2022
Left Ventricular Remodeling After Anterior-STEMI PCI: Imaging Observations in the Door-to-Unload (DTU) Pilot Trial.
O'Neill WW, Wang DD, Polak S, Moses JW, Josephy N, Koenig G, Kim RJ, Lansky A, Bellumkonda L, Douglas PS, Kapur NK. Left Ventricular Remodeling After Anterior-STEMI PCI: Imaging Observations in the Door-to-Unload (DTU) Pilot Trial. Journal Of Invasive Cardiology 2022, 34: e611-e619. PMID: 35830361, DOI: 10.25270/jic/21.00401.Peer-Reviewed Original ResearchConceptsCardiac magnetic resonanceLV ejection fractionInfarct sizeLeft ventricularLV unloadingEjection fractionPilot trialGroup 2Group 1ST-segment elevation myocardial infarction (STEMI) patientsImproved LV ejection fractionElevation myocardial infarction patientsLV end-diastolic volumeMajor cardiovascular outcomesPercutaneous coronary interventionMyocardial infarction patientsEnd-diastolic volumeEnd-systolic volumeAnterior STEMIEchocardiographic LVEFCardiogenic shockCardiovascular outcomesEchocardiographic parametersImmediate reperfusionCoronary intervention
2021
Outcomes of bailout percutaneous ventricular assist device versus prophylactic strategy in patients undergoing nonemergent percutaneous coronary intervention
O'Neill BP, Grines C, Moses JW, Ohman EM, Lansky A, Popma J, Kapur NK, Schreiber T, Mannino S, O'Neill WW, Medjamia AM, Mahmud E. Outcomes of bailout percutaneous ventricular assist device versus prophylactic strategy in patients undergoing nonemergent percutaneous coronary intervention. Catheterization And Cardiovascular Interventions 2021, 98: e501-e512. PMID: 34051033, DOI: 10.1002/ccd.29758.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHeart-Assist DevicesHumansPercutaneous Coronary InterventionRetrospective StudiesRisk FactorsStroke VolumeTreatment OutcomeVentricular Function, LeftConceptsPercutaneous ventricular assist deviceNonemergent percutaneous coronary interventionPercutaneous coronary interventionHemodynamic collapseVentricular assist deviceCoronary interventionProphylactic supportImpella percutaneous ventricular assist deviceAssist deviceOutcomes of patientsVentricular ejection fractionHospital mortalityHospital outcomesEjection fractionHeart failureMedian baselinePVAD supportProphylactic strategiesFemale genderStudy populationLow prevalencePatientsMain diseaseOutcomesMortality
2013
The prognostic importance of left ventricular function in patients with ST-segment elevation myocardial infarction: the HORIZONS-AMI trial
Ng VG, Lansky AJ, Meller S, Witzenbichler B, Guagliumi G, Peruga JZ, Brodie B, Shah R, Mehran R, Stone GW. The prognostic importance of left ventricular function in patients with ST-segment elevation myocardial infarction: the HORIZONS-AMI trial. European Heart Journal Acute Cardiovascular Care 2013, 3: 67-77. PMID: 24562805, PMCID: PMC3932775, DOI: 10.1177/2048872613507149.Peer-Reviewed Original ResearchMeSH KeywordsAgedAntithrombinsCoronary AngiographyDrug-Eluting StentsElectrocardiographyFemaleFollow-Up StudiesGated Blood-Pool ImagingHirudinsHumansMaleMiddle AgedMyocardial InfarctionPeptide FragmentsPercutaneous Coronary InterventionPrognosisProspective StudiesRecombinant ProteinsTreatment OutcomeVentricular Function, LeftConceptsST-segment elevation myocardial infarctionLeft ventricular ejection fractionPaclitaxel-eluting stentsHORIZONS-AMI trialElevation myocardial infarctionLV dysfunctionLV functionMyocardial infarctionIschaemia-driven target lesion revascularizationMajor adverse cardiovascular eventsNet adverse clinical eventsPrimary percutaneous coronary interventionBaseline LV dysfunctionIndex revascularization procedureAdverse cardiovascular eventsOutcomes of patientsTarget lesion revascularizationHigh-risk patientsSubstantial clinical benefitAdverse clinical eventsNormal LV functionPercutaneous coronary interventionVentricular ejection fractionLeft ventricular functionBare metal stents
