2023
Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa
Ammar A, Elsamadicy A, Ammar M, Reeves B, Koo A, Falcone G, Hwang D, Petersen N, Kim J, Beekman R, Prust M, Magid-Bernstein J, Acosta J, Herbert R, Sheth K, Matouk C, Gilmore E. Emergent external ventricular drain placement in patients with factor Xa inhibitor-associated intracerebral hemorrhage after reversal with andexanet alfa. Clinical Neurology And Neurosurgery 2023, 226: 107621. PMID: 36791588, DOI: 10.1016/j.clineuro.2023.107621.Peer-Reviewed Original ResearchConceptsAndexanet alfaExtra-axial hemorrhageEVD placementThrombotic eventsNew hemorrhagePrimary safety outcomeExternal ventricular drain placementLarge prospective studiesIntensive care unitIntracerebral hemorrhage patientsVentricular drain placementBolus patientsHospital lengthHospital LOSICU LOSTract hemorrhageRankin scoreSecondary outcomesAdult patientsBolus groupPrimary outcomeCare unitIntracerebral hemorrhageLong administration timeHemorrhage patients
2021
Impact of race on nonroutine discharge, length of stay, and postoperative complications after surgery for spinal metastases.
Hung B, Pennington Z, Hersh AM, Schilling A, Ehresman J, Patel J, Antar A, Porras JL, Elsamadicy AA, Sciubba DM. Impact of race on nonroutine discharge, length of stay, and postoperative complications after surgery for spinal metastases. Journal Of Neurosurgery Spine 2021, 36: 678-685. PMID: 34740176, DOI: 10.3171/2021.7.spine21287.Peer-Reviewed Original ResearchMeSH KeywordsAftercareHumansLength of StayPatient DischargePostoperative ComplicationsProspective StudiesRetrospective StudiesSpinal NeoplasmsConceptsLow preoperative KPS scoreNonroutine dischargePreoperative KPS scoreSpinal metastasesInsurance statusPostoperative complicationsKPS scoreIndependent predictorsFunctional statusPreoperative Karnofsky Performance Scale scoreHigher Charlson comorbidity indexSingle comprehensive cancer centerKarnofsky Performance Scale scoreStepwise multivariable logistic regressionFrankel grade ANonhome discharge destinationCharlson Comorbidity IndexPreoperative clinical characteristicsPrimary tumor typeBaseline functional statusMultivariable logistic regressionMarital statusLength of stayPerformance Scale scoreComprehensive cancer center
2020
Impact of Preoperative Anemia on Outcomes After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis
Elsamadicy AA, Freedman IG, Koo AB, David WB, Havlik J, Kundishora AJ, Hong CS, Sciubba DM, Kahle KT, DiLuna M. Impact of Preoperative Anemia on Outcomes After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. World Neurosurgery 2020, 146: e214-e224. PMID: 33091648, DOI: 10.1016/j.wneu.2020.10.074.Peer-Reviewed Original ResearchConceptsPosterior spinal fusionAdolescent idiopathic scoliosisPreoperative anemiaAnemic cohortHospital stayReadmission ratesIndependent predictorsSpinal fusionIdiopathic scoliosisNational Surgical Quality Improvement Program Pediatric databaseSurgeons National Surgical Quality Improvement Program Pediatric databaseUnplanned reoperation rateLonger hospital stayRetrospective cohort studyThirty-day outcomesLonger operative timeLonger lengthPostoperative complicationsReoperation rateCohort studyDischarge dispositionComplication ratePediatric patientsTransfusion eventsOperative time
2018
Influence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery.
