2022
A new lineage of Galapagos giant tortoises identified from museum samples
Jensen E, Quinzin M, Miller J, Russello M, Garrick R, Edwards D, Glaberman S, Chiari Y, Poulakakis N, Tapia W, Gibbs J, Caccone A. A new lineage of Galapagos giant tortoises identified from museum samples. Heredity 2022, 128: 261-270. PMID: 35217806, PMCID: PMC8987048, DOI: 10.1038/s41437-022-00510-8.Peer-Reviewed Original ResearchConceptsGalapagos giant tortoisesMitochondrial control regionGiant tortoisesSingle nucleotide polymorphismsControl regionMuseum samplesGenome-wide single nucleotide polymorphismsDivergent mitochondrial lineagesSingle mitochondrial haplotypeContemporary populationsIconic radiationMitochondrial lineagesAdditional lineagesMitochondrial haplotypesNuclear markersSan CristóbalSecond lineageMicrosatellite lociNew lineagePinta IslandSame cladeEvolutionary processesLineagesGalapagos ArchipelagoEarly evolution
2018
Temporal Mitogenomics of the Galapagos Giant Tortoise from Pinzón Reveals Potential Biases in Population Genetic Inference
Jensen E, Miller J, Edwards D, Garrick R, Tapia W, Caccone A, Russello M. Temporal Mitogenomics of the Galapagos Giant Tortoise from Pinzón Reveals Potential Biases in Population Genetic Inference. Journal Of Heredity 2018, 109: 631-640. PMID: 29659893, DOI: 10.1093/jhered/esy016.Peer-Reviewed Original Research
2015
Hybridization masks speciation in the evolutionary history of the Galápagos marine iguana
MacLeod A, Rodríguez A, Vences M, Orozco-terWengel P, García C, Trillmich F, Gentile G, Caccone A, Quezada G, Steinfartz S. Hybridization masks speciation in the evolutionary history of the Galápagos marine iguana. Proceedings Of The Royal Society B 2015, 282: 20150425. PMID: 26041359, PMCID: PMC4590447, DOI: 10.1098/rspb.2015.0425.Peer-Reviewed Original ResearchConceptsGalápagos marine iguanasEvolutionary historyMarine iguanasIncipient speciationStrong population structureGenome-wide analysisGalápagos land iguanasCommon gene poolDepth genome-wide analysisSpeciation eventsIsland speciationSister lineageEvolutionary potentialFrequent hybridizationExtant populationsLocal adaptationPhylogenetic treeGene poolSister groupPopulation structureVariable markersLand iguanasEvolutionary processesSame islandNearby islands
2014
Lineage fusion in Galápagos giant tortoises
Garrick R, Benavides E, Russello M, Hyseni C, Edwards D, Gibbs J, Tapia W, Ciofi C, Caccone A. Lineage fusion in Galápagos giant tortoises. Molecular Ecology 2014, 23: 5276-5290. PMID: 25223395, DOI: 10.1111/mec.12919.Peer-Reviewed Original ResearchConceptsLineage fusionGiant tortoise speciesGalápagos giant tortoisesWidespread introgressive hybridizationLong generation timesWolf VolcanoCryptic lineagesReticulate evolutionIntrogressive hybridizationLineage splittingMicrosatellite dataGalápagos tortoisesPopulation geneticsEvolutionary phenomenaMate selectivityTortoise speciesGiant tortoisesLineagesGeneration timeRapid extinctionTortoisesPurebred femalesFusionIslandsHistorical reconstruction
2012
Genetic rediscovery of an ‘extinct’ Galápagos giant tortoise species
Garrick R, Benavides E, Russello M, Gibbs J, Poulakakis N, Dion K, Hyseni C, Kajdacsi B, Márquez, Bahan S, Ciofi C, Tapia W, Caccone A. Genetic rediscovery of an ‘extinct’ Galápagos giant tortoise species. Current Biology 2012, 22: r10-r11. PMID: 22240469, DOI: 10.1016/j.cub.2011.12.004.Peer-Reviewed Original ResearchConceptsFloreana IslandHybrid individualsGiant tortoise speciesUnique evolutionary lineagesGiant Galápagos tortoisesCaptive breeding programsEvolutionary lineagesGalápagos tortoisesHybrid offspringExtinct speciesGenetic footprintsTortoise speciesBreeding programsGalápagos IslandsGenetic signaturesExtant individualsIsabela IslandGenomeSpeciesMixed ancestryTortoisesAncestryIslandsLineagesLikely mechanism
