Michelle H. Kim, MD, MS, FACS
she/her/hers
Assistant Professor of Surgery (Transplant)Cards
About
Research
Publications
2023
ASO Visual Abstract: The Current State of Liver Transplantation for Colorectal Liver Metastases in the United States: A Call for Standardized Reporting
Sasaki K, Ruffolo L, Kim M, Fujiki M, Hashimoto K, Imaoka Y, Melcher M, Aucejo F, Tomiyama K, Hernandez-Alejandro R. ASO Visual Abstract: The Current State of Liver Transplantation for Colorectal Liver Metastases in the United States: A Call for Standardized Reporting. Annals Of Surgical Oncology 2023, 30: 2780-2781. DOI: 10.1245/s10434-023-13234-8.Peer-Reviewed Original ResearchThe Current State of Liver Transplantation for Colorectal Liver Metastases in the United States: A Call for Standardized Reporting
Sasaki K, Ruffolo L, Kim M, Fujiki M, Hashimoto K, Imaoka Y, Melcher M, Aucejo F, Tomiyama K, Hernandez-Alejandro R. The Current State of Liver Transplantation for Colorectal Liver Metastases in the United States: A Call for Standardized Reporting. Annals Of Surgical Oncology 2023, 30: 2769-2777. PMID: 36719568, PMCID: PMC9888331, DOI: 10.1245/s10434-023-13147-6.Peer-Reviewed Original ResearchConceptsColorectal liver metastasesLiving donor LTLiver transplantationLiver metastasesNonresectable colorectal liver metastasesSurvival rateTime of LTOverall survival rateMELD-Na scoreDDLT groupLT patientsTransplant center characteristicsOncological historyDisease-freeTherapeutic optionsPatient selectionLiver tumorsHepatocellular carcinomaTransplant oncologyU.S. transplant centersPosttransplant outcomesSharing databaseTransplant centersUNOS dataPatients
2022
335.5: Has the Risk of Liver Re-Transplantation Improved Over the Two Decades? A UNOS Data Analysis
Kim M, Melcher M, Kirchner V, Gallo A, Bonham C, Esquivel C, Sasaki K. 335.5: Has the Risk of Liver Re-Transplantation Improved Over the Two Decades? A UNOS Data Analysis. Transplantation 2022, 106: s294-s294. DOI: 10.1097/01.tp.0000886948.87367.56.Peer-Reviewed Original Research
2021
Assessment of the global practice of living donor liver transplantation
Emamaullee J, Conrad C, Kim M, Goldbeck C, Kwon Y, Singh P, Niemann C, Sher L, Genyk Y. Assessment of the global practice of living donor liver transplantation. Transplant International 2021, 34: 1914-1927. PMID: 34165829, DOI: 10.1111/tri.13960.Peer-Reviewed Original ResearchConceptsDonor liver transplantationLiver transplantationComplex anatomical variationsGlobal practiceMELD cutoffDonor BMIOpen approachAnonymous donorsDonor surgeryArterial reconstructionDonor selectionAsia/Middle EastAnatomical variationsTransplantationLDLTPractice of living donor liver transplantationCountriesMeta-analysis and meta-regression of outcomes for adult living donor liver transplantation versus deceased donor liver transplantation
Barbetta A, Aljehani M, Kim M, Tien C, Ahearn A, Schilperoort H, Sher L, Emamaullee J. Meta-analysis and meta-regression of outcomes for adult living donor liver transplantation versus deceased donor liver transplantation. American Journal Of Transplantation 2021, 21: 2399-2412. PMID: 33300241, PMCID: PMC9048132, DOI: 10.1111/ajt.16440.Peer-Reviewed Original ResearchConceptsDeceased donor liver transplantationDonor liver transplantationHigher risk of biliary complicationsRisk of biliary complicationsLiver transplantationPatient survivalHigh riskAdult LDLTBiliary complicationsGraft survivalRates of hepatic artery thrombosisAssociated with posttransplant survivalDeceased donor liver transplant patientsLow riskAdult Living Donor Liver TransplantationLow risk of rejectionHepatic artery thrombosisSuperior patient survivalMeta-analysisAssociated with lower mortalityRisk of rejectionMeta-regression analysisPostoperative infectionWaiting timeSingle center
2020
Big Data in Transplantation Practice-the Devil Is in the Detail-Fontan-associated Liver Disease.
