2007
The derivatives of the Wnt3a lineage in the central nervous system
Louvi A, Yoshida M, Grove EA. The derivatives of the Wnt3a lineage in the central nervous system. The Journal Of Comparative Neurology 2007, 504: 550-569. PMID: 17701978, DOI: 10.1002/cne.21461.Peer-Reviewed Original ResearchConceptsSpinal cordCervical spinal cordTrigeminal sensory systemRostral spinal cordCentral nervous systemCentral auditory systemDorsal midlineGenetic fate mappingSpecific functional networksAdult brainNervous systemDorsal halfBrain structuresCordLineage cellsAuditory systemMidbrainCell fate specificationVertebrate neural tubeNeural tubeFate mappingFunctional networksTransient gene expressionMidlineFate specification
2005
CCM2 Expression Parallels That of CCM1
Seker A, Pricola KL, Guclu B, Ozturk AK, Louvi A, Gunel M. CCM2 Expression Parallels That of CCM1. Stroke 2005, 37: 518-523. PMID: 16373645, DOI: 10.1161/01.str.0000198835.49387.25.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBlotting, WesternBrainCarrier ProteinsCells, CulturedCentral Nervous SystemCerebral CortexChlorocebus aethiopsCOS CellsEndothelium, VascularHumansImmunohistochemistryIn Situ HybridizationKRIT1 ProteinMiceMicrotubule-Associated ProteinsMuscle, SmoothMutationNeuronsPhenotypeProto-Oncogene ProteinsRNA, MessengerSignal TransductionTime FactorsTwo-Hybrid System TechniquesUmbilical VeinsConceptsCerebral cavernous malformationsProtein expressionExtracerebral tissuesFamilial cerebral cavernous malformationsArterial vascular endotheliumPostnatal mouse brainSmooth muscle cellsVascular wall elementsWestern blot analysisExpression patternsPyramidal neuronsVenous circulationCerebral tissueNeurovascular diseasesCavernous malformationsImmunohistochemical analysisVascular endotheliumMouse brainMRNA expressionMuscle cellsFoot processesEpithelial cellsExpression parallelsDisease phenotypeSpatial expression patternsWNK3 modulates transport of Cl- in and out of cells: Implications for control of cell volume and neuronal excitability
Kahle KT, Rinehart J, de los Heros P, Louvi A, Meade P, Vazquez N, Hebert SC, Gamba G, Gimenez I, Lifton RP. WNK3 modulates transport of Cl- in and out of cells: Implications for control of cell volume and neuronal excitability. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 16783-16788. PMID: 16275911, PMCID: PMC1283843, DOI: 10.1073/pnas.0508307102.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell SizeChloridesIn Situ HybridizationIon TransportMiceNeuronsPhosphorylationProtein Serine-Threonine KinasesConceptsReticular activating systemCl- influxAltered phosphorylationCerebral cortexResponsive neuronsGABA neurotransmissionNeuronal excitabilityK-Cl cotransporterOpposite effectActivating systemCotransporter NKCC1Intracellular ClCl- effluxNKCC1Surface expressionKCC2Cell volumeExcitabilityNeuronsDownstream targetsWNK3Sensitive kinasesXenopus oocytesIntracellular volumeIon cotransporters
2004
Presenilin 1 in migration and morphogenesis in the central nervous system
Louvi A, Sisodia SS, Grove EA. Presenilin 1 in migration and morphogenesis in the central nervous system. Development 2004, 131: 3093-3105. PMID: 15163631, DOI: 10.1242/dev.01191.Peer-Reviewed Original ResearchMeSH KeywordsAmyloid Precursor Protein SecretasesAnimalsAspartic Acid EndopeptidasesBrainBrain StemBromodeoxyuridineCell DifferentiationCell DivisionCell MovementCentral Nervous SystemCerebellumColoring AgentsCyclin-Dependent Kinase 5Cyclin-Dependent KinasesCytoskeletonDopamine AgentsEndopeptidasesGene Expression Regulation, DevelopmentalHomozygoteImmunohistochemistryIn Situ HybridizationLightMembrane ProteinsMiceMutationNeuronsPresenilin-1Time FactorsConceptsCentral nervous systemNervous systemPresenilin 1Premature neuronal differentiationCNS morphogenesisCerebral cortexCortical dysplasiaCortical laminationExternal granule layerPontine nucleiPresenilin-1 functionCerebellar granule cell precursorsFacial branchiomotor nucleusTangential migratory pathwayCaudal midbrainGranule cell precursorsNeuronal cellsBrain developmentNeuronal migrationTangential migrationBranchiomotor nucleiCell precursorsNeuronal differentiationGranule layerMidline fusion