Elsamadicy AA, Kemeny H, Adogwa O, Sankey EW, Goodwin CR, Yarbrough CK, Lad SP, Karikari IO, Gottfried ON. Influence of racial disparities on patient-reported satisfaction and short- and long-term perception of health status after elective lumbar spine surgery. Journal Of Neurosurgery Spine 2018, 29: 40-45. PMID: 29701564, DOI: 10.3171/2017.12.spine171079.Peer-Reviewed Original ResearchMeSH KeywordsBlack or African AmericanDiagnostic Self EvaluationDisability EvaluationElective Surgical ProceduresFemaleHealth StatusHealthcare DisparitiesHumansLumbar VertebraeMaleMiddle AgedPainPatient Reported Outcome MeasuresPatient SatisfactionPrevalenceProspective StudiesRetrospective StudiesSelf ConceptTime FactorsWhite PeopleConceptsElective lumbar spine surgeryPatient-reported outcomesLumbar spine surgerySpine surgeryPatient satisfactionRacial disparitiesPatient demographicsReadmission ratesWhite patientsAA patientsMedical recordsLong-term patient-reported outcomesOverall patient-reported outcomeGreater body mass indexBaseline patient demographicsInferior surgical outcomesVAS-LP scoresPatient-reported satisfactionOverall patient satisfactionBody mass indexVisual analog scaleAfrican American patientsPatient-specific factorsPatient satisfaction measuresPerception of health
2017
Independent Association Between Preoperative Cognitive Status and Discharge Location After Surgery: A Strategy to Reduce Resource Use After Surgery for Deformity
Adogwa O, Elsamadicy AA, Sergesketter A, Vuong VD, Moreno J, Cheng J, Karikari IO, Bagley CA. Independent Association Between Preoperative Cognitive Status and Discharge Location After Surgery: A Strategy to Reduce Resource Use After Surgery for Deformity. World Neurosurgery 2017, 110: e67-e72. PMID: 29081391, DOI: 10.1016/j.wneu.2017.10.081.Peer-Reviewed Original ResearchConceptsNormal cognitive statusCognitive impairmentCognitive statusOlder patientsSLUMS scorePreoperative cognitive impairmentElective spinal surgeryPreoperative cognitive statusStandard deviation ageAdult degenerative scoliosisBaseline cognitive impairmentSevere cognitive impairmentMental status testsMild cognitive impairmentPostoperative lengthPreoperative scoresDeviation ageGeriatric patientsDegenerative scoliosisIndependent associationSpinal surgeryDeformity correctionPatientsSurgeryCognitive screeningThe Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion
Adogwa O, Elsamadicy AA, Sergesketter A, Oyeyemi D, Galan D, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion. World Neurosurgery 2017, 110: e266-e270. PMID: 29109065, DOI: 10.1016/j.wneu.2017.10.147.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCKD groupPatient demographicsKidney diseaseLumbar arthrodesisPreoperative chronic kidney diseaseInferior perioperative outcomesLumbar spine decompressionPostoperative complication profileLength of surgeryPostoperative complication rateEpisode of deliriumUrinary tract infectionDeep vein thrombosisBody mass indexIntensive care unitMajor academic institutionPerioperative complicationsPerioperative outcomesPostoperative complicationsPrimary endpointAdult patientsComplication rateLumbar decompressionPostoperative outcomesGeriatric comanagement reduces perioperative complications and shortens duration of hospital stay after lumbar spine surgery: a prospective single-institution experience.
Adogwa O, Elsamadicy AA, Vuong VD, Moreno J, Cheng J, Karikari IO, Bagley CA. Geriatric comanagement reduces perioperative complications and shortens duration of hospital stay after lumbar spine surgery: a prospective single-institution experience. Journal Of Neurosurgery Spine 2017, 27: 670-675. PMID: 28960161, DOI: 10.3171/2017.5.spine17199.Peer-Reviewed Original ResearchConceptsLumbar spine surgeryHospital stayPOSH cohortElderly patientsSpine surgeryGeriatric comanagementPerioperative complicationsComplex lumbar spine surgeryElective lumbar spine surgeryMedical comorbid conditionsSenior Health (POSH) programDays of dischargeElective spinal surgerySingle institution experienceMajority of patientsNursing home admissionLumbar fusion surgeryResults One hundred twentyMajor academic medical centerAdult degenerative scoliosisAcademic medical centerHospital complicationsSurgical screeningPostoperative complicationsBaseline characteristicsImpact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients
