Anti-Aβ1–11 Antibody Binds to Different β-Amyloid Species, Inhibits Fibril Formation, and Disaggregates Preformed Fibrils but Not the Most Toxic Oligomers*
Mamikonyan G, Necula M, Mkrtichyan M, Ghochikyan A, Petrushina I, Movsesyan N, Mina E, Kiyatkin A, Glabe C, Cribbs D, Agadjanyan M. Anti-Aβ1–11 Antibody Binds to Different β-Amyloid Species, Inhibits Fibril Formation, and Disaggregates Preformed Fibrils but Not the Most Toxic Oligomers*. Journal Of Biological Chemistry 2007, 282: 22376-22386. PMID: 17545160, PMCID: PMC2435219, DOI: 10.1074/jbc.m700088200.Peer-Reviewed Original ResearchMeSH KeywordsAmyloidAmyloid beta-PeptidesAnimalsBrainCytokinesEpitopesHippocampusHumansImmune SystemMiceMicroscopy, Electron, TransmissionMolecular ConformationProtein BindingSpleenT-Lymphocytes