Madeline L. D'Aquila, MD
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Professional Highlights
About
Research
Professional Highlights
About
Research
Professional Highlights
Honors
- 1 National Award
- 1 Yale School of Medicine Award
Titles
Hospital Resident
Resident, General Surgery
Research Interests
Publications Overview
- 13 Publications
- 209 Citations
- 5 Yale Co-Authors
Research Interests
Publications Overview
- 13 Publications
- 209 Citations
- 5 Yale Co-Authors
Research Interests
Publications Overview
- 13 Publications
- 209 Citations
- 5 Yale Co-Authors
Honors
- 1 National Award
- 1 Yale School of Medicine Award
Titles
Hospital Resident
Resident, General Surgery
Research Interests
Publications Overview
- 13 Publications
- 209 Citations
- 5 Yale Co-Authors
Research Interests
Publications Overview
- 13 Publications
- 209 Citations
- 5 Yale Co-Authors
Research Interests
Publications Overview
- 13 Publications
- 209 Citations
- 5 Yale Co-Authors
Honors
- 1 National Award
- 1 Yale School of Medicine Award
About
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Titles
Hospital Resident
Resident, General Surgery
Biography
Hometown: Nashville, TN
Undergraduate: Tufts University
Medical School: Virginia Tech Carilion School of Medicine
Last Updated on November 07, 2025.
Education & Training
- MD
- Virginia Tech Carilion School of Medicine
- BS
- Tufts University
Advanced Training & Certifications
- Graduate Certificate in Research in Translational Medicine
- Virginia Polytechnic Institute and State University
Research
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Overview
Medical Research Interests
Artificial Intelligence; Colorectal Surgery; Delirium; Health Services Research; Large Language Models; Psychosocial Intervention; Veterans
ORCID
0000-0002-7444-3045
Research at a Glance
Yale Co-Authors
Frequent collaborators of Madeline L. D'Aquila's published research.
Publications Timeline
A big-picture view of Madeline L. D'Aquila's research output by year.
Research Interests
Research topics Madeline L. D'Aquila is interested in exploring.
Kate Savoie, MD, MS, FACS
Alisa Savetamal
Anne Mongiu, MD, PhD, FACS, FASCRS
Eric B Schneider, PhD
Kurt S. Schultz, MD
13Publications
209Citations
Delirium
Publications
2025
Palliative Care in Patients Admitted with Primary Burn Injury
Miller S, Graetz E, D’Aquila M, Sharan M, Schneider E, Gibbs K, Savetamal A. Palliative Care in Patients Admitted with Primary Burn Injury. Journal Of Burn Care & Research 2025, iraf218. PMID: 41288581, DOI: 10.1093/jbcr/iraf218.Peer-Reviewed Original ResearchConceptsPalliative careOlder patientsPC consultationPC encounterBurn injuryNational Inpatient SampleClinical decision-makingPC utilizationPatient comfortNonteaching hospitalsChi-square analysisHispanic patientsTeaching hospitalInpatient SampleWhite patientsNational populationOverall satisfactionPatient characteristicsRBaux scoreCareMulti-variable regressionBurn diagnosisAssociated with significant morbidityScoresPatient characteristic differencesVideo-based pelvic floor muscle therapy for patients with pelvic floor disorders: A Protocol for a prospective single-arm pilot and feasibility study
Linhares S, D’Aquila M, Schultz K, Mongiu A. Video-based pelvic floor muscle therapy for patients with pelvic floor disorders: A Protocol for a prospective single-arm pilot and feasibility study. PLOS ONE 2025, 20: e0329883. PMID: 41134840, PMCID: PMC12551819, DOI: 10.1371/journal.pone.0329883.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsQuality of lifePelvic floor rehabilitationTherapy programPost-interventionPelvic floor disordersFloor rehabilitationPatient-reported outcome measuresPost-intervention visitsIn-Person VisitsIn-person treatmentRate of non-complianceProgram usabilityEligible participantsPelvic floor muscle therapyIn-personPrimary timepointOutcome measuresProcess measuresSingle-arm designPilot trialMidpoint evaluationOnline programMuscle therapyRehabilitationSymptom changeConcurrent syringocystadenoma papilliferum and basal cell carcinoma arising from nevus sebaceous
D’Aquila M, Savoie K. Concurrent syringocystadenoma papilliferum and basal cell carcinoma arising from nevus sebaceous. BMJ Case Reports 2025, 18: e263703. PMID: 39986674, DOI: 10.1136/bcr-2024-263703.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsBasal cell carcinomaSyringocystadenoma papilliferumCell carcinomaAppropriate treatmentPresence of basal cellsMultiple skin tumorsSun-exposed areasConcurrent presentationFemale adult patientsElective excisionConcurrent skin lesionsFleshy lesionAdult patientsSkin tumorsDifferential diagnosisFollow-upCutaneous lesionsGenetic predispositionSkin lesionsLesionsBasal cellsCarcinomaPatientsTreatmentSimultaneous occurrenceSubacute haemorrhagic acalculous cholecystitis after blunt trauma in a patient on anticoagulant therapy
