2020
Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic CHEST Expert Panel Report
Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA. Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic CHEST Expert Panel Report. Journal Of The American College Of Radiology 2020, 17: 845-854. PMID: 32485147, PMCID: PMC7177099, DOI: 10.1016/j.jacr.2020.04.024.Peer-Reviewed Original ResearchConceptsLung cancer screeningCell lung cancerCancer screeningLung nodule evaluationConsensus statementLung nodulesLung cancerStage INodule evaluationAnnual lung cancer screeningHigh-risk lung nodulesLung cancer screening programsClinical stage ICHEST Expert Panel ReportCurrent guideline recommendationsCancer screening programsPatient-related factorsCommon clinical scenariosCoronavirus disease 2019Balance of benefitsIndividual patient careCOVID-19 pandemicExpert Panel ReportPotential exposureGuideline recommendationsApproach to the Subsolid Nodule
Mase VJ, Detterbeck FC. Approach to the Subsolid Nodule. Clinics In Chest Medicine 2020, 41: 99-113. PMID: 32008632, DOI: 10.1016/j.ccm.2019.11.004.Peer-Reviewed Original Research
2018
Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose
Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.Peer-Reviewed Original ResearchConceptsPopulation-based input functionStandardized uptake valueImage-derived input functionLung nodulesClinical trialsTime-activity curvesLow-dose computed tomography (LDCT) screeningLung cancer mortality ratesIndeterminate lung nodulesComputed Tomography ScreeningF-FDG PETCancer mortality ratesStatic PET acquisitionVirtual clinical trialsScan durationTomography screeningFDG injectionPET scansMortality rateUptake valueAccurate diagnosisMalignant lung nodulesROC analysisPatient dataMalignant nodules
2015
Components Necessary for High-Quality Lung Cancer Screening American College of Chest Physicians and American Thoracic Society Policy Statement
Mazzone P, Powell CA, Arenberg D, Bach P, Detterbeck F, Gould MK, Jaklitsch MT, Jett J, Naidich D, Vachani A, Wiener RS, Silvestri G. Components Necessary for High-Quality Lung Cancer Screening American College of Chest Physicians and American Thoracic Society Policy Statement. CHEST Journal 2015, 147: 295-303. PMID: 25356819, PMCID: PMC4502754, DOI: 10.1378/chest.14-2500.Peer-Reviewed Original ResearchMeSH KeywordsHealth PolicyHumansLung NeoplasmsMass ScreeningRisk AssessmentSolitary Pulmonary NoduleTomography, X-Ray ComputedConceptsLung cancer screening programsCancer screening programsLung cancer screeningAmerican Thoracic SocietyCancer screeningScreening programChest PhysiciansAmerican CollegeHigh-quality lung cancer screening programThoracic Oncology NetworkEvidence-based reviewLow-dose chest CT scansChest CT scanAmerican Cancer SocietyLung cancerComponents of screeningEssential program componentsThoracic SocietyOncology NetworkCancer SocietyCT scanProgram componentsPreventive oncologyAmerican SocietyScreening facility
2011
Approach to the Ground-Glass Nodule
Detterbeck FC, Homer RJ. Approach to the Ground-Glass Nodule. Clinics In Chest Medicine 2011, 32: 799-810. PMID: 22054887, DOI: 10.1016/j.ccm.2011.08.002.Peer-Reviewed Original ResearchMeSH KeywordsHumansLung NeoplasmsMultiple Pulmonary NodulesPneumonectomyPositron-Emission TomographyRisk FactorsSolitary Pulmonary NoduleTomography, X-Ray ComputedWatchful Waiting
2004
Seeking a Home for a PET, Part 1 Defining the Appropriate Place for Positron Emission Tomography Imaging in the Diagnosis of Pulmonary Nodules or Masses
Detterbeck FC, Falen S, Rivera MP, Halle JS, Socinski MA. Seeking a Home for a PET, Part 1 Defining the Appropriate Place for Positron Emission Tomography Imaging in the Diagnosis of Pulmonary Nodules or Masses. CHEST Journal 2004, 125: 2294-2299. PMID: 15189954, DOI: 10.1378/chest.125.6.2294.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDiagnosis, DifferentialFemaleHumansLung DiseasesLung NeoplasmsMaleSensitivity and SpecificitySolitary Pulmonary NoduleTomography, Emission-ComputedConceptsPositron emission tomographyLung cancerPulmonary nodulesEmission tomographyTypical carcinoid tumorEvaluation of symptomsIntermediate riskCarcinoid tumorsPulmonary lesionsBronchioloalveolar carcinomaRisk factorsHigh riskRadiographic appearancePatientsPET imagingLesionsDiagnosisLittle roleCancerTomographyRiskNodulesCarcinomaSymptomsTumors