2024
Impact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis
Aghajanian S, Shafiee A, Athar M, Mohammadifard F, Goodarzi S, Esmailpur F, Elsamadicy A. Impact of Depression on Postoperative Medical and Surgical Outcomes in Spine Surgeries: A Systematic Review and Meta-Analysis. Journal Of Clinical Medicine 2024, 13: 3247. PMID: 38892958, PMCID: PMC11172961, DOI: 10.3390/jcm13113247.Peer-Reviewed Original ResearchNon-routine dischargeSpine surgerySurgical complicationsSurgical outcomesStatistically significant higher rateUrinary tract infectionSurgical site infectionDeep vein thrombosisLength of hospitalizationSystematic reviewNon-depressed controlsSignificantly higher ratesUrinary retentionPostoperative medicationTract infectionsPostoperative outcomesPulmonary embolismSite infectionSpinal surgeryVein thrombosisImpact of depressionPooled analysisDepressed patientsHematoma formationHospital length167 Association Between Safety-net Hospital Status and Postoperative Outcomes Following ACDF or PCDF for Cervical Spondylotic Myelopathy
Elsamadicy A, Sayeed S, Craft S, Sherman J, Reeves B, Koo A, Khalid S, Lo S, Shin J, Mendel E, Sciubba D. 167 Association Between Safety-net Hospital Status and Postoperative Outcomes Following ACDF or PCDF for Cervical Spondylotic Myelopathy. Neurosurgery 2024, 70: 40-40. DOI: 10.1227/neu.0000000000002809_167.Peer-Reviewed Original ResearchCervical spondylotic myelopathyNon-routine dischargeSafety-net hospital statusSafety-net hospitalACDF cohortSpondylotic myelopathyPostoperative outcomesAdverse eventsMultivariate analysisPosterior cervical decompressionAnterior cervical discectomyImpact postoperative outcomesProportion of patientsNational Inpatient Sample databaseRetrospective cohort studyPredictors of prolonged LOSInpatient Sample databaseNon-SNHsElective ACDFCervical decompressionCervical discectomyStudy patientsIndependent predictorsAdult patientsACDF
2023
Frailty and postoperative outcomes in brain tumor patients: a systematic review subdivided by tumor etiology
Qureshi H, Tabor J, Pickens K, Lei H, Vasandani S, Jalal M, Vetsa S, Elsamadicy A, Marianayagam N, Theriault B, Fulbright R, Qin R, Yan J, Jin L, O’Brien J, Morales-Valero S, Moliterno J. Frailty and postoperative outcomes in brain tumor patients: a systematic review subdivided by tumor etiology. Journal Of Neuro-Oncology 2023, 164: 299-308. PMID: 37624530, PMCID: PMC10522517, DOI: 10.1007/s11060-023-04416-1.Peer-Reviewed Original ResearchBrain tumor patientsTumor patientsPostoperative outcomesFrailty indexSystematic reviewBrain tumorsPrimary intracranial tumorsMethodsSystematic literature reviewPrognostic valueVestibular schwannomaPostsurgical outcomesBenign tumorsIntracranial tumorsLesion etiologyTumor outcomeExclusion criteriaMalignant lesionsPRISMA guidelinesPatientsConclusionOur reviewTumor pathologyUnique etiologyTumor typesFrailtyNeurosurgical oncologyEffects of delayed ambulation following posterior spinal fusion for adolescent idiopathic scoliosis: a single institutional study
Hengartner A, David W, Reeves B, Craft S, Boroumand S, Clappier M, Hansen J, Fernandez T, Koo A, Tuason D, DiLuna M, Elsamadicy A. Effects of delayed ambulation following posterior spinal fusion for adolescent idiopathic scoliosis: a single institutional study. Spine Deformity 2023, 11: 1127-1136. PMID: 37093449, DOI: 10.1007/s43390-023-00693-y.Peer-Reviewed Original ResearchConceptsPosterior spinal fusionAdolescent idiopathic scoliosisSpinal fusionPostoperative complicationsRisk factorsIdiopathic scoliosisMultivariate stepwise logistic regressionOral pain medicationTotal hospital lengthTwenty-nine patientsMethodsThe medical recordsSingle institutional studyStepwise logistic regressionMajor academic institutionHospital lengthHospital stayNine patientsPain medicationUnplanned readmissionIntraoperative variablesPatient demographicsPostoperative outcomesRBC transfusionHealthcare utilizationOperative timeA current review of spinal meningiomas: epidemiology, clinical presentation and management
Elsamadicy A, Reeves B, Craft S, Sherman J, Koo A, Sayeed S, Sarkozy M, Kolb L, Lo S, Shin J, Sciubba D, Mendel E. A current review of spinal meningiomas: epidemiology, clinical presentation and management. Journal Of Neuro-Oncology 2023, 161: 395-404. PMID: 36637710, DOI: 10.1007/s11060-023-04238-1.Peer-Reviewed Original ResearchConceptsSpinal meningiomasClinical presentationTumor developmentAdverse postoperative outcomesBenign spinal tumorsBenign spine tumorsRecent treatment recommendationsCharacteristic imaging findingsSubsequent tumor developmentPostoperative outcomesReceptor statusSpine tumorsImaging findingsSpinal tumorsCase reportTreatment recommendationsClinical evaluationClinical trialsGoogle Scholar searchOperative techniqueIntracranial meningiomasRadiation modalitiesSystematic reviewMeningiomasTumor genetics