2010
Genetic Differentiation between Marine Iguanas from Different Breeding Sites on the Island of Santa Fé (Galápagos Archipelago)
Lanterbecq D, Glaberman S, Vitousek M, Steinfartz S, Benavides E, Wikelski M, Caccone A. Genetic Differentiation between Marine Iguanas from Different Breeding Sites on the Island of Santa Fé (Galápagos Archipelago). Journal Of Heredity 2010, 101: 663-675. PMID: 20538757, DOI: 10.1093/jhered/esq067.Peer-Reviewed Original ResearchConceptsMarine iguanasGenetic diversitySex-biased dispersalMitochondrial control regionMitochondrial DNA markersGalápagos marine iguanasSanta FéDifferent breeding sitesSouthern sitesGenetic differentiationEvolutionary signalGenetic structureMicrosatellite lociDNA markersControl regionGenetic variationGenetic patternsBreeding sitesLittle differentiationBase pairsNeighboring islandsIguanasDiversitySampling sitesDifferentiation
2009
Progressive colonization and restricted gene flow shape island-dependent population structure in Galápagos marine iguanas (Amblyrhynchus cristatus)
Steinfartz S, Glaberman S, Lanterbecq D, Russello M, Rosa S, Hanley T, Marquez C, Snell H, Snell H, Gentile G, Dell'Olmo G, Powell A, Caccone A. Progressive colonization and restricted gene flow shape island-dependent population structure in Galápagos marine iguanas (Amblyrhynchus cristatus). BMC Ecology And Evolution 2009, 9: 297. PMID: 20028547, PMCID: PMC2807874, DOI: 10.1186/1471-2148-9-297.Peer-Reviewed Original ResearchConceptsComplete mitochondrial control regionMarine iguanasGene flowPopulation structureMarine iguana populationsHistorical gene flowNuclear gene flowMicrosatellite genetic diversityStrong genetic differentiationMale-biased dispersalMitochondrial control regionRecent population expansionBayesian cluster analysisGalápagos marine iguanasHaplotype distribution patternsDistinct genetic clustersPast genetic studiesGenetic differentiationWestern islandsFST estimatesIguana populationsFounder eventsFST analysisDifferent inheritance patternsGenetic clustersMorphometrics Parallel Genetics in a Newly Discovered and Endangered Taxon of Galápagos Tortoise
Chiari Y, Hyseni C, Fritts T, Glaberman S, Marquez C, Gibbs J, Claude J, Caccone A. Morphometrics Parallel Genetics in a Newly Discovered and Endangered Taxon of Galápagos Tortoise. PLOS ONE 2009, 4: e6272. PMID: 19609441, PMCID: PMC2707613, DOI: 10.1371/journal.pone.0006272.Peer-Reviewed Original ResearchConceptsGalápagos tortoisesGenetic variationGenetic distinctionTortoise populationsNon-neutral lociStrong genetic differentiationComplex heritable traitsDiagnostic morphological charactersShell morphologyShell shape variationGenetic differentiationMitochondrial dataMonophyletic lineageMorphological charactersGiant tortoisesHeritable traitGenetic dataMost islandsSanta CruzMolecular studiesShell shapeTurtle shellTortoisesLineagesParallel Genetic
2008
Historical DNA analysis reveals living descendants of an extinct species of Galápagos tortoise
