2024
Trauma exposure among young children in rural Pakistan: Associations with gender, mental health, and cognitive skills
Frost A, Collins A, Chung E, Escobar Carias M, Hagaman A, Gupta S, Bibi A, Sikander S, Maselko J. Trauma exposure among young children in rural Pakistan: Associations with gender, mental health, and cognitive skills. BMC Psychology 2024, 12: 454. PMID: 39183356, PMCID: PMC11346172, DOI: 10.1186/s40359-024-01944-x.Peer-Reviewed Original ResearchConceptsChild mental healthMental healthLow-resource settingsAssociated with increased mental health difficultiesRural PakistanMental health difficultiesTrauma exposureMental health problemsStrength of associationSample of mother-child dyadsIncreased anxiety scoresChildren's lifetime exposureTrauma-informed interventionsMother-child dyadsCognitive healthAssociated with genderHealth difficultiesBackgroundThe burdenAnxiety scoresHealth problemsHealthLifetime exposureExperience traumaChildren's cognitive skillsCognitive skillsChildhood parental bonding and depression in adulthood: A study of mothers in rural Pakistan
Frost A, Hagaman A, Bibi A, Bhalotra S, Chung E, Haight S, Sikander S, Maselko J. Childhood parental bonding and depression in adulthood: A study of mothers in rural Pakistan. Journal Of Affective Disorders 2024, 356: 715-721. PMID: 38663557, PMCID: PMC11103589, DOI: 10.1016/j.jad.2024.04.090.Peer-Reviewed Original ResearchConceptsParental Bonding InstrumentStructured Clinical Interview for DSM DisordersRisk of depressionPsychological controlParenting behaviorsMental healthAssociated with decreased risk of depressionParent-child relationship qualityMeasures of parental controlAssociated with increased risk of depressionDepression in adulthoodRural PakistanMental health of childrenBehavioral controlRetrospective self-reportsMothers' parenting behaviorImpact of parenting behaviorsChild mental healthChildhood parental bondingAssociated with decreased riskHealth of childrenCross-sectional studyAssociated with increased riskDSM disordersAdulthood depression
2022
Stressful life events, intimate partner violence, and perceived stress in the postpartum period: longitudinal findings in rural Pakistan
Haight SC, Gallis JA, Chung EO, Baranov V, Bibi A, Frost A, Hagaman A, Sikander S, Maselko J, Bates LM. Stressful life events, intimate partner violence, and perceived stress in the postpartum period: longitudinal findings in rural Pakistan. Social Psychiatry And Psychiatric Epidemiology 2022, 57: 2193-2205. PMID: 36050505, PMCID: PMC10084399, DOI: 10.1007/s00127-022-02354-3.Peer-Reviewed Original ResearchNon-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan.
Frost A, Hagaman A, Baranov V, Chung EO, Bhalotra S, Sikander S, Maselko J. Non-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan. Development And Psychopathology 2022, 35: 2086-2095. PMID: 35959681, PMCID: PMC9922341, DOI: 10.1017/s0954579422000773.Peer-Reviewed Original ResearchConceptsHPA axis activityMental health difficultiesAxis activityHealth difficultiesEarly childhoodHypothalamic pituitary adrenal axis activityPituitary-adrenal axis activitySDQ scoresAdrenal axis activityNon-linear associationLongitudinal cohortDepression trialsQuadratic associationHair cortisolDehydroepiandosteroneRural PakistanMental healthCortisolEarly adversitySignificant quadratic associationDifficulties QuestionnaireLow-resource contextsChildhoodChildrenAssociationAdverse childhood experiences and implications of perceived stress, anxiety and cortisol among women in Pakistan: a cross-sectional study
Ikram N, Frost A, LeMasters K, Hagaman A, Baranov V, Gallis J, Sikander S, Scherer E, Maselko J. Adverse childhood experiences and implications of perceived stress, anxiety and cortisol among women in Pakistan: a cross-sectional study. BMJ Open 2022, 12: e052280. PMID: 35428618, PMCID: PMC9014037, DOI: 10.1136/bmjopen-2021-052280.Peer-Reviewed Original ResearchMother-in-law childcare and perinatal depression in rural Pakistan
Chung E, Hagaman A, Bibi A, Frost A, Haight S, Sikander S, Maselko J. Mother-in-law childcare and perinatal depression in rural Pakistan. Women's Health 2022, 18: 17455057221141288. PMID: 36468464, PMCID: PMC9726850, DOI: 10.1177/17455057221141288.Peer-Reviewed Original ResearchConceptsPerinatal depressionMaternal mental healthMonths postpartumMental healthImmediate postpartum periodFirst year postpartumStructured Clinical InterviewCross-sectional associationsHigh motherMental Disorders-IVYear postpartumLife Events ChecklistPostpartum periodMajor depressionPerinatal periodMaternal depressionLow prevalenceBirth cohortClinical InterviewLow motherPostpartumRural PakistanStatistical ManualDepressionMothers
