1995
The distribution of Na+,K+-atpase and 5a11 antigen in apical microvilli of the retinal pigment epithelium is unrelated to α-spectrin
Rizzolo L, Zhou S. The distribution of Na+,K+-atpase and 5a11 antigen in apical microvilli of the retinal pigment epithelium is unrelated to α-spectrin. Journal Of Cell Science 1995, 108: 3623-3633. PMID: 8586673, DOI: 10.1242/jcs.108.11.3623.Peer-Reviewed Original ResearchConceptsAlpha-spectrinPlasma membranePlasma membrane proteinsDevelopment of polarityLateral plasma membraneBasal plasma membraneMembrane proteinsCortical cytoskeletonMacromolecular complexesBeta spectrinAnkyrinChick embryogenesisApical poleCytoskeletonEmbryonic day 6RPE microvilliLateral membranesReceptor proteinMost epitheliaSpectrin distributionΑ-spectrinApical membraneIon pumpsApical microvilliProtein
1990
The distribution of Na+,K+-ATPase in the retinal pigmented epithelium from chicken embryo is polarized in vivo but not in primary cell culture
Rizzolo L. The distribution of Na+,K+-ATPase in the retinal pigmented epithelium from chicken embryo is polarized in vivo but not in primary cell culture. Experimental Eye Research 1990, 51: 435-446. PMID: 2170160, DOI: 10.1016/0014-4835(90)90156-o.Peer-Reviewed Original ResearchConceptsBasolateral plasma membranePlasma membranePrimary cell culturesPlasma membrane proteinsFunctional tight junctionsCultured RPEChicken embryosMatrix-coated filtersExtracellular matrix coatingCell culturesMembrane proteinsVesicular stomatitis virusMorphological polarityApical poleCultured cellsApical membraneEngelbreth-HolmJunctional complexesSwarm tumorEmbryonic eyeStomatitis virusATPaseBasolateral membraneSerum-free mediumTight junctions
1986
Sorting and endocytosis of viral glycoproteins in transfected polarized epithelial cells.
Gottlieb T, Gonzalez A, Rizzolo L, Rindler M, Adesnik M, Sabatini D. Sorting and endocytosis of viral glycoproteins in transfected polarized epithelial cells. Journal Of Cell Biology 1986, 102: 1242-1255. PMID: 3007530, PMCID: PMC2114186, DOI: 10.1083/jcb.102.4.1242.Peer-Reviewed Original ResearchConceptsG proteinsCell surfaceVesicular stomatitis virusApical plasma membrane domainPlasma membrane domainsPlasma membrane proteinsCell surface domainsApical cell surfaceMadin-Darby canine kidney cellsG protein moleculesViral glycoproteinsLysosome-like vesiclesCanine kidney cellsProtein synthesis inhibitorMembrane domainsMembrane proteinsSurface domainsBasolateral domainEukaryotic expression plasmidTransfection experimentsExpression plasmidProteinPresence of chloroquineApical surfaceProtein molecules
1985
Biosynthesis and intracellular sorting of growth hormone-viral envelope glycoprotein hybrids.
Rizzolo L, Finidori J, Gonzalez A, Arpin M, Ivanov I, Adesnik M, Sabatini D. Biosynthesis and intracellular sorting of growth hormone-viral envelope glycoprotein hybrids. Journal Of Cell Biology 1985, 101: 1351-1362. PMID: 2995406, PMCID: PMC2113904, DOI: 10.1083/jcb.101.4.1351.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological TransportCell LineChlorocebus aethiopsDogsEndoplasmic ReticulumFibroblastsGenes, SyntheticGenetic VectorsGlycoproteinsGrowth HormoneHemagglutinins, ViralIntracellular MembranesKidneyMembrane ProteinsOrthomyxoviridaeProtein Processing, Post-TranslationalRecombinant ProteinsTransfectionVesicular stomatitis Indiana virusViral Envelope ProteinsConceptsCarboxy-terminal portionGolgi apparatusMembrane proteinsChimeric geneTranscription-translation experimentsPlasma membrane proteinsEndoplasmic reticulum membraneMembrane protein segmentsVesicular stomatitis virus envelope glycoproteinER membraneHybrid proteinIntracellular sortingCytoplasmic portionJuxtanuclear regionTransmembrane portionMembrane polypeptidesCarboxy terminusChimeric proteinHybrid polypeptideInsertion signalProtein segmentsSecretory polypeptidesCytoplasmic vesiclesReticulum membraneER cisternae