2022
Progress in Bioengineering Strategies for Heart Regenerative Medicine
Häneke T, Sahara M. Progress in Bioengineering Strategies for Heart Regenerative Medicine. International Journal Of Molecular Sciences 2022, 23: 3482. PMID: 35408844, PMCID: PMC8998628, DOI: 10.3390/ijms23073482.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHuman pluripotent stem cellsCardiac tissue engineering strategiesRegenerative medicineStem cell engineeringHeart regenerationNovel functional biomaterialsCardiac tissue engineeringStem cell biologyTissue engineering strategiesHeart diseasePluripotent stem cellsEngineering strategiesCell engineeringFunctional biomaterialsTissue engineeringCardiac biologyCell biologyBioengineering strategiesGreat promiseCardiomyocyte maturationDisease modelingHeart regenerative medicineInsufficient therapeutic optionsStem cellsTherapeutic applications
2019
Cardiac progenitors and paracrine mediators in cardiogenesis and heart regeneration
Witman N, Zhou C, Grote Beverborg N, Sahara M, Chien K. Cardiac progenitors and paracrine mediators in cardiogenesis and heart regeneration. Seminars In Cell And Developmental Biology 2019, 100: 29-51. PMID: 31862220, DOI: 10.1016/j.semcdb.2019.10.011.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiac progenitorsHeart regenerationCardiac progenitor cell biologyMammalian cardiac developmentProgenitor cell biologyParacrine mediatorsMorphogenetic processesCell biologyCardiac developmentMolecular mechanismsCell-free therapyCardiogenesisModern biotechnologyDiseased settingsMammalian heartProgenitorsCongenital heart diseaseRegenerative capabilityTissue engineering platformsRecent knowledgeEngineering platformHeart diseaseNovel toolHeart repairRegeneration
2018
Cardiac Progenitor Cells in Basic Biology and Regenerative Medicine
Witman N, Sahara M. Cardiac Progenitor Cells in Basic Biology and Regenerative Medicine. Stem Cells International 2018, 2018: 8283648. PMID: 29535783, PMCID: PMC5832196, DOI: 10.1155/2018/8283648.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsStem cell therapyMyocardial infarctionCardiac progenitor cellsCell therapyMajor cardiovascular eventsProgenitor cellsPreclinical animal modelsCardiovascular stem cell therapyStem cell-based approachesCardiovascular eventsStem/progenitor cell biologyDevice therapyVentricular functionMorbidity rateClinical trialsHeart diseaseProgenitor cell biologyMortality ratePharmacological agentsAnimal modelsPatient careCell-based approachesPhase ITherapyCardiac tissue
2004
[Development of blood examination method of serum amyloid A and LDL complex, and clinical application to prediction of cardiovascular event].
Mashiba S, Ogasawara K, Takeya M, Wada Y, Sahara M, Kojima S, Tabata K, Ueda M, Uchida K, Aizawa T, Kodama T. [Development of blood examination method of serum amyloid A and LDL complex, and clinical application to prediction of cardiovascular event]. Journal Of Japanese Society Of Laboratory Medicine 2004, 52: 67-74. PMID: 14968563.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseCoronary heart diseasePrediction of prognosisArtery diseaseMyocardial infarctionHeart diseaseLDL complexStable coronary artery diseaseStable coronary heart diseaseCoronary revascularization therapyProtein C reactiveDiagnostic coronary angiographyFatal myocardial infarctionHigh-sensitivity CRPCoronary artery stenosisAcute myocardial infarctionAcute phase proteinsNew markersHigh sensitivity CRP assaysC-reactiveHs-CRPIntravascular inflammationAngina pectorisCerebral infarctionBlood examination
2002
J Wave and ST Segment Elevation in the Inferior Leads
Sahara M, Sagara K, Yamashita T, Abe T, Kirigaya H, Nakada M, Iinuma H, Fu L, Watanabe H. J Wave and ST Segment Elevation in the Inferior Leads. International Heart Journal 2002, 43: 55. PMID: 12041890, DOI: 10.1536/jhj.43.55.Peer-Reviewed Case Reports and Technical NotesConceptsST-segment elevationSegment elevationInferior leadsNon-sustained monomorphic ventricular tachycardiaJ wavesStructural heart diseaseMonomorphic ventricular tachycardiaSodium channel blockersElectrophysiologic studyECG findingsHeart diseaseVentricular tachycardiaBrugada syndromeVentricular fibrillationChannel blockersHolter recordingsCircadian variationDiagnostic signsElevationPilsicainideTachycardiaPatientsFibrillationBlockersSyndrome