Association of increased interferon‐inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus
Feng X, Wu H, Grossman J, Hanvivadhanakul P, FitzGerald J, Park G, Dong X, Chen W, Kim M, Weng H, Furst D, Gorn A, McMahon M, Taylor M, Brahn E, Hahn B, Tsao B. Association of increased interferon‐inducible gene expression with disease activity and lupus nephritis in patients with systemic lupus erythematosus. Arthritis & Rheumatism 2006, 54: 2951-2962. PMID: 16947629, DOI: 10.1002/art.22044.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedFemaleGene Expression RegulationHumansLupus Erythematosus, SystemicLupus NephritisMaleMiddle AgedPolymerase Chain ReactionReference ValuesRheumatic DiseasesRNAConceptsSystemic lupus erythematosus patientsSystemic lupus erythematosusActive renal diseaseLupus nephritis patientsIFN scoreDisease activityLupus erythematosusNephritis patientsLupus nephritisPresence of anti-double-stranded DNARenal diseaseNormal controlsPhysician Global Assessment scoreAnti-dsDNA antibody positivityAnti-double-stranded DNAHigher IFN scoresInactive lupus nephritisSafety of EstrogensGlobal Assessment scoreAssociated with neurological manifestationsAssociated with proteinuriaLupus nephritis therapyPeripheral blood cellsRheumatic disease controlsExpression levels