2019
Cardiac progenitors and paracrine mediators in cardiogenesis and heart regeneration
Witman N, Zhou C, Grote Beverborg N, Sahara M, Chien K. Cardiac progenitors and paracrine mediators in cardiogenesis and heart regeneration. Seminars In Cell And Developmental Biology 2019, 100: 29-51. PMID: 31862220, DOI: 10.1016/j.semcdb.2019.10.011.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiac progenitorsHeart regenerationCardiac progenitor cell biologyMammalian cardiac developmentProgenitor cell biologyParacrine mediatorsMorphogenetic processesCell biologyCardiac developmentMolecular mechanismsCell-free therapyCardiogenesisModern biotechnologyDiseased settingsMammalian heartProgenitorsCongenital heart diseaseRegenerative capabilityTissue engineering platformsRecent knowledgeEngineering platformHeart diseaseNovel toolHeart repairRegeneration
2015
Programming and reprogramming a human heart cell
Sahara M, Santoro F, Chien K. Programming and reprogramming a human heart cell. The EMBO Journal 2015, 34: 710-738. PMID: 25712211, PMCID: PMC4369310, DOI: 10.15252/embj.201490563.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsStem cell biologyCardiac regenerative therapeuticsHuman heart cellsCardiac regenerative medicineHuman cardiogenesisMolecular programsCell biologyRegenerative therapeuticsCardiac regenerationHeart cellsRegenerative medicineDevelopmental cardiologyLatest discoveriesNovel therapeutic toolDiseased heartCardiac muscleCellsCardiogenesisTherapeutic strategiesClinical practiceTherapeutic toolBiologyModest outcomesCurrent controversiesDeeper understanding