2021
Adverse childhood experiences and depression among women in rural Pakistan
LeMasters K, Bates LM, Chung EO, Gallis JA, Hagaman A, Scherer E, Sikander S, Staley BS, Zalla LC, Zivich PN, Maselko J. Adverse childhood experiences and depression among women in rural Pakistan. BMC Public Health 2021, 21: 400. PMID: 33632175, PMCID: PMC7905421, DOI: 10.1186/s12889-021-10409-4.Peer-Reviewed Original ResearchConceptsMajor depressive episodeSymptom severityPerinatal mental health interventionsWomen's depressionBackgroundAdverse childhood experiencesDepressive symptom severityMajority of womenACE-International QuestionnaireCurrent mental healthMental health interventionsAdverse childhood experiencesChildhood experiencesCohort studyDepressive episodeMonths postpartumPerinatal periodElevated riskPronounced elevationHealth interventionsMore ACEsRural PakistanMental healthFamily distressCommon pathwayDepression
2020
Effectiveness of a peer-delivered, psychosocial intervention on maternal depression and child development at 3 years postnatal: a cluster randomised trial in Pakistan
Maselko J, Sikander S, Turner EL, Bates LM, Ahmad I, Atif N, Baranov V, Bhalotra S, Bibi A, Bibi T, Bilal S, Biroli P, Chung E, Gallis JA, Hagaman A, Jamil A, LeMasters K, O'Donnell K, Scherer E, Sharif M, Waqas A, Zaidi A, Zulfiqar S, Rahman A. Effectiveness of a peer-delivered, psychosocial intervention on maternal depression and child development at 3 years postnatal: a cluster randomised trial in Pakistan. The Lancet Psychiatry 2020, 7: 775-787. PMID: 32828167, PMCID: PMC8015797, DOI: 10.1016/s2215-0366(20)30258-3.Peer-Reviewed Original ResearchConceptsMaternal depressionPsychosocial interventionsUsual careLong-term maternal outcomesMaternal depression symptomsAllocation statusScalable psychosocial interventionsMaternal outcomesRandomisation sequencePrimary outcomePregnant womenExcess riskDepression exposureRecurring courseSevere symptomsTrial participantsOffspring outcomesDepression symptomsDepressionVillage clustersInterventionTrialsOutcomesSymptomsPrincipal investigatorThe contribution of grandmother involvement to child growth and development: an observational study in rural Pakistan
Chung EO, Hagaman A, LeMasters K, Andrabi N, Baranov V, Bates LM, Gallis JA, O'Donnell K, Rahman A, Sikander S, Turner EL, Maselko J. The contribution of grandmother involvement to child growth and development: an observational study in rural Pakistan. BMJ Global Health 2020, 5: e002181. PMID: 32784209, PMCID: PMC7418670, DOI: 10.1136/bmjgh-2019-002181.Peer-Reviewed Original ResearchAssociation of maternal depression and home adversities with infant hypothalamic-pituitary-adrenal (HPA) axis biomarkers in rural Pakistan
Hagaman AK, Baranov V, Chung E, LeMasters K, Andrabi N, Bates LM, Rahman A, Sikander S, Turner E, Maselko J. Association of maternal depression and home adversities with infant hypothalamic-pituitary-adrenal (HPA) axis biomarkers in rural Pakistan. Journal Of Affective Disorders 2020, 276: 592-599. PMID: 32871690, PMCID: PMC7792907, DOI: 10.1016/j.jad.2020.07.053.Peer-Reviewed Original ResearchConceptsHPA axis activityMaternal depressionSocio-economic statusYear postpartumDHEAS levelsAxis activityIntimate partner violenceInfant stress response systemsSignificant associationLow DHEAS levelsHPA axis dysregulationHPA axis hormonesOne-year-old infantsYears of ageConsistent significant associationsChildren's HPA-axis activityHigher socio-economic statusSignificant positive associationAxis dysregulationAxis hormonesAdrenal axisStress-related diseasesDHEA activityInfant cortisolDepression severityMaternal depression in rural Pakistan: the protective associations with cultural postpartum practices
