2016
Surgical Critical Care for the Patient with Sepsis and Multiple Organ Dysfunction
Kaml GJ, Davis KA. Surgical Critical Care for the Patient with Sepsis and Multiple Organ Dysfunction. Anesthesiology Clinics 2016, 34: 681-696. PMID: 27816128, DOI: 10.1016/j.anclin.2016.06.005.Peer-Reviewed Original ResearchConceptsMultiple organ dysfunction syndromeImmune responseCurrent evidence-based treatment strategiesEvidence-based treatment strategiesSurgical intensive care unitOrgan dysfunction syndromeMultiple organ dysfunctionPatient's immune responseDefinition of sepsisIntensive care unitProcess of sepsisSurgical critical careSuccess of therapyEvidence-based interventionsDysfunction syndromeOrgan dysfunctionCare unitSeptic processTreatment strategiesCritical careSepsisClinical definitionDisease severityTimely recognitionPatients
1999
Granulocyte colony-stimulating factor and neutrophil-related changes in local host defense during recovery from shock and intra-abdominal sepsis
Davis K, Fabian T, Ragsdale D, Trenthem L, Croce M, Proctor K. Granulocyte colony-stimulating factor and neutrophil-related changes in local host defense during recovery from shock and intra-abdominal sepsis. Surgery 1999, 126: 305-313. PMID: 10455899, DOI: 10.1016/s0039-6060(99)70170-4.Peer-Reviewed Original ResearchConceptsGranulocyte colony-stimulating factorG-CSFColony-stimulating factorPMN cytotoxicityReperfusion injurySeptic focusPeritoneal PMNsResuscitation fluidExogenous granulocyte colony-stimulating factorIntra-abdominal septic focusLung tissue myeloperoxidaseIntra-abdominal sepsisBronchoalveolar lavage proteinLocal host defenseSaline solution vehicleBroad-spectrum antibioticsBronchoalveolar lavage PMNsLavage PMNsPeritoneal neutrophiliaTissue myeloperoxidaseSeptic complicationsAbdominal traumaPMN infiltrationTrauma patientsCecal ligation