2011
The Relationship Between Attenuated Plaque Identified by Intravascular Ultrasound and No-Reflow After Stenting in Acute Myocardial Infarction The HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) Trial
Wu X, Mintz GS, Xu K, Lansky AJ, Witzenbichler B, Guagliumi G, Brodie B, Kellett MA, Dressler O, Parise H, Mehran R, Stone GW, Maehara A. The Relationship Between Attenuated Plaque Identified by Intravascular Ultrasound and No-Reflow After Stenting in Acute Myocardial Infarction The HORIZONS-AMI (Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction) Trial. JACC Cardiovascular Interventions 2011, 4: 495-502. PMID: 21596321, DOI: 10.1016/j.jcin.2010.12.012.Peer-Reviewed Original ResearchMeSH KeywordsAngioplasty, Balloon, CoronaryChi-Square DistributionCoronary AngiographyCoronary Artery DiseaseCoronary CirculationEuropeHumansLogistic ModelsMulticenter Studies as TopicMyocardial InfarctionNo-Reflow PhenomenonPlaque, AtheroscleroticPredictive Value of TestsRandomized Controlled Trials as TopicRetrospective StudiesRisk AssessmentRisk FactorsStentsStroke VolumeTreatment OutcomeUltrasonography, InterventionalUnited StatesVentricular Function, LeftConceptsAcute myocardial infarctionAttenuated plaqueHORIZONS-AMI trialPercutaneous coronary interventionMyocardial infarctionAttenuation scoreIntravascular ultrasoundVentricular ejection fractionGrayscale intravascular ultrasoundAngiographic thrombusFinal ThrombolysisCoronary interventionDistal embolizationEjection fractionMechanical obstructionTransient deteriorationCoronary flowStent implantationNo-ReflowPatientsMultivariate analysisLower baselineStent expansionInfarctionPlaques
2004
Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC trial)
Halkin A, Aymong E, Cox DA, Mehran R, Lansky AJ, Fahy M, Weisz G, Garcia E, Tcheng JE, Grines CL, Stone GW. Relation between late patency of the infarct-related artery, left ventricular function, and clinical outcomes after primary percutaneous intervention for acute myocardial infarction (CADILLAC trial). The American Journal Of Cardiology 2004, 93: 349-353. PMID: 14759389, DOI: 10.1016/j.amjcard.2003.10.019.Peer-Reviewed Original ResearchConceptsInfarct-related arteryPercutaneous coronary interventionAcute myocardial infarctionInfarct arteryCoronary interventionVentricular functionClinical outcomesMyocardial infarctionMyocardial Infarction trial (TIMI) grade 3 flowPrimary percutaneous coronary interventionLeft ventricular ejection fractionDegree of restenosisGrade 3 flowPrimary percutaneous interventionEvent-free survivalVentricular ejection fractionLeft ventricular functionSustained patencyRoutine followEjection fractionIndependent predictorsLate patencyPercutaneous interventionSerial measuresArtery
2001
Clinical outcome following percutaneous coronary interventions in patients with chronic renal failure
Gruberg L, Dangas G, Mehran R, Mintz GS, Kent KM, Pichard AD, Satler LF, Lansky AJ, Stone GW, Leon MB. Clinical outcome following percutaneous coronary interventions in patients with chronic renal failure. Catheterization And Cardiovascular Interventions 2001, 55: 66-72. PMID: 11793497, DOI: 10.1002/ccd.10103.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseChronic renal failurePercutaneous coronary interventionClinical outcomesLate mortalityRenal dysfunctionCoronary interventionRenal failureRenal functionRenal diseaseHigher left ventricular ejection fractionNon-Q-wave myocardial infarctionLeft ventricular ejection fractionAngiographic success rateImpaired renal functionNormal renal functionVentricular ejection fractionHospital mortalityCreatinine clearanceConsecutive patientsDiabetes mellitusEjection fractionIndependent correlatesMyocardial infarctionLarge cohort