Poulakakis N, Glaberman S, Russello M, Beheregaray LB, Ciofi C, Powell JR, Caccone A. Historical DNA analysis reveals living descendants of an extinct species of Galápagos tortoise. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 15464-15469. PMID: 18809928, PMCID: PMC2563078, DOI: 10.1073/pnas.0805340105.Peer-Reviewed Original ResearchConceptsMuseum specimensHistorical DNA analysisDiversification of organismsCaptive breeding programsIsland of FloreanaModern DNA techniquesMicrosatellite dataGalápagos tortoisesConservation biologyMitochondrial DNANatural selectionExtinct speciesExtinct taxaBreeding programsGiant tortoisesIntense harvestingGenetic analysisGenetic dataGalápagos ArchipelagoTortoise populationsDNA techniquesHuman exploitationNearby islandsEnough individualsSpeciesColonization and diversification of Galpagos terrestrial fauna: a phylogenetic and biogeographical synthesis
Parent C, Caccone A, Petren K. Colonization and diversification of Galpagos terrestrial fauna: a phylogenetic and biogeographical synthesis. Philosophical Transactions Of The Royal Society B Biological Sciences 2008, 363: 3347-3361. PMID: 18782729, PMCID: PMC2607378, DOI: 10.1098/rstb.2008.0118.Peer-Reviewed Original ResearchConceptsTerrestrial faunaPhylogenetic studiesDivergence of populationsSimilar geological historyDistinct evolutionary historiesMolecular phylogenetic studiesRemote oceanic islandsRange of organismsStudy of diversificationHabitat specializationBiogeographical synthesisGeological historyLow vagilityDiverse habitatsEvolutionary historyGeological formationsOceanic islandsGroup of islandsGalápagos IslandsRemarkable settingUnique assemblageComparable climateEvolutionary processesFaunaIslands
2007
Lonesome George is not alone among Galápagos tortoises
Russello MA, Beheregaray LB, Gibbs JP, Fritts T, Havill N, Powell JR, Caccone A. Lonesome George is not alone among Galápagos tortoises. Current Biology 2007, 17: r317-r318. PMID: 17470342, DOI: 10.1016/j.cub.2007.03.002.Peer-Reviewed Original ResearchGiant Galápagos tortoises; molecular genetic analyses identify a trans-island hybrid in a repatriation program of an endangered taxon
Milinkovitch MC, Monteyne D, Russello M, Gibbs JP, Snell HL, Tapia W, Marquez C, Caccone A, Powell JR. Giant Galápagos tortoises; molecular genetic analyses identify a trans-island hybrid in a repatriation program of an endangered taxon. BMC Ecology And Evolution 2007, 7: 2. PMID: 17302982, PMCID: PMC1820773, DOI: 10.1186/1472-6785-7-2.Peer-Reviewed Original ResearchConceptsMolecular genetic analysisGenetic analysisIsland of EspañolaEffective population sizeGalápagos tortoisesGenetic integrityConservation significanceReproductive successHuman transportMicrosatellite allelesPopulation sizeTaxaSex ratioRepatriation programMajor islandsTortoisesFemale tortoisesSingle contaminationBreedersFurther contaminationIslandsHybridsPinzónContaminationLinage
2006
Phylogeographic History and Gene Flow Among Giant Galápagos Tortoises on Southern Isabela Island
Ciofi C, Wilson GA, Beheregaray LB, Marquez C, Gibbs JP, Tapia W, Snell HL, Caccone A, Powell JR. Phylogeographic History and Gene Flow Among Giant Galápagos Tortoises on Southern Isabela Island. Genetics 2006, 172: 1727-1744. PMID: 16387883, PMCID: PMC1456292, DOI: 10.1534/genetics.105.047860.Peer-Reviewed Original ResearchConceptsDispersal eventsMitochondrial DNA control region sequencesGalápagos giant tortoisesLimited dispersal abilityRecent dispersal eventsControl region sequencesGiant Galápagos tortoisesMultilocus genotyping methodsLand bridge formationMovement of organismsEffects of vicarianceRapid population declineIslands of IsabelaLineage sortingClade analysisPhylogeographic historyGene flowDispersal abilityGenetic divergenceGalápagos tortoisesMicrosatellite lociPhylogeographic inferenceSouthern Isabela IslandTaxonomic distinctionGiant tortoises
2004
Extreme difference in rate of mitochondrial and nuclear DNA evolution in a large ectotherm, Galápagos tortoises
