2018
New Method for Quantification of the Left Ventricular Function from Low-dose Equilibrium Radionuclide Angiocardiography: Comparisons with Conventional Methods in Patients
Liu Y, Tsatkin V, Fazzone-Chettiar R, Miller E, Sinusas A. New Method for Quantification of the Left Ventricular Function from Low-dose Equilibrium Radionuclide Angiocardiography: Comparisons with Conventional Methods in Patients. 2018, 00: 1-3. DOI: 10.1109/nssmic.2018.8824749.Peer-Reviewed Original ResearchEnd-diastolic volumeEquilibrium radionuclide angiocardiographyLeft ventricular functionGated blood pool SPECTPeak filling rateBlood pool SPECTEjection fractionVentricular functionRadionuclide angiocardiographyLV end-diastolic volumeHigh-dose injectionLow-dose injectionsAnterior oblique viewSingle photon emissionRed blood cellsDose reductionReduced radiation dosePatientsShort-axis slicesBlood cellsRadiation exposureGold standardImaging modalitiesRadiation doseOblique view
2004
Evaluation of myocardial matrix metalloproteinase (MMP) mediated post-MI remodeling with a novel radiolabeled MMP inhibitor
Su H, Spinale F, Dobrucki1 L, Chow C, Sweterlitsch S, Hu X, Bourke B, Cavaliere P, Hua J, Azure M, Edwards D, Sinusas A. Evaluation of myocardial matrix metalloproteinase (MMP) mediated post-MI remodeling with a novel radiolabeled MMP inhibitor. Journal Of Nuclear Cardiology 2004, 11: s20. DOI: 10.1016/j.nuclcard.2004.06.063.Peer-Reviewed Original ResearchMyocardial infarctionPost-MI remodelingPost-myocardial infarctionMMP activationMMP inhibitorsControl groupSitu zymographyMyocardial matrix metalloproteinasesMI regionMin post injectionControl miceMI miceVentricular remodelingPost-MIMI groupMurine modelNew therapiesMatrix metalloproteinaseMMP activityMatrix metalloproteinasesShort-axis slicesMI areaPost injectionMyocardial retentionMice
1996
Quantification of technetium 99m-labeled sestamibi single-photon emission computed tomography based on mean counts improves accuracy for assessment of relative regional myocardial blood flow: Experimental validation in a canine model
Liu Y, Sinusas A, Shi C, Shen M, Dione D, Heller E, Wackers F. Quantification of technetium 99m-labeled sestamibi single-photon emission computed tomography based on mean counts improves accuracy for assessment of relative regional myocardial blood flow: Experimental validation in a canine model. Journal Of Nuclear Cardiology 1996, 3: 312-320. PMID: 8799250, DOI: 10.1016/s1071-3581(96)90091-4.Peer-Reviewed Original ResearchConceptsMyocardial blood flowRelative blood flowRelative myocardial blood flowRegional myocardial blood flowCoronary artery occlusionBlood flowSingle photon emissionArtery occlusionCanine modelShort-axis slicesEx vivoSestamibi single-photon emissionMyocardial countsFlow deficitsMyocardial count densityNormal blood flowMean countsRegional myocardial perfusionCount profilesMIBI uptakeMIBI SPECTSestamibi SPECTMyocardial perfusionCircumferential count profilesRelative regional myocardial blood flow