LeMasters K, Andrabi N, Zalla L, Hagaman A, Chung EO, Gallis JA, Turner EL, Bhalotra S, Sikander S, Maselko J. Maternal depression in rural Pakistan: the protective associations with cultural postpartum practices. BMC Public Health 2020, 20: 68. PMID: 31941468, PMCID: PMC6964000, DOI: 10.1186/s12889-020-8176-0.Peer-Reviewed Original ResearchConceptsMajor depressive episodePostpartum depressionTraditional postpartum practicesMonths postpartumSymptom severityLower symptom severityPostpartum practicesMaternal mental healthPatient Health QuestionnaireSocial supportStructured Clinical InterviewDepression symptom severityResultsEighty-nine percentCohort studyThird trimesterDepressive episodePrenatal depressionDepression statusHealth QuestionnaireProtective associationMaternal depressionLower oddsAdjusted modelClinical InterviewDays postpartum
2019
Psychosocial determinants of sustained maternal functional impairment: Longitudinal findings from a pregnancy-birth cohort study in rural Pakistan
Hagaman A, Gallis JA, Bhalotra S, Baranov V, Turner EL, Sikander S, Maselko J. Psychosocial determinants of sustained maternal functional impairment: Longitudinal findings from a pregnancy-birth cohort study in rural Pakistan. PLOS ONE 2019, 14: e0225163. PMID: 31743374, PMCID: PMC6863521, DOI: 10.1371/journal.pone.0225163.Peer-Reviewed Original ResearchConceptsPoor functioningFunctional impairmentPsychosocial characteristicsPerinatal mental healthFunctional trajectoriesPublic health implicationsImportant protective roleHigh functioning groupGroup-based trajectory modeling approachCohort studyThird trimesterFunction recoveryPerinatal periodAssess predictorsChild CohortProtective rolePsychosocial determinantsOne-yearMental healthImportant markerHealth implicationsTrajectory groupsFunctioning groupPregnancyLongitudinal findingsFather involvement in the first year of life: Associations with maternal mental health and child development outcomes in rural Pakistan
Maselko J, Hagaman AK, Bates LM, Bhalotra S, Biroli P, Gallis JA, O'Donnell K, Sikander S, Turner EL, Rahman A. Father involvement in the first year of life: Associations with maternal mental health and child development outcomes in rural Pakistan. Social Science & Medicine 2019, 237: 112421. PMID: 31398510, PMCID: PMC6708722, DOI: 10.1016/j.socscimed.2019.112421.Peer-Reviewed Original ResearchConceptsMaternal mental healthMonths postpartumMaternal depressionMental healthPerinatal depression interventionChild growthFirst yearDepression interventionsFather involvementProtective associationHigh-income countriesMost mothersBirth cohortChild development outcomesChild developmentPostpartumEffect estimatesProtective patternTime pointsDevelopmental milestonesConfidence intervalsRural settingsLongitudinal dataDepressionIncome countriesCohort Profile: Perinatal depression and child socioemotional development ; the Bachpan cohort study from rural Pakistan
Sikander S, Ahmad I, Bates LM, Gallis J, Hagaman A, O’Donnell K, Turner EL, Zaidi A, Rahman A, Maselko J. Cohort Profile: Perinatal depression and child socioemotional development ; the Bachpan cohort study from rural Pakistan. BMJ Open 2019, 9: e025644. PMID: 31061029, PMCID: PMC6502044, DOI: 10.1136/bmjopen-2018-025644.Peer-Reviewed Original ResearchConceptsSocioemotional developmentDetrimental developmental outcomesChildren's socioemotional developmentMother-child dyadsPerinatal depressionEffect of depressionSocioemotional measuresChild developmentDevelopmental outcomesPsychosocial measuresPoor child developmentPregnancy birth cohortChild's ageSchool environmentCohort studyInflammatory biomarkersChronic courseEligible dyadsPregnant womenRisk factorsBaseline assessmentRepeated measuresDyadsDepressionChildrenThe relationship between responsive caregiving and child outcomes: evidence from direct observations of mother-child dyads in Pakistan
Scherer E, Hagaman A, Chung E, Rahman A, O’Donnell K, Maselko J. The relationship between responsive caregiving and child outcomes: evidence from direct observations of mother-child dyads in Pakistan. BMC Public Health 2019, 19: 252. PMID: 30819173, PMCID: PMC6396475, DOI: 10.1186/s12889-019-6571-1.Peer-Reviewed Original ResearchConceptsChildren's socioemotional developmentResponsive caregivingSocioemotional developmentChild developmentCaregiving behaviorChild outcomesMother-child interaction measuresMaternal depressionChildren's socioemotional outcomesMother-child dyadsChild development outcomesHierarchical linear regressionSocioemotional outcomesChild's signalsChild behaviorHome ObservationHOME scoresPhysical outcomesCaregivingLongitudinal studyLower scoresChild's lifeBook activitiesCross-sectional associationsBaseline sociodemographic factors