Functional and structural alterations with 24-hour myocardial hibernation and recovery after reperfusion. A pig model of myocardial hibernation.
Chen C, Chen L, Fallon J, Ma L, Li L, Bow L, Knibbs D, McKay R, Gillam L, Waters D. Functional and structural alterations with 24-hour myocardial hibernation and recovery after reperfusion. A pig model of myocardial hibernation. Circulation 1996, 94: 507-16. PMID: 8759096, DOI: 10.1161/01.cir.94.3.507.Peer-Reviewed Original ResearchConceptsRegional coronary flowMyocardial hibernationCoronary flowRegional wall thickeningWall thickeningPig modelShort-term myocardial hibernationRegional lactate productionRate-pressure productCoronary artery stenosisCoronary flow reductionAcute myocardial ischemiaUltrastructural changesLactate productionLocal metabolic changesModerate flow reductionShort-term hibernationRegional oxygen consumptionFlow reductionMyocardium undergoesLAD stenosisArtery stenosisLAD flowMyocardial infarctionStructural alterations