2022
Assessment of Spinal Metastases Surgery Risk Stratification Tools in Breast Cancer by Molecular Subtype
Duvall J, Massaad E, Siraj L, Kiapour A, Connolly I, Hadzipasic M, Elsamadicy A, Williamson T, Shankar G, Schoenfeld A, Fourman M, Shin J. Assessment of Spinal Metastases Surgery Risk Stratification Tools in Breast Cancer by Molecular Subtype. Neurosurgery 2022, 92: 83-91. PMID: 36305664, PMCID: PMC10158884, DOI: 10.1227/neu.0000000000002180.Peer-Reviewed Original ResearchConceptsHuman epidermal growth factor receptor 2Epidermal growth factor receptor 2Triple-negative breast cancerGrowth factor receptor 2Factor receptor 2Breast cancerHazard ratioSpine metastasesMolecular subtypesReceptor 2Retrospective multi-institutional studyHormone receptorsBreast cancer molecular subtypesPostoperative systemic therapySystemic treatment plansPoor physical activityRisk stratification toolSpinal metastasis surgeryCancer molecular subtypesMulti-institutional studyMassachusetts General HospitalMolecular featuresPostoperative chemotherapyBrain metastasesEndocrine therapy
2017
Leptomeningeal disease: current diagnostic and therapeutic strategies
Nayar G, Ejikeme T, Chongsathidkiet P, Elsamadicy AA, Blackwell KL, Clarke JM, Lad SP, Fecci PE. Leptomeningeal disease: current diagnostic and therapeutic strategies. Oncotarget 2017, 5: 73312-73328. PMID: 29069871, PMCID: PMC5641214, DOI: 10.18632/oncotarget.20272.Peer-Reviewed Original ResearchLeptomeningeal diseaseT1-weighted magnetic resonance imagingCerebrospinal fluid cytologyLate-stage complicationsNovel therapeutic interventionsMagnetic resonance imagingLeptomeningeal spreadMedian survivalNeurological deficitsPrimary malignancyObstructive hydrocephalusSystemic diseaseCancer patientsLung cancerTreatment modalitiesFluid cytologyBreast cancerRadiation therapyTherapeutic strategiesTherapeutic interventionsMalignant cellsResonance imagingYounger ageEarly detectionDisease