Kim M, Nguyen A, Lo M, Kumar S, Bucuvalas J, Glynn E, Hoffman M, Fischer R, Emamaullee J. Big Data in Transplantation Practice-the Devil Is in the Detail-Fontan-associated Liver Disease. Transplantation 2020, 105: 18-22. PMID: 32639398, DOI: 10.1097/tp.0000000000003308.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overBig DataChildChild, PreschoolData CollectionData MiningDatabases, FactualFemaleFontan ProcedureHeart Defects, CongenitalHumansInfantInfant, NewbornLiver DiseasesLiver TransplantationMaleMiddle AgedRisk AssessmentRisk FactorsTreatment OutcomeYoung AdultConceptsFontan-associated liver diseasePatients post-FontanPost-FontanLiver diseaseSingle-ventricle heart diseaseHeart-liver transplantationProgressive hepatic fibrosisMultiple health systemsConsequences of chronic exposureFontan procedureFontan RegistryNoncardiac complicationsHeart-liverTime of heartFontan hemodynamicsLiver transplantationHepatocellular carcinomaFontanHepatic fibrosisIndividual patientsHeart diseasePatientsHealth systemAffected childrenTransplantationLiver Transplantation in Patients with Sickle Cell Disease in the United States
Hogen R, Kim M, Lee Y, Lo M, Kaur N, Kahn J, Chopra S, Qazi Y, Sedra A, Kim J, O'Brien L, Genyk Y, Sher L, Emamaullee J. Liver Transplantation in Patients with Sickle Cell Disease in the United States. Journal Of Surgical Research 2020, 255: 23-32. PMID: 32540577, PMCID: PMC7541438, DOI: 10.1016/j.jss.2020.05.015.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnemia, Sickle CellBlack or African AmericanChildChild, PreschoolEnd Stage Liver DiseaseFemaleGraft SurvivalHealthcare DisparitiesHumansKidney Failure, ChronicKidney TransplantationLiver TransplantationMaleMiddle AgedRenal DialysisRetrospective StudiesTreatment OutcomeUnited StatesYoung AdultConceptsSickle cell diseaseLiver transplantationChronic liver diseasePatient survivalLT recipientsPreoperative intensive care unit admissionLiver diseaseEnd-stage liver disease scoreCell diseaseIntensive care unit admissionStable allograft functionSickle cell hepatopathyScientific RegistryLiver Disease scoreReference populationAssociated with survivalRate of chronic liver diseaseScore-matched groupsPreoperative dialysisAllograft functionLT outcomesSLKT recipientsUnit admissionPosttransplant graftViral hepatitisLong-Term Financial, Psychosocial, and Overall Health-Related Quality of Life After Living Liver Donation
Raza M, Kim M, Ding L, Fong T, Romero C, Genyk Y, Sher L, Emamaullee J. Long-Term Financial, Psychosocial, and Overall Health-Related Quality of Life After Living Liver Donation. Journal Of Surgical Research 2020, 253: 41-52. PMID: 32320896, PMCID: PMC8351216, DOI: 10.1016/j.jss.2020.03.025.Peer-Reviewed Original ResearchConceptsHealth-related quality of lifeHealth-related qualityQuality of lifeHRQOL outcomesU.S. population normsShort Form-36Quality of Life SurveyFollow-upDiverse patient populationsPhysical activityHealthy potential donorsPopulation normsLiving liver donorsShort formHealth insuranceLifetime follow-upU.S. populationQuality of Life Survey dataLife SurveyAging populationLiver donationPatient populationPostdonation follow-upOutcomesWork performance
2019
Immunologic benefit of maternal donors in pediatric living donor liver transplantation
Kim M, Akbari O, Genyk Y, Kohli R, Emamaullee J. Immunologic benefit of maternal donors in pediatric living donor liver transplantation. Pediatric Transplantation 2019, 23: e13560. PMID: 31402535, DOI: 10.1111/petr.13560.Peer-Reviewed Original ResearchConceptsLDLT recipientsPediatric LDLT recipientsPediatric LDLTImmune tolerancePost-transplantPrimary diagnosis of biliary atresiaImpact of graft typeMechanisms of immune toleranceDiagnosis of biliary atresiaOperational toleranceImprove outcomesLong-term follow-upPediatric LDLT patientsWithdrawal of immunosuppressionRegulatory T cellsImproving allograft survivalTime post-transplantDonor liver transplantationDeceased donor recipientsMaternal-fetal microchimerismRate of rejectionLDLT patientsAllograft survivalBiliary atresiaPatient survival
2011
Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice
Kim M, Kay D, Rudra R, Chen B, Hsu N, Izumiya Y, Martinez L, Spencer M, Walsh K, Grinnell A, Crosbie R. Myogenic Akt signaling attenuates muscular degeneration, promotes myofiber regeneration and improves muscle function in dystrophin-deficient mdx mice. Human Molecular Genetics 2011, 20: 1324-1338. PMID: 21245083, PMCID: PMC3049356, DOI: 10.1093/hmg/ddr015.Peer-Reviewed Original ResearchConceptsMdx miceMyofiber regenerationMuscular dystrophyTreatment of mdx miceDystrophin-deficient mdx miceMuscle functionEndogenous compensatory mechanismsExtensor digitorum longus muscleChildhood muscular dystrophyWild-type musclesDuchenne muscular dystrophyResponse relative to controlsGrip strength testImprove muscle functionAkt Signaling PathwayDystrophin-glycoprotein complexDystrophin deficiencyOverexpression of AktExtrasynaptic sarcolemmaMuscle wastingHistopathological measurementsDystrophin geneMdxRelative to controlsMuscle degeneration
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Yale School of Medicine
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New Haven, CT 06510
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