2020
Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction.
Elsamadicy AA, Adil SM, Charalambous L, Drysdale N, Koo AB, Lee M, Kundishora AJ, Camara-Quintana J, Kolb L, Laurans M, Abbed K, Karikari IO. Independent Association Between Type of Intraoperative Blood Transfusion and Postoperative Delirium After Complex Spinal Fusion for Adult Deformity Correction. Spine 2020, 45: 268-274. PMID: 31996654, DOI: 10.1097/brs.0000000000003260.Peer-Reviewed Original ResearchConceptsIntraoperative blood transfusionComplex spinal fusionAllogenic blood transfusionPostoperative deliriumBlood transfusionSpinal fusionIndependent associationDeformity correctionMultivariate nominal-logistic regression analysisPrimary complex spinal fusionAdult spine deformity patientsAdult deformity correctionBetter overall patient careGreater complication risksRetrospective cohort studySpine deformity patientsOverall patient careNominal logistic regression analysisMajor academic institutionHospital stayCohort studyBlood lossPrimary outcomeComplication riskDeformity patients
2019
Reduced Influence of Affective Disorders on 6-Week and 3-Month Narcotic Refills After Primary Complex Spinal Fusions for Adult Deformity Correction: A Single-Institutional Study
Elsamadicy AA, Charalambous L, Adil SM, Drysdale N, Lee M, Koo AB, Chouairi F, Kundishora AJ, Camara-Quintana J, Qureshi T, Kolb L, Laurans M, Abbed K, Karikari IO. Reduced Influence of Affective Disorders on 6-Week and 3-Month Narcotic Refills After Primary Complex Spinal Fusions for Adult Deformity Correction: A Single-Institutional Study. World Neurosurgery 2019, 129: e311-e316. PMID: 31132486, DOI: 10.1016/j.wneu.2019.05.135.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionNarcotic refillsPain scoresSpinal fusionAffective disordersDeformity correctionNarcotic useDeformity patientsAD cohortPatient-reported pain scoresAdult spine deformity patientsAdult deformity correctionPostoperative pain scoresPostoperative complication ratePreoperative narcotic useHigher pain scoresSpinal deformity patientsSpine deformity patientsMajor academic institutionAmbulatory statusComplication ratePatient demographicsPrimary outcomePostoperative perceptionAssociation Between Preoperative Narcotic Use with Perioperative Complication Rates, Patient Reported Pain Scores, and Ambulatory Status After Complex Spinal Fusion (≥5 Levels) for Adult Deformity Correction
Elsamadicy AA, Drysdale N, Adil SM, Charalambous L, Lee M, Koo A, Freedman IG, Kundishora AJ, Camara-Quintana J, Qureshi T, Kolb L, Laurans M, Abbed K, Karikari IO. Association Between Preoperative Narcotic Use with Perioperative Complication Rates, Patient Reported Pain Scores, and Ambulatory Status After Complex Spinal Fusion (≥5 Levels) for Adult Deformity Correction. World Neurosurgery 2019, 128: e231-e237. PMID: 31009775, DOI: 10.1016/j.wneu.2019.04.107.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBone TransplantationDepressionFemaleHumansIntraoperative Neurophysiological MonitoringLaminectomyLength of StayMaleMiddle AgedMobility LimitationNarcoticsOsteotomyPainPain MeasurementPain, PostoperativePatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsPreoperative PeriodSpinal DiseasesSpinal FusionConceptsComplex spinal fusionPain scoresPerioperative complication ratePreoperative narcotic useComplication rateSpinal fusionAmbulatory statusNarcotic usePatient demographicsDeformity correctionPatient-reported pain scoresPrimary complex spinal fusionAdult deformity correctionLast pain scoreNon-user cohortsPostoperative pain scoresPostoperative complication rateHigher pain scoresPhysical therapy regimensPrevalence of depressionGreater mean ageUse of narcoticsMajor academic institutionAmbulatory dayPreoperative useReduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction
