2017
Response to “Comment to the article ‘Diverse contribution of bone marrow-derived late-outgrowth endothelial progenitor cells to vascular repair under pulmonary arterial hypertension and arterial neointimal formation’”
Ikutomi M, Minami Y, Sahara M. Response to “Comment to the article ‘Diverse contribution of bone marrow-derived late-outgrowth endothelial progenitor cells to vascular repair under pulmonary arterial hypertension and arterial neointimal formation’”. Journal Of Molecular And Cellular Cardiology 2017, 103: 137-138. PMID: 28109765, DOI: 10.1016/j.yjmcc.2017.01.010.Commentaries, Editorials and LettersMeSH KeywordsArteriesBone MarrowBone Marrow CellsEndothelial Progenitor CellsHumansHypertension, PulmonaryNeointima
2015
Response to the letter by Guo et al., “Endothelial progenitor cells therapy: From bench to bedside”
Minami Y, Ikutomi M, Sahara M. Response to the letter by Guo et al., “Endothelial progenitor cells therapy: From bench to bedside”. International Journal Of Cardiology 2015, 205: 97-98. PMID: 26730839, DOI: 10.1016/j.ijcard.2015.12.026.Commentaries, Editorials and LettersDiverse contribution of bone marrow-derived late-outgrowth endothelial progenitor cells to vascular repair under pulmonary arterial hypertension and arterial neointimal formation
Ikutomi M, Sahara M, Nakajima T, Minami Y, Morita T, Hirata Y, Komuro I, Nakamura F, Sata M. Diverse contribution of bone marrow-derived late-outgrowth endothelial progenitor cells to vascular repair under pulmonary arterial hypertension and arterial neointimal formation. Journal Of Molecular And Cellular Cardiology 2015, 86: 121-135. PMID: 26231083, DOI: 10.1016/j.yjmcc.2015.07.019.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionEndothelial progenitor cellsLate outgrowth endothelial progenitor cellsEarly endothelial progenitor cellsFemoral arteryVascular repairEPC subpopulationsArterial hypertensionArterial neointimal formationProgenitor cellsBM mononuclear cellsNeointimal lesion formationFisher 344 ratsEPC treatmentEnhanced proliferation potentialPulmonary arteriolesPulmonary arteryPulmonary vasculatureEndovascular injuryMononuclear cellsVascular diseaseSystemic arteriesTherapeutic effectNeointimal formationInflammatory genesAngiogenic potential of early and late outgrowth endothelial progenitor cells is dependent on the time of emergence
Minami Y, Nakajima T, Ikutomi M, Morita T, Komuro I, Sata M, Sahara M. Angiogenic potential of early and late outgrowth endothelial progenitor cells is dependent on the time of emergence. International Journal Of Cardiology 2015, 186: 305-314. PMID: 25838182, DOI: 10.1016/j.ijcard.2015.03.166.Peer-Reviewed Original ResearchConceptsLate outgrowth endothelial progenitor cellsHuman peripheral blood mononuclear cellsLate-outgrowth EPCsEndothelial progenitor cellsEPC subpopulationsHigh angiogenic potentialAngiogenic potentialEarly outgrowth endothelial progenitor cellsDay 17Day 10Unilateral hindlimb ischemia surgeryPeripheral blood mononuclear cellsOutgrowth endothelial progenitor cellsTherapeutic angiogenic potentialProgenitor cellsBlood flow recoveryBlood mononuclear cellsTube formation capabilityVivo therapeutic efficacyIschemic legCollateral formationMononuclear cellsIschemia surgeryParacrine effectsDay 3