2008
Diffusible retinal secretions regulate the expression of tight junctions and other diverse functions of the retinal pigment epithelium.
Sun R, Peng S, Chen X, Zhang H, Rizzolo LJ. Diffusible retinal secretions regulate the expression of tight junctions and other diverse functions of the retinal pigment epithelium. Molecular Vision 2008, 14: 2237-62. PMID: 19057659, PMCID: PMC2593753.Peer-Reviewed Original ResearchMeSH KeywordsActinsAdherens JunctionsAnimalsCell MembraneCells, CulturedChick EmbryoCluster AnalysisCulture Media, ConditionedDiffusionElectric ImpedanceExtracellular MatrixGene Expression ProfilingGene Expression Regulation, DevelopmentalGenomeIon ChannelsKineticsMelaninsMembrane ProteinsMicrotubulesOligonucleotide Array Sequence AnalysisPhagocytosisRetinal Pigment EpitheliumRNA, MessengerSubcellular FractionsTight JunctionsVisual PathwaysConceptsGene expression
1986
Secretion of endogenous and exogenous proteins from polarized MDCK cell monolayers.
Gottlieb T, Beaudry G, Rizzolo L, Colman A, Rindler M, Adesnik M, Sabatini D. Secretion of endogenous and exogenous proteins from polarized MDCK cell monolayers. Proceedings Of The National Academy Of Sciences Of The United States Of America 1986, 83: 2100-2104. PMID: 3083413, PMCID: PMC323238, DOI: 10.1073/pnas.83.7.2100.Peer-Reviewed Original ResearchConceptsMDCK cellsCellular endomembrane systemEpithelial cell polarityMembrane-associated precursorEndogenous productsMature secretory productCell polarityPolarized MDCK cell monolayersEndomembrane systemAlpha 2u-globulinCorresponding genesSecretory pathwayMDCK cell monolayersRegulated pathwaySecretory productsImmunoglobulin kappa chainConstitutive secretionExogenous proteinsProteolytic cleavageSorting mechanismBasolateral surfaceApical surfaceProteinVectorial secretionCell of origin