D'Aquila M, Savoie K. Subacute haemorrhagic acalculous cholecystitis after blunt trauma in a patient on anticoagulant therapy. BMJ Case Reports 2025, 18: e261482. PMID: 39753275, DOI: 10.1136/bcr-2024-261482.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsAcalculous cholecystitisBlunt traumaRight upper quadrant painUpper quadrant painInterval laparoscopic cholecystectomyKnown Risk FactorsCholecystostomy tubeAbdominal painAnticoagulant therapyLaparoscopic cholecystectomyAnticoagulant useDifferential diagnosisHaemorrhagic cholecystitisRisk factorsCholecystitisPatientsCholelithiasisAnticoagulationPainTraumaBluntCholecystectomyCholecystostomyMorbidityTherapy
2023
External validation of novel Revised Intensity Battle Score and comparison of static rib fracture scoring systems
Buchholz C, D'Aquila M, Lollar D. External validation of novel Revised Intensity Battle Score and comparison of static rib fracture scoring systems. Journal Of Trauma And Acute Care Surgery 2023, 96: 466-470. PMID: 37966462, DOI: 10.1097/ta.0000000000004199.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsRib fracture scoreFracture ScoreVentilator daysRib fracturesChest Trauma ScoreLevel 1 trauma centerIntensive care unit admissionInjury Severity ScoreTriage scoreScoring systemAggressive respiratory careExternal validationTriage toolReceiver operating characteristic curveArea under the receiver operating characteristic curveInclusion criteriaOperating characteristics curveUnit admissionTrauma ScoreLevel IVRespiratory careNeuraxial anesthesiaUnplanned intubationAdult patientsPoor outcome
2022
Granulomatosis With Polyangiitis Presenting as Occlusive Retinal Vasculitis
D’Aquila M, John V. Granulomatosis With Polyangiitis Presenting as Occlusive Retinal Vasculitis. Journal Of VitreoRetinal Diseases 2022, 6: 467-469. PMID: 37009531, PMCID: PMC9954774, DOI: 10.1177/24741264221076358.Peer-Reviewed Original ResearchCitationsAltmetricConceptsOcclusive retinal vasculitisRetinal vasculitisAnterior uveitisLeft eyeAntivascular endothelial growth factor injectionsPhysician awarenessOptical coherence tomography scansHistory of autoimmune diseaseCystoid macular edemaDiagnosis of GPAGrowth factor injectionsAntineutrophil cytoplasmic antibodiesCase of granulomatosisGPA managementUveitis workupFundus examinationMacular edemaRetina clinicTopical steroidsPatient's visionBlurry visionCytoplasmic antibodiesRenal biopsyTomography scanCase report
2020
Detecting Delirium: A Systematic Review of Identification Instruments for Non‐ICU Settings
Helfand B, D'Aquila M, Tabloski P, Erickson K, Yue J, Fong T, Hshieh T, Metzger E, Schmitt E, Boudreaux E, Inouye S, Jones R. Detecting Delirium: A Systematic Review of Identification Instruments for Non‐ICU Settings. Journal Of The American Geriatrics Society 2020, 69: 547-555. PMID: 33135780, PMCID: PMC7902461, DOI: 10.1111/jgs.16879.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsCOnsensus-based Standards for the selection of health Measurement INstrumentsCOnsensus-based Standards for the selectionMethodological quality reviewSystematic reviewPsychometric propertiesSelection of health Measurement INstrumentsDelirium Observation Screening ScaleHealth Measurement INstrumentsMemorial Delirium Assessment ScaleDelirium Rating Scale-Revised-98Review of psychometric propertiesIdentification instrumentEligibility of articlesDelirium Assessment ScaleConfusion Assessment MethodExcerpta Medica DatabaseWell-validated instrumentDiagnostic and Statistical ManualNarrative literature reviewManifestations of deliriumDelirium identificationNon-ICU settingsCumulative IndexWeb of ScienceScreening ScaleMachine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients
Racine A, Tommet D, D’Aquila M, Fong T, Gou Y, Tabloski P, Metzger E, Hshieh T, Schmitt E, Vasunilashorn S, Kunze L, Vlassakov K, Abdeen A, Lange J, Earp B, Dickerson B, Marcantonio E, Steingrimsson J, Travison T, Inouye S, Jones R. Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients. Journal Of General Internal Medicine 2020, 36: 265-273. PMID: 33078300, PMCID: PMC7878663, DOI: 10.1007/s11606-020-06238-7.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPost-operative deliriumObservational clinical cohort studyLogistic regressionMedical record dataConfusion Assessment MethodMental statusMedical chart reviewStepwise logistic regression modelOlder surgical patientsLogistic regression modelsProspective clinical cohortObservational cohort studyCross-validated logistic regressionOlder adultsConsensus processExpert panelCohort studyRecord dataDeliriumNon-cardiac surgeryFeature setsChart reviewRegression modelsPotential predictorsReceiver operating characteristic curveCaruncular Dacryops After Cataract Surgery With Histopathological Characterization.