2022
Association of inpatient opioid consumption on postoperative outcomes after open posterior spinal fusion for adult spine deformity
Elsamadicy A, Sandhu M, Reeves B, Freedman I, Koo A, Jayaraj C, Hengartner A, Havlik J, Hersh A, Pennington Z, Lo S, Shin J, Mendel E, Sciubba D. Association of inpatient opioid consumption on postoperative outcomes after open posterior spinal fusion for adult spine deformity. Spine Deformity 2022, 11: 439-453. PMID: 36350557, DOI: 10.1007/s43390-022-00609-2.Peer-Reviewed Original ResearchConceptsAdult spinal deformityInpatient opioid useProportion of patientsOpioid useAdverse eventsHigher MMESpinal fusionHospital costsMME consumptionPostoperative outcomesDischarge dispositionHospital admissionRisk factorsMultivariate analysisLong-term opioid useMethodsA retrospective cohort studyHigh opioid useInpatient opioid consumptionOpioid-related disordersPremier Healthcare DatabasePostoperative adverse eventsPostoperative opioid useRetrospective cohort studyHealthcare resource utilizationNon-routine discharge
2021
Comparison of frailty metrics and the Charlson Comorbidity Index for predicting adverse outcomes in patients undergoing surgery for spine metastases.
Hersh AM, Pennington Z, Hung B, Patel J, Goldsborough E, Schilling A, Feghali J, Antar A, Srivastava S, Botros D, Elsamadicy AA, Lo SL, Sciubba DM. Comparison of frailty metrics and the Charlson Comorbidity Index for predicting adverse outcomes in patients undergoing surgery for spine metastases. Journal Of Neurosurgery Spine 2021, 36: 849-857. PMID: 34826820, DOI: 10.3171/2021.8.spine21559.Peer-Reviewed Original ResearchMetastatic spinal tumor frailty indexCharlson Comorbidity IndexLength of stayNonroutine dischargePostoperative complicationsMFI-5Frailty metricsComorbidity indexPostoperative outcomesFrailty indexSpine metastasis patientsAdverse postoperative outcomesPatient demographic characteristicsProspective multicenter cohortHigh complication rateComprehensive cancer centerRobust independent predictorOutcomes of interestMedical comorbiditiesMetastasis surgeryPostoperative morbidityComplication rateMetastasis patientsRetrospective cohortIndependent predictorsImpact of race on outcomes and healthcare utilization following spinal fusion for adolescent idiopathic scoliosis
Elsamadicy AA, Koo AB, David WB, Freedman IG, Kundishora AJ, Hong CS, Sarkozy M, Sciubba DM, Kahle KT, DiLuna M. Impact of race on outcomes and healthcare utilization following spinal fusion for adolescent idiopathic scoliosis. Clinical Neurology And Neurosurgery 2021, 206: 106634. PMID: 33979695, DOI: 10.1016/j.clineuro.2021.106634.Peer-Reviewed Original ResearchConceptsPosterior spinal fusionPostoperative complicationsAdolescent idiopathic scoliosisPatient demographicsIdiopathic scoliosisAdolescent patientsSpine surgerySpinal fusionBlack cohortBaseline patient demographicsRate of complicationsMajority of patientsPosterior spine surgeryPosterior spinal surgeryMedian total costBaseline comorbiditiesHospital stayDischarge dispositionInpatient managementPostoperative outcomesBlood transfusionPrimary outcomeFemale patientsHealthcare utilizationHispanic patients
2020
Impact of Pulmonary Risk Factors on Postoperative Outcomes Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis
Elsamadicy A, Freedman I, Koo A, David W, Havlik J, Reeves B, Sarkozy M, Kundishora A, Sciubba D, Kahle K, DiLuna M. Impact of Pulmonary Risk Factors on Postoperative Outcomes Following Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis. Neurosurgery 2020, 67 DOI: 10.1093/neuros/nyaa447_591.Peer-Reviewed Original Research
2017
The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion
Adogwa O, Elsamadicy AA, Sergesketter A, Oyeyemi D, Galan D, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. The Impact of Chronic Kidney Disease on Postoperative Outcomes in Patients Undergoing Lumbar Decompression and Fusion. World Neurosurgery 2017, 110: e266-e270. PMID: 29109065, DOI: 10.1016/j.wneu.2017.10.147.