2009
Intravenous mesenchymal stem cell therapy for traumatic brain injury.
Harting M, Jimenez F, Xue H, Fischer U, Baumgartner J, Dash P, Cox C. Intravenous mesenchymal stem cell therapy for traumatic brain injury. Journal Of Neurosurgery 2009, 110: 1189-97. PMID: 19301973, PMCID: PMC2889620, DOI: 10.3171/2008.9.jns08158.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryMesenchymal stem cell therapyArterial circulationStem cell therapyWeeks postinfusionFunctional recoveryCell therapyPulmonary microvasculatureBrain injuryCortical impact traumatic brain injuryPulmonary first-pass effectImpact traumatic brain injuryIntravenous MSC therapyRecovery of motorCognitive function recoveryFirst-pass effectMeasurements of motorMSC infusionCerebral parenchymaFunction recoveryIntravenous infusionMSC therapyPreclinical promiseFunctional improvementCarotid artery
2005
Resuscitation-Induced Gut Edema and Intestinal Dysfunction
Moore-Olufemi S, Xue H, Attuwaybi B, Fischer U, Harari Y, Oliver D, Weisbrodt N, Allen S, Moore F, Stewart R, Laine G, Cox C. Resuscitation-Induced Gut Edema and Intestinal Dysfunction. Journal Of Trauma And Acute Care Surgery 2005, 58: 264-270. PMID: 15706186, DOI: 10.1097/01.ta.0000133571.64393.d2.Peer-Reviewed Original ResearchConceptsMesenteric venous hypertensionGut edemaIntra-abdominal hypertensionVenous hypertensionIntestinal transitGroup BAltered gut barrier functionIschemia/reperfusion injuryBarrier functionGut barrier functionML/Mucosal injuryMyeloperoxidase activityFluid resuscitationIntestinal dysfunctionMucosal permeabilityReperfusion injurySham surgeryGut motilityGut functionHypertensionGroup AEdemaTissue resistanceInjury measurements