Caccone A, Gentile G, Burns CE, Sezzi E, Bergman W, Ruelle M, Saltonstall K, Powell JR. Extreme difference in rate of mitochondrial and nuclear DNA evolution in a large ectotherm, Galápagos tortoises. Molecular Phylogenetics And Evolution 2004, 31: 794-798. PMID: 15062813, DOI: 10.1016/j.ympev.2004.02.004.Peer-Reviewed Original ResearchConceptsGalápagos tortoisesUnusual reproductive biologyKb of mtDNANuclear DNA evolutionEffective population sizeGiant Galápagos tortoisesRate of evolutionMtDNA divergenceMtDNA evolutionBiogeographic historyDNA evolutionMolecular evolutionNeutral theoryReproductive biologyLarge ectothermsNuclear DNAEctothermic animalsPopulation sizeSilent substitutionsNucDNAMtDNAKbTortoisesDivergenceExtreme differencesGiant tortoises are not so slow: Rapid diversification and biogeographic consensus in the Galápagos
Beheregaray L, Gibbs J, Havill N, Fritts T, Powell J, Caccone A. Giant tortoises are not so slow: Rapid diversification and biogeographic consensus in the Galápagos. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 6514-6519. PMID: 15084743, PMCID: PMC404076, DOI: 10.1073/pnas.0400393101.Peer-Reviewed Original ResearchConceptsGiant Galápagos tortoisesGalápagos tortoisesGreat natural laboratoryGenetic variationDivergent monophyletic cladesHistory of diversificationIsolated oceanic archipelagoPatterns of colonizationBiogeographic predictionsEvolutionary diversificationGene flowEndemic haplotypesExtant populationsLimited dispersalOceanic archipelagosBiogeographic patternsEvolutionary eventsBiological diversificationMonophyletic cladeMtDNA sequencesRapid diversificationGenetic interchangeRange expansionOlder islandsGiant tortoisesGenetic analysis of a successful repatriation programme: giant Galpagos tortoises
Milinkovitch M, Monteyne D, Gibbs J, Fritts T, Tapia W, Snell H, Tiedemann R, Caccone A, Powell J. Genetic analysis of a successful repatriation programme: giant Galpagos tortoises. Proceedings Of The Royal Society B 2004, 271: 341-345. PMID: 15101691, PMCID: PMC1691607, DOI: 10.1098/rspb.2003.2607.Peer-Reviewed Original ResearchConceptsGenetic variationIsland of EspañolaGiant Galápagos tortoisesMicrosatellite DNA markersNatural populationsGalápagos tortoisesDNA markersNatural habitatsSitu reproductionBreeding programsGenetic analysisRepatriation programBreedersTortoisesOffspringFurther lossHabitatsTaxaPaternitySpeciesCaptivityReproductionPopulationIslandsVariation
2003
Genes Record a Prehistoric Volcano Eruption in the Galápagos
Beheregaray L, Ciofi C, Geist D, Gibbs J, Caccone A, Powell J. Genes Record a Prehistoric Volcano Eruption in the Galápagos. Science 2003, 302: 75-75. PMID: 14526072, DOI: 10.1126/science.1087486.Peer-Reviewed Original Research
2002
Microsatellite analysis of genetic divergence among populations of giant Galápagos tortoises
Ciofi C, Milinkovitch M, Gibbs J, Caccone A, Powell J. Microsatellite analysis of genetic divergence among populations of giant Galápagos tortoises. Molecular Ecology 2002, 11: 2265-2283. PMID: 12406238, DOI: 10.1046/j.1365-294x.2002.01617.x.Peer-Reviewed Original ResearchConceptsGiant Galápagos tortoisesGenetic divergenceGalápagos tortoisesIsland populationsVolcan WolfIndividual island populationsIslands of IsabelaGene flowAdaptive differentiationGenetic structureMtDNA diversityExtant populationsColonization eventsEvolutionary historyMicrosatellite lociDifferent taxaAllelic similarityHeavy exploitationDNA workMicrosatellite analysisDeterministic threatsDistinct populationsTortoisesInteresting modelDivergence