2023
Chapter 1 Stem cell-based organoid cultures as innovative approaches for ocular repair and regeneration
Nasonkin I, Rizzolo L. Chapter 1 Stem cell-based organoid cultures as innovative approaches for ocular repair and regeneration. 2023, 1-41. DOI: 10.1016/b978-0-323-99987-8.00005-9.Peer-Reviewed Original ResearchStem cellsDifferent ocular tissuesActual clinical impactClinical translationEndogenous stem cellsCell transplantationVision lossEfficacious therapyClinical impactAnimal modelsOcular tissuesHuman patientsImpaired visionOcular repairPatientsClinicBench discoveriesTissue stem cellsLimited proliferationOrganoid culturesCellsInitial excitementTransplantationTherapy
2013
Engineering a Blood-Retinal Barrier With Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium: Transcriptome and Functional Analysis
Peng S, Gan G, Qiu C, Zhong M, An H, Adelman RA, Rizzolo LJ. Engineering a Blood-Retinal Barrier With Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium: Transcriptome and Functional Analysis. Stem Cells Translational Medicine 2013, 2: 534-544. PMID: 23734062, PMCID: PMC3697821, DOI: 10.5966/sctm.2012-0134.Peer-Reviewed Original ResearchConceptsRetinal pigment epitheliumBlood-retinal barrierHuman retinal pigment epitheliumPigment epitheliumHuman fetal retinal pigment epitheliumOuter blood-retinal barrierTight junctionsFetal retinal pigment epitheliumEmbryonic stem cell-derived retinal pigment epitheliumAdult retinal pigment epitheliumQuantitative reverse transcription polymerase chain reactionMaturation of hESCReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionHuman embryonic stem cell-derived retinal pigment epitheliumStem cell-derived retinal pigment epitheliumRPE replacement therapyPanel of genesReplacement therapyAnimal modelsHuman embryonic stem cellsRetinal degenerationRPE functionSerum-free mediumHuman retina