Vaidya P, D'Aquila M, Ramey N, Grider D. Caruncular Dacryops After Cataract Surgery With Histopathological Characterization. American Journal Of Dermatopathology 2020, 43: e27-e29. PMID: 32956094, DOI: 10.1097/dad.0000000000001804.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsConceptsLacrimal glandCataract surgeryHistological presentationMinor lacrimal glandsLeft lacrimal glandPresence of goblet cellsPeriodic acid-Schiff-diastaseAssociated with traumaLeft eyeComplete excisionSymptoms of irritabilityLacrimal tissueLateral fornixMucicarmine stainDacryopsPhysical examHistological examinationEpithelial cellsCataractCuboidal epitheliumHistopathological characterizationSurgeryPalpebral lobeCystsFibrous tissue
2019
The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile
Hshieh T, Vasunilashorn S, D'Aquila M, Arnold S, Dickerson B, Fong T, Jones R, Marcantonio E, Schmitt E, Xu G, Gou Y, Chen F, Kunze L, Vlassakov K, Abdeen A, Lange J, Earp B, Touroutoglou A, Carlyle B, Kivisakk‐Webb P, Travison T, Dillon S, Libermann T, Inouye S, Group R, Inouye S, Arnold S, Dickerson B, Fong T, Jones R, Libermann T, Marcantonio E, Travison T, Carlyle B, Cavallari M, Dillon S, Hooker J, Hshieh T, Kandigian S, Kivisakk‐Webb P, Ngo L, Otu H, Schmitt E, Touroutoglou A, Trombetta B, Vasunilashorn S, Abdeen A, Ayres D, Earp B, Lange J, Brick G, Chen A, Davis R, Drew J, Iorio R, Kornack F, Weaver M, Webber A, Wilk R, Kunze L, Shaff D, Vlassakov K, Armstrong B, Banda A, Bertrand S, D'Aquila M, Gallagher J, Hightower B, Malloy S, Nee J, Nobuhara C, Overstreet A, Racine A, Urick D, Xu G, Arabasz G, Brickhouse M, Butterfield R, Hsu S, Makaretz S, Sore J, Chen F, Gou Y, Tommet D, Carretie S, Gruen T, Tasker K. The Role of Inflammation after Surgery for Elders (RISE) study: Study design, procedures, and cohort profile. Alzheimer's & Dementia Diagnosis Assessment & Disease Monitoring 2019, 11: 752-762. PMID: 31737775, PMCID: PMC6849121, DOI: 10.1016/j.dadm.2019.09.004.Peer-Reviewed Original ResearchCitationsAltmetricConceptsCerebrospinal fluidClinical characterizationInflammatory biomarker assaysPositron emission tomography imagingSixty-five adultsKnee arthroplastyPositron emission tomographyProspective cohort designConcurrent bloodSpinal anesthesiaInflammatory markersInflammatory biomarkersDay 1Plasma assaySurgeryTomography imagesTotal knee arthroplastyBiomarker assaysCerebrospinal fluid assaysFluid assaysFunctional statusCohort designCohort profilePatientsInflammation
Academic Achievements & Community Involvement
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Honors
honor Ira S. Goldenberg Award for Outstanding Performance as an Intern in General Surgery
06/14/2024Yale School of Medicine AwardYale General SurgeryDetailsUnited Stateshonor Alpha Omega Alpha
05/01/2023National AwardHonor Medical Society