Elsamadicy AA, Camara-Quintana J, Kundishora AJ, Lee M, Freedman IG, Long A, Qureshi T, Laurans M, Tomak P, Karikari IO. Reduced Impact of Obesity on Short-Term Surgical Outcomes, Patient-Reported Pain Scores, and 30-Day Readmission Rates After Complex Spinal Fusion (≥7 Levels) for Adult Deformity Correction. World Neurosurgery 2019, 127: e108-e113. PMID: 30876992, DOI: 10.1016/j.wneu.2019.02.165.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBody Mass IndexComorbidityDiabetes MellitusDyslipidemiasElective Surgical ProceduresFemaleHeart DiseasesHumansHypertensionLaminectomyLength of StayMaleMiddle AgedObesityPain, PostoperativePatient ReadmissionPatient Reported Outcome MeasuresPostoperative ComplicationsPrevalencePulmonary Disease, Chronic ObstructiveRetrospective StudiesSpinal DiseasesSpinal FusionTreatment OutcomeUnited StatesYoung AdultConceptsPatient-reported pain scoresComplex spinal fusionPain scoresImpact of obesityReadmission ratesSurgical outcomesDeformity correctionSpinal fusionAmbulatory statusPatient demographicsComplication ratePreoperative body mass indexPrimary complex spinal fusionShort-term surgical outcomesAdult deformity correctionInferior surgical outcomesPostoperative complication profileLength of surgeryPostoperative complication ratePrevalence of obesityBody mass indexPatient-reported outcomesComplex spinal surgeryPaucity of dataMajor academic institutionIntraoperative ketamine may increase risk of post-operative delirium after complex spinal fusion for adult deformity correction
Elsamadicy AA, Charalambous LT, Sergesketter AR, Drysdale N, Adil SM, Freedman IG, Williamson T, Kundishora AJ, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Intraoperative ketamine may increase risk of post-operative delirium after complex spinal fusion for adult deformity correction. Journal Of Spine Surgery 2019, 5: 79-87. PMID: 31032442, PMCID: PMC6465460, DOI: 10.21037/jss.2018.12.10.Peer-Reviewed Original ResearchPost-operative deliriumMultivariate nominal-logistic regression analysisComplex spinal fusionIntraoperative ketamine administrationIntraoperative ketamineNominal logistic regression analysisSpinal fusionPatient demographicsKetamine administrationDeformity correctionPrimary complex spinal fusionPost-operative complication rateAdult spine deformity patientsAdult deformity correctionBetter overall patient carePostoperative complication profileProportion of patientsLength of surgeryPost-operative painPost-operative outcomesSpine deformity patientsComplex spinal surgeryOverall patient careRegression analysisMajor academic institutionRate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction.
Elsamadicy AA, Lubkin DT, Sergesketter AR, Adil SM, Charalambous LT, Drysdale N, Williamson T, Camara-Quintana J, Abd-El-Barr MM, Goodwin CR, Karikari IO. Rate of instrumentation changes on postoperative and follow-up radiographs after primary complex spinal fusion (five or more levels) for adult deformity correction. Journal Of Neurosurgery Spine 2019, 30: 376-381. PMID: 30641841, DOI: 10.3171/2018.9.spine18686.Peer-Reviewed Original ResearchConceptsPrimary complex spinal fusionComplex spinal fusionSpinal fusionSpine surgeryDeformity correctionAdult deformity correctionCost-conscious healthcareMethodsThe medical recordsPostoperative complication rateMean lengthBody mass indexFollow-up radiographsRevision of surgeryComplex spine surgeryMajor academic institutionHospital stayAdult patientsComplication ratePatient demographicsReadmission ratesBlood lossPrimary outcomeMass indexEarly radiographsPostoperative radiographs
2018
Correlation of 2-year SRS-22r and ODI patient-reported outcomes with 5-year patient-reported outcomes after complex spinal fusion: a 5-year single-institution study of 118 patients.
