use and taurine: A MRS and metabolomics study
Newman S, Martin A, Raymond D, Cheng H, Wilson L, Barnes S, O’Donnell B. The relationship between cannabis use and taurine: A MRS and metabolomics study. PLOS ONE 2022, 17: e0269280. PMID: 35653401, PMCID: PMC9162360, DOI: 10.1371/journal.pone.0269280.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesicsCannabinoid Receptor AgonistsCannabisGlutamic AcidHallucinogensHumansMagnetic Resonance SpectroscopyMetabolomicsTaurineConceptsTaurine levelsCB useBody compositionLow-BMI individualsDorsal anterior cingulateMagnetic resonance spectroscopyNon-user groupNeuroprotective effectsBMI individualsNeurotoxic effectsMRS studiesUrine analysisAnterior cingulateCannabis useSimilar findingsUrine samplesTaurineEssential amino acidsMetabolomic analysisMetabolomics studiesGlutamateCurrent studyGroupBMILevels
2019
An investigation of the relationship between glutamate and resting state connectivity in chronic cannabis users
Newman SD, Cheng H, Kim DJ, Schnakenberg-Martin A, Dydak U, Dharmadhikari S, Hetrick W, O’Donnell B. An investigation of the relationship between glutamate and resting state connectivity in chronic cannabis users. Brain Imaging And Behavior 2019, 14: 2062-2071. PMID: 31302844, PMCID: PMC6955389, DOI: 10.1007/s11682-019-00165-w.Peer-Reviewed Original ResearchMeSH KeywordsCannabisFemaleGlutamic AcidGyrus CinguliHumansMagnetic Resonance SpectroscopyMaleMarijuana SmokingRestYoung AdultConceptsNucleus accumbensGlu levelsState connectivityMultimodal MRI studyState functional connectivityRight nucleus accumbensCB useChronic cannabis usersNAc connectivityHealthy controlsGlutamatergic signalingMRI studiesAnimal studiesCurrent preliminary studyLarger sample sizeMagnetic resonance spectroscopyFunctional connectivityHeavy cannabisCannabis usersCannabisReward networkCB usersLinear regression modelsRSFCEffect size