2009
Minimal Effects of VEGF and Anti-VEGF Drugs on the Permeability or Selectivity of RPE Tight Junctions
Peng S, Adelman RA, Rizzolo LJ. Minimal Effects of VEGF and Anti-VEGF Drugs on the Permeability or Selectivity of RPE Tight Junctions. Investigative Ophthalmology & Visual Science 2009, 51: 3216-3225. PMID: 20042644, PMCID: PMC2891474, DOI: 10.1167/iovs.09-4162.Peer-Reviewed Original ResearchAngiogenesis InhibitorsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabBlood-Retinal BarrierCapillary PermeabilityCells, CulturedClaudinsElectric ImpedanceEnzyme-Linked Immunosorbent AssayFluorescent Antibody Technique, IndirectGene ExpressionHumansImmunoblottingPolyethylene GlycolsPotassiumRanibizumabRetinal Pigment EpitheliumReverse Transcriptase Polymerase Chain ReactionRNA, MessengerSodiumTight JunctionsVascular Endothelial Growth Factor A
2000
Differential regulation of tight junction permeability during development of the retinal pigment epithelium
Ban Y, Rizzolo L. Differential regulation of tight junction permeability during development of the retinal pigment epithelium. American Journal Of Physiology - Cell Physiology 2000, 279: c744-c750. PMID: 10942725, DOI: 10.1152/ajpcell.2000.279.3.c744.Peer-Reviewed Original ResearchConceptsRetinal pigment epitheliumPigment epitheliumBlood-brain barrierEmbryonic ageTight junctionsTight junction permeabilityLow calcium mediumRPE developmentAcetylneuraminic acidMannitol permeabilityJunction permeabilityEpithelial regionsCulture modelDifferent subpopulationsParacellular diffusionEpitheliumDifferential regulationAgeOrder of permeation