Adogwa O, Karikari IO, Elsamadicy AA, Sergesketter AR, Galan D, Bridwell KH. Correlation of 2-year SRS-22r and ODI patient-reported outcomes with 5-year patient-reported outcomes after complex spinal fusion: a 5-year single-institution study of 118 patients. Journal Of Neurosurgery Spine 2018, 29: 422-428. PMID: 29979138, DOI: 10.3171/2018.2.spine171142.Peer-Reviewed Original ResearchConceptsPatient-reported outcomesComplex spinal fusionSpinal fusionLong-term patient-reported outcomesBaseline patient-reported outcomesMental healthSRS-22r domainsSingle-institution studyLack of patientsSRS-22rAdult patientsAmbispective studyIntraoperative variablesPatient demographicsPrimary outcomeGreater absolute changeRevision surgeryRadiographic parametersProspective collectionCobb angleSpinal arthrodesisIliac fixationPatientsPRO dataPRO instruments
2017
Reduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Vuong VD, Lydon E, Behrens S, Cheng J, Bagley CA, Karikari IO. Reduced Impact of Smoking Status on 30-Day Complication and Readmission Rates After Elective Spinal Fusion (≥3 Levels) for Adult Spine Deformity: A Single Institutional Study of 839 Patients. World Neurosurgery 2017, 107: 233-238. PMID: 28790002, DOI: 10.1016/j.wneu.2017.07.174.Peer-Reviewed Original ResearchConceptsReadmission ratesSmoking statusComplex spinal fusionSpinal fusionPostoperative complicationsPatient demographicsComplication rateSimilar postoperative complication ratesAdult spinal deformity patientsPostoperative complication rateSingle institutional studyBody mass indexElective spinal fusionPatients' smoking statusAdult spine deformitySpinal deformity patientsComplex spinal surgeryMajor academic institutionHospital stayPostoperative outcomesPrimary outcomeWound drainageMass indexOperative timeDeformity patientsImpact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single-Institutional Study of 643 Adult Patients with Spinal Deformity
Elsamadicy AA, Adogwa O, Lydon E, Reddy G, Kaakati R, Sergesketter A, Gottfried ON, Karikari IO. Impact of Intraoperative Monitoring During Elective Complex Spinal Fusions (≥4 Levels) on 30-Day Complication and Readmission Rates: A Single-Institutional Study of 643 Adult Patients with Spinal Deformity. World Neurosurgery 2017, 101: 283-288. PMID: 28192259, DOI: 10.1016/j.wneu.2017.02.002.Peer-Reviewed Original ResearchConceptsComplex spinal fusionIntraoperative monitoringPostoperative complicationsReadmission ratesSpinal fusionAdult patientsSpinal deformityUse of IOMIntensive care unit transferSimilar postoperative complicationsBody mass indexOverall surgical outcomeSpinal cord injuryMajor academic institutionIOM useHospital stayComplication rateNerve injuryPatient demographicsTranscranial motorPrimary outcomeMass indexOperative timeSensorimotor deficitsSmoking status
2016
Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients
Elsamadicy AA, Adogwa O, Sergesketter A, Hobbs C, Behrens S, Mehta AI, Vasquez RA, Cheng J, Bagley CA, Karikari IO. Impact of Race on 30-Day Complication Rates After Elective Complex Spinal Fusion (≥5 Levels): A Single Institutional Study of 446 Patients. World Neurosurgery 2016, 99: 418-423. PMID: 28003170, DOI: 10.1016/j.wneu.2016.12.029.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanElective Surgical ProceduresEquipment FailureEthnicityFemaleHumansIntensive Care UnitsIntraoperative ComplicationsLength of StayMaleMiddle AgedOperative TimePain, PostoperativePatient ReadmissionPostoperative ComplicationsRetrospective StudiesSpinal DiseasesSpinal FusionSurgical Wound DehiscenceUrinary Tract InfectionsWhite PeopleConceptsComplex spinal fusionPostoperative complicationsComplication rateSpinal fusionPatient demographicsReadmission ratesSimilar postoperative complicationsSingle institutional studyUrinary tract infectionSpinal fusion outcomesBody mass indexComplex spinal surgeryMajor academic institutionHospital stayTract infectionsAdult patientsPrimary outcomeWhite patientsBlack patientsOperative timeMass indexSurgical outcomesMedical recordsPatient raceSpinal surgeryImpact of Age on Change in Self-Image 5 Years After Complex Spinal Fusion (≥5 Levels)
Elsamadicy AA, Adogwa O, Sergesketter A, Behrens S, Hobbs C, Bridwell KH, Karikari IO. Impact of Age on Change in Self-Image 5 Years After Complex Spinal Fusion (≥5 Levels). World Neurosurgery 2016, 97: 112-116. PMID: 27713066, DOI: 10.1016/j.wneu.2016.09.095.Peer-Reviewed Original ResearchConceptsPatient-reported outcomesComplex spinal fusionImpact of ageSpinal fusionComplication ratePreoperative variablesSignificant differencesImportant patient-reported outcomeFusion levelsPostoperative complication rateTypes of complicationsDeformity correction surgeryStandard deviation numberSRS-22rAdult patientsBaseline characteristicsEffect of ageIntraoperative variablesPatient demographicsSelf-image scoresYounger patientsPrimary outcomeCorrective surgeryCorrection surgeryPatients' perceptions