Elsamadicy AA, Reddy GB, Nayar G, Sergesketter A, Zakare-Fagbamila R, Karikari IO, Gottfried ON. Impact of Gender Disparities on Short-Term and Long-Term Patient Reported Outcomes and Satisfaction Measures After Elective Lumbar Spine Surgery: A Single Institutional Study of 384 Patients. World Neurosurgery 2017, 107: 952-958. PMID: 28743671, DOI: 10.1016/j.wneu.2017.07.082.Peer-Reviewed Original ResearchConceptsElective lumbar spine surgeryLumbar spine surgeryVisual analog scaleSpine surgeryMale cohortPerception of healthFemale cohortAnalog scaleMean changeBaseline patient-reported outcome measuresVisual analog scale leg painEuroQol 5 dimensions questionnairePatient-reported outcome measuresPatient-reported outcome instrumentsBaseline patient demographicsLonger hospital stayOswestry Disability IndexSingle institutional studyOverall patient satisfactionLong-term patientsPatient-reported outcomesPatient satisfaction measuresPaucity of dataSpine OutcomesDisability Index30-Day Readmission After Spine Surgery
Adogwa O, Elsamadicy AA, Han JL, Karikari IO, Cheng J, Bagley CA. 30-Day Readmission After Spine Surgery. Spine 2017, 42: 520-524. PMID: 28350632, DOI: 10.1097/brs.0000000000001779.Peer-Reviewed Original ResearchConceptsElective spine surgeryUnplanned readmissionSpine surgeryEarly readmissionHospital stayUnplanned early readmissionsCauses of readmissionDays of dischargeRetrospective cohort reviewMajority of patientsCommon primary reasonsPost-discharge careDuke University HospitalSkilled nursing facilitiesQuality of careNonsurgical complicationsRefractory painCohort reviewDischarge careLumbar decompressionSD ageEmergency departmentUniversity HospitalRisk factorsCommon causeImpact of Affective Disorders on Recovery of Baseline Function in Patients Undergoing Spinal Surgery: A Single Institution Study of 275 Patients
Nayar G, Elsamadicy AA, Zakare-Fagbamila R, Farquhar J, Gottfried ON. Impact of Affective Disorders on Recovery of Baseline Function in Patients Undergoing Spinal Surgery: A Single Institution Study of 275 Patients. World Neurosurgery 2017, 100: 69-73. PMID: 28057592, DOI: 10.1016/j.wneu.2016.12.098.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityDecompression, SurgicalElective Surgical ProceduresFemaleHumansLength of StayMaleMiddle AgedMood DisordersMultivariate AnalysisPatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsProspective StudiesRecovery of FunctionRegression AnalysisRetrospective StudiesRisk FactorsSelf ReportSpineConceptsDecompressive spinal surgeryIndependent risk factorSpinal surgeryAffective disordersRisk factorsOutcome measuresBaseline functionPatient-reported outcome measuresPoor baseline qualitySpinal surgery patientsWorse postoperative outcomesSingle-institution studyMain outcome measuresSelf-reported recoveryRegression analysisMultivariate regression analysisMajor academic institutionBaseline demographicsPerioperative variablesPostoperative outcomesSurgery patientsMore smokersSurgical outcomesPostoperative expectationsControl cohort
2016
The Effect of Patient Race on Extent of Functional Improvement After Cervical Spine Surgery
Elsamadicy A, Adogwa O, Reiser E, Fatemi P, Cheng J, Bagley C. The Effect of Patient Race on Extent of Functional Improvement After Cervical Spine Surgery. Spine 2016, 41: 822-826. PMID: 27128256, DOI: 10.1097/brs.0000000000001346.Peer-Reviewed Original ResearchConceptsNeck Disability IndexPatient-reported outcome measuresPhysical component scoreMental component scoreSF-12 mental component scoreSF-12 physical component scoreVisual analog pain scaleVAS neck painOutcome measuresWhite patientsSimilar improvementsDuke University Medical CenterPatient cohort 2Analog pain scaleAnterior cervical discectomyCervical spine surgeryNerve root injuryShort Form-12Clinical outcome dataLongitudinal cohort studyUniversity Medical CenterComponent scoresDisability IndexNeck painAdult patientsDo measures of surgical effectiveness at 1 year after lumbar spine surgery accurately predict 2-year outcomes?