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseCKD groupPatient demographicsKidney diseaseLumbar arthrodesisPreoperative chronic kidney diseaseInferior perioperative outcomesLumbar spine decompressionPostoperative complication profileLength of surgeryPostoperative complication rateEpisode of deliriumUrinary tract infectionDeep vein thrombosisBody mass indexIntensive care unitMajor academic institutionPerioperative complicationsPerioperative outcomesPostoperative complicationsPrimary endpointAdult patientsComplication rateLumbar decompressionPostoperative outcomesReduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Vuong VD, Lydon E, Behrens S, Cheng J, Bagley CA, Karikari IO. Reduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients. World Neurosurgery 2017, 107: 233-238. PMID: 28790002, DOI: 10.1016/j.wneu.2017.07.174.Peer-Reviewed Original ResearchConceptsReadmission ratesSmoking statusComplex spinal fusionSpinal fusionPostoperative complicationsPatient demographicsComplication rateSimilar postoperative complication ratesAdult spinal deformity patientsPostoperative complication rateSingle institutional studyBody mass indexElective spinal fusionPatients' smoking statusAdult spine deformitySpinal deformity patientsComplex spinal surgeryMajor academic institutionHospital stayPostoperative outcomesPrimary outcomeWound drainageMass indexOperative timeDeformity patientsRelationship Among Koenig Depression Scale and Postoperative Outcomes, Ambulation, and Perception of Pain in Elderly Patients (≥65 Years) Undergoing Elective Spinal Surgery for Adult Scoliosis
Adogwa O, Elsamadicy AA, Sergesketter AR, Black C, Tarnasky A, Ongele MO, Vuong VD, Khalid S, Cheng J, Bagley CA, Karikari IO. Relationship Among Koenig Depression Scale and Postoperative Outcomes, Ambulation, and Perception of Pain in Elderly Patients (≥65 Years) Undergoing Elective Spinal Surgery for Adult Scoliosis. World Neurosurgery 2017, 107: 471-476. PMID: 28826716, DOI: 10.1016/j.wneu.2017.07.165.Peer-Reviewed Original ResearchConceptsElective spinal surgeryAmbulation abilityElderly patientsHospital dischargeComplication rateHospital stayPostoperative outcomesVAS scoresSpinal surgeryDepression ScaleVisual analog scale scoreSignificant differencesElective spine surgeryInferior postoperative outcomesPreoperative gait speedAnalog scale scoreDepressed elderly patientsPatient-reported outcomesAdult degenerative scoliosisPerception of painBoard-certified geriatriciansPostoperative complicationsBaseline demographicsIntraoperative variablesPrimary outcomeImpact of Affective Disorders on Recovery of Baseline Function in Patients Undergoing Spinal Surgery: A Single Institution Study of 275 Patients
Nayar G, Elsamadicy AA, Zakare-Fagbamila R, Farquhar J, Gottfried ON. Impact of Affective Disorders on Recovery of Baseline Function in Patients Undergoing Spinal Surgery: A Single Institution Study of 275 Patients. World Neurosurgery 2017, 100: 69-73. PMID: 28057592, DOI: 10.1016/j.wneu.2016.12.098.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityDecompression, SurgicalElective Surgical ProceduresFemaleHumansLength of StayMaleMiddle AgedMood DisordersMultivariate AnalysisPatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsProspective StudiesRecovery of FunctionRegression AnalysisRetrospective StudiesRisk FactorsSelf ReportSpineConceptsDecompressive spinal surgeryIndependent risk factorSpinal surgeryAffective disordersRisk factorsOutcome measuresBaseline functionPatient-reported outcome measuresPoor baseline qualitySpinal surgery patientsWorse postoperative outcomesSingle-institution studyMain outcome measuresSelf-reported recoveryRegression analysisMultivariate regression analysisMajor academic institutionBaseline demographicsPerioperative variablesPostoperative outcomesSurgery patientsMore smokersSurgical outcomesPostoperative expectationsControl cohort
2016
Race as an Independent Predictor of Temporal Delay in Time to Diagnosis and Treatment in Patients with Cervical Stenosis: A Study of 133 Patients with Anterior Cervical Discectomy and Fusion
Elsamadicy AA, Adogwa O, Fialkoff J, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Race as an Independent Predictor of Temporal Delay in Time to Diagnosis and Treatment in Patients with Cervical Stenosis: A Study of 133 Patients with Anterior Cervical Discectomy and Fusion. World Neurosurgery 2016, 96: 107-110. PMID: 27567581, DOI: 10.1016/j.wneu.2016.08.070.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAnxietyBlack or African AmericanCervical VertebraeDecompression, SurgicalDelayed DiagnosisDepressionDiskectomyEthnicityFemaleHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisRetrospective StudiesRisk FactorsSex FactorsSpinal FusionSpinal StenosisTime-to-TreatmentWhite PeopleConceptsAnterior cervical discectomyVisual analog scaleCervical stenosisIndependent predictorsCervical discectomyPatient demographicsMultivariate analysisElective anterior cervical discectomyVAS neck pain scoresPatient-reported outcome measuresSignificant cervical stenosisSymptomatic cervical stenosisVAS neck painIndependent risk factorPostoperative complication rateWorse postoperative outcomesBody mass indexStandard deviation ageMajor academic medical centerHistory of depressionAcademic medical centerPreoperative painNeurological sequelaePain scoresPostoperative outcomes