2008
Hemichannel-Mediated Inositol 1,4,5-Trisphosphate (IP3) Release in the Cochlea: A Novel Mechanism of IP3 Intercellular Signaling
Gossman D, Zhao H. Hemichannel-Mediated Inositol 1,4,5-Trisphosphate (IP3) Release in the Cochlea: A Novel Mechanism of IP3 Intercellular Signaling. Cell Communication & Adhesion 2008, 15: 305-315. PMID: 18979296, PMCID: PMC5543712, DOI: 10.1080/15419060802357217.Peer-Reviewed Original ResearchConceptsIntercellular signalingLong-distance intercellular communicationImportant second messengerGap junction channelsGap junction hemichannel blockerGap junction hemichannelsCochlear sensory epitheliumCassette transportersSecond messengerIntercellular communicationDeafness mutantsJunction channelsCell surfaceExtracellular mediatorsSignalingNovel mechanismSensory epitheliumHemichannelsExtracellular pathwaysTrisphosphateInositolFluorescence polarization techniqueHemichannel blockersImportant roleExtracellular application
2006
Distinct and gradient distributions of connexin26 and connexin30 in the cochlear sensory epithelium of guinea pigs
Zhao H, Yu N. Distinct and gradient distributions of connexin26 and connexin30 in the cochlear sensory epithelium of guinea pigs. The Journal Of Comparative Neurology 2006, 499: 506-518. PMID: 16998915, PMCID: PMC2553046, DOI: 10.1002/cne.21113.Peer-Reviewed Original ResearchConceptsCochlear sensory epitheliumSensory epitheliumGuinea pigsHensen's cellsDeiters' cellsSpiral ganglion neuronsPillar cellsExpression of Cx26Auditory sensory epitheliumDistinct cellular expressionGanglion neuronsCochlear apexCx26 labelingCell bodiesCx26 expressionImmunofluorescent stainingEpitheliumHair cellsCellular expressionCx30Dense labelingClaudius cellsCell preparationsPredominant isoformCellular distribution
2001
Long-term natural culture of cochlear sensory epithelia of guinea pigs
Zhao H. Long-term natural culture of cochlear sensory epithelia of guinea pigs. Neuroscience Letters 2001, 315: 73-76. PMID: 11711218, DOI: 10.1016/s0304-3940(01)02357-6.Peer-Reviewed Original ResearchConceptsCochlear sensory epitheliumCochlear sensory epithelial cellsSensory epithelial cellsSensory epitheliumHair cell markersCochlear cell lineIsolated cell clonesCochlear cellsEpithelial morphotypeGenetic manipulationProtein ZO-1Genetic studiesValuable cell sourceCulture cellsGuinea pigsCell linesEpithelial cellsZO-1Tight junctionsCell markersNatural cultureCell sourceCellsCell clonesCulture medium