Adogwa O, Elsamadicy AA, Han JL, Cheng J, Karikari I, Bagley CA. Do measures of surgical effectiveness at 1 year after lumbar spine surgery accurately predict 2-year outcomes? Journal Of Neurosurgery Spine 2016, 25: 689-696. PMID: 26722957, DOI: 10.3171/2015.8.spine15476.Peer-Reviewed Original ResearchConceptsTransforaminal lumbar interbody fusionLumbar spine surgeryAnterior lumbar interbody fusionLong-term outcomesLateral interbody fusionLumbar interbody fusionSpine surgeryInterbody fusionSurgical effectivenessOutcome measuresSF-36 physical component summary scorePhysical component summary scoreLongitudinal assessmentPatient-reported outcome instrumentsAchievement of MCIDMultiinstitutional prospective studyVAS leg painComponent summary scoresClinical outcome dataPatient-centered measuresLogistic regression modelingIneffective patient careInstitutional registryOutcomes RegistrySF-36
2015
Pretreatment of Depression Before Cervical Spine Surgery Improves Patients' Perception of Postoperative Health Status: A Retrospective, Single Institutional Experience
Elsamadicy AA, Adogwa O, Cheng J, Bagley C. Pretreatment of Depression Before Cervical Spine Surgery Improves Patients' Perception of Postoperative Health Status: A Retrospective, Single Institutional Experience. World Neurosurgery 2015, 87: 214-219. PMID: 26706296, DOI: 10.1016/j.wneu.2015.11.067.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntidepressive AgentsCervical VertebraeCohort StudiesDepressionDisability EvaluationDiskectomyFemaleHealth StatusHumansMaleMiddle AgedNeck PainPain MeasurementPatient SatisfactionPostoperative ComplicationsProspective StudiesRetrospective StudiesSpinal FusionSpineTreatment OutcomeConceptsNeck pain visual analog scalePain visual analog scaleNeck Disability IndexVisual analog scaleSF-12 mental component scoreSF-12 PCSMental component scoreSF-12 physical component scoreComponent scoresDuke University Medical CenterPatient-reported outcome measuresPostoperative health statusAnterior cervical discectomyCervical spine surgeryNerve root injurySingle institutional experiencePhysical component scoreShort Form-12Clinical outcome dataBoard-certified psychiatristHistory of depressionUniversity Medical CenterSimilar improvementsSignificant differencesDisability IndexPretreatment of Anxiety Before Cervical Spine Surgery Improves Clinical Outcomes: A Prospective, Single-Institution Experience
Adogwa O, Elsamadicy AA, Cheng J, Bagley C. Pretreatment of Anxiety Before Cervical Spine Surgery Improves Clinical Outcomes: A Prospective, Single-Institution Experience. World Neurosurgery 2015, 88: 625-630. PMID: 26585724, DOI: 10.1016/j.wneu.2015.11.014.Peer-Reviewed Original ResearchConceptsNeck Disability IndexNeck pain scoresVisual analog scaleSpine surgeryPain scoresPostoperative painClinical outcomesControl cohortAffective disordersDuke University Medical CenterAnxiety disordersVAS neck painLower postoperative painSF-12 PCSAnterior cervical discectomyCervical spine pathologyCervical spine surgeryNerve root injurySF-12 MCSSingle institution experienceShort Form-12Clinical outcome dataPatient reported outcomesBoard-certified psychiatristUniversity Medical CenterAssessing Patient Reported Outcomes Measures via Phone Interviews Versus Patient Self-Survey in the Clinic: Are We Measuring the Same Thing?
Adogwa O, Elsamadicy AA, Cheng J, Bagley C. Assessing Patient Reported Outcomes Measures via Phone Interviews Versus Patient Self-Survey in the Clinic: Are We Measuring the Same Thing? World Neurosurgery 2015, 87: 230-234. PMID: 26548832, DOI: 10.1016/j.wneu.2015.10.092.Peer-Reviewed Original ResearchConceptsOswestry Disability IndexPatient-reported outcomesBaseline PRO dataVisual analog scalePRO dataAnalog scalePhone interviewsBaseline Oswestry Disability IndexDuke University Medical CenterCoronary artery diseaseHistory of depressionUniversity Medical CenterRepeated-measures analysisVAS-BPVAS-LPBaseline painDisability IndexLeg painAdult patientsArtery diseaseBack painFunctional disabilityProspective studyEnrollment criteriaLumbar fusion