2005
Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear
Zhao H, Yu N, Fleming C. Gap junctional hemichannel-mediated ATP release and hearing controls in the inner ear. Proceedings Of The National Academy Of Sciences Of The United States Of America 2005, 102: 18724-18729. PMID: 16344488, PMCID: PMC1317927, DOI: 10.1073/pnas.0506481102.Peer-Reviewed Original ResearchConceptsHemichannel-mediated ATP releaseHair cellsGap junctional blockerActive cochlear amplifierAuditory sensory hair cellsSensory hair cellsEffect of ATPP2 receptorsExtracellular Ca2OHC electromotilityCochlear sensitivityATP releaseConnexin gap junctionsExtracellular ATPConnexin expressionInner earImmunofluorescent stainingHearing controlsHearing sensitivityOuter hair cell electromotilityCochleaHair cell electromotilityConnexin hemichannelsCochlear fluidsGap junctional channels
2001
Chlorpromazine Alters Outer Hair Cell Electromotility
Lue A, Zhao H, Brownell W. Chlorpromazine Alters Outer Hair Cell Electromotility. Otolaryngology 2001, 125: 71-76. PMID: 11458218, DOI: 10.1067/mhn.2001.116446.Peer-Reviewed Original ResearchConceptsOuter hair cellsHair cellsDose-dependent depolarizationGuinea pig outer hair cellsEffect of chlorpromazineElectromotile responseAntipsychotic medicationChlorpromazine treatmentHearing thresholdsLarge dosesCochlear sensitivityOtoacoustic emissionsInner earChlorpromazineOuter Hair Cell ElectromotilityHair cell electromotilityOHC electromotilityMembrane voltageRecording conditionsCellsMedicationsResponseElectromotility