1997
Mapping the distribution of outer hair cell voltage-dependent conductances by electrical amputation
Santos-Sacchi J, Huang GJ, Wu M. Mapping the distribution of outer hair cell voltage-dependent conductances by electrical amputation. Biophysical Journal 1997, 73: 1424-1429. PMID: 9284309, PMCID: PMC1181041, DOI: 10.1016/s0006-3495(97)78174-8.Peer-Reviewed Original ResearchConceptsLateral membranesVoltage magnitudeElectrical techniquesAcoustic frequencyKilohertz rangeOuter hair cell functionVoltage-dependent conductancesVoltage sensorPlasma membraneHair cell functionMechanical effectorsSynaptic poleVoltage-dependent currentsMembrane moleculesAuditory functionDense populationCell functionCable propertiesCochlear amplifierOHC motilitySensory receptors
1996
Effects of Salicylate and Lanthanides on Outer Hair Cell Motility and Associated Gating Charge
Kakehata S, Santos-Sacchi J. Effects of Salicylate and Lanthanides on Outer Hair Cell Motility and Associated Gating Charge. Journal Of Neuroscience 1996, 16: 4881-4889. PMID: 8756420, PMCID: PMC6579298, DOI: 10.1523/jneurosci.16-16-04881.1996.Peer-Reviewed Original ResearchConceptsOuter hair cellsEffects of salicylateConcentration-response curvesGuinea pig outer hair cellsOHC motilityAuditory frequency selectivityForm of salicylateHalf-maximal concentrationReversible tinnitusHearing lossDepolarized levelsHair cell motilityComparable groupsHair cellsOuter Hair Cell MotilityInner aspectOuter aspectSubsurface cisternaeTrypsin treatmentMotilityPressure changesHill coefficientSalicylatePresent experimentsVoltage-induced movement