2023
Economic Evaluation of Extended-Release Buprenorphine for Persons With Opioid Use Disorder
Flam-Ross J, Marsh E, Weitz M, Savinkina A, Schackman B, Wang J, Madushani R, Morgan J, Barocas J, Walley A, Chrysanthopoulou S, Linas B, Assoumou S. Economic Evaluation of Extended-Release Buprenorphine for Persons With Opioid Use Disorder. JAMA Network Open 2023, 6: e2329583. PMID: 37703018, PMCID: PMC10500382, DOI: 10.1001/jamanetworkopen.2023.29583.Peer-Reviewed Original ResearchMeSH KeywordsAdultBuprenorphineCost-Benefit AnalysisFemaleHumansMaleMiddle AgedOpioid-Related DisordersPatient Acceptance of Health CareUnited StatesConceptsExtended-release buprenorphineIncremental cost-effectiveness ratioMedication treatmentHealth care utilization costsTreatment of OUDOpioid agonist treatmentOpioid use disorderMean lifetime costsCost-effectiveness ratioProbabilistic sensitivity analysesEconomic evaluationCohort studyAgonist treatmentTreatment optionsClinical trialsClosed cohortMAIN OUTCOMEBuprenorphineSimulated cohortUse disordersDrug AdministrationUS FoodPharmaceutical costsQALY willingnessInjectable form
2021
Clinical impact, costs, and cost-effectiveness of hospital-based strategies for addressing the US opioid epidemic: a modelling study
Barocas JA, Savinkina A, Adams J, Jawa R, Weinstein ZM, Samet JH, Linas BP. Clinical impact, costs, and cost-effectiveness of hospital-based strategies for addressing the US opioid epidemic: a modelling study. The Lancet Public Health 2021, 7: e56-e64. PMID: 34861189, PMCID: PMC8756295, DOI: 10.1016/s2468-2667(21)00248-6.Peer-Reviewed Original ResearchConceptsOpioid use disorderAddiction consult serviceHospital-based strategiesUS opioid epidemicOpioid epidemicUse disordersConsult serviceProbabilistic sensitivity analysesClinical impactDrug useIncremental cost-effectiveness ratioInjection-related infectionsInjection drug useMean lifetime costsNational InstituteCost-effectiveness ratioHarm reduction servicesDeterministic sensitivity analysesInpatient prescribingObservational cohortRecurrent infectionsOutpatient treatmentClinical trialsOverdose riskMedications
2020
A clash of epidemics: Impact of the COVID-19 pandemic response on opioid overdose
Linas BP, Savinkina A, Barbosa C, Mueller PP, Cerdá M, Keyes K, Chhatwal J. A clash of epidemics: Impact of the COVID-19 pandemic response on opioid overdose. Journal Of Substance Use And Addiction Treatment 2020, 120: 108158. PMID: 33298298, PMCID: PMC7536128, DOI: 10.1016/j.jsat.2020.108158.Peer-Reviewed Original ResearchMeSH KeywordsComputer SimulationCOVID-19HumansMental HealthOpiate OverdoseOpioid-Related DisordersPatient Acceptance of Health CarePhysical DistancingPublic HealthQuarantineConceptsOpioid use disorderCOVID-19 infectionCoronavirus disease 2019COVID-19Treatment-seeking behaviorPhysical distancingCOVID-19 pandemic responseOpioid epidemicDisease 2019Overdose mortalityUse disordersGreater substance usePhysical distancing interventionsMental healthQuarantine interventionSubstance useDrug supplyPandemic responsePublic healthHealthInterventionEpidemicDirect